Protein: RIR2B
Ribonucleoside-diphosphate reductase subunit M2 B (EC 1.17.4.1) (TP53-inducible ribonucleotide reductase M2 B) (p53-inducible ribonucleotide reductase small subunit 2-like protein) (p53R2)

Gene: RIR2B, RRM2B
Organism: Homo sapiens
Interactions: 52
UniProt ID: Q7LG56

Gene Ontology (top 5):
GO:0000731 - DNA synthesis involved in DNA repair
GO:0001822 - kidney development
GO:0003014 - renal system process
GO:0004748 - ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

621259

RIR1
Ribonucleoside-diphosphate reductase large subunit

4

13

Small-scale

0.897

High

679622

RIR2
Ribonucleoside-diphosphate reductase subunit M2

3

15

High-throughput

0.861

High

1185585

RIR2B
Ribonucleoside-diphosphate reductase subunit M2 B

3

15

Small-scale

0.839

High

176462

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

3

1

High-throughput

0.667

High

1185602

FZR1
Fizzy-related protein homolog

2

3

High-throughput

0.628

High

386991

P53
Cellular tumor antigen p53

2

1

Small-scale

0.611

High

1031554

ATM
Serine-protein kinase ATM

1

0

Small-scale

0.576

High

962837

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.564

High

217818

ORC4
Origin recognition complex subunit 4

1

0

High-throughput

0.557

High

1185597

RNF41
E3 ubiquitin-protein ligase NRDP1

1

0

High-throughput

0.549

High

229693

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

1

High-throughput

0.536

High

323859

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.536

High

871637

HSP72
Heat shock-related 70 kDa protein 2

1

2

High-throughput

0.536

High

758275

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

Small-scale

0.529

High

434400

TPM2
Tropomyosin beta chain

1

0

High-throughput

0.513

High

941096

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.513

High

1185593

SOSB1
SOSS complex subunit B1

1

0

High-throughput

0.513

High

1185598

ENTP7
Ectonucleoside triphosphate diphosphohydrolase 7

1

0

High-throughput

0.513

High

942751

SRPK2
SRSF protein kinase 2

1

0

High-throughput

0.480

High

246241

NBN
Nibrin

1

0

Small-scale

0.479

High

837036

MRE11
Double-strand break repair protein MRE11

1

0

Small-scale

0.479

High

1185591

RAD50
DNA repair protein RAD50

1

0

Small-scale

0.479

High

177922

TMPS2
Transmembrane protease serine 2

1

2

High-throughput

0.479

High

328880

TOP3B
DNA topoisomerase 3-beta-1

1

1

High-throughput

0.479

High

861814

PLK1
Serine/threonine-protein kinase PLK1

1

3

High-throughput

0.479

High

1146556

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.479

High

1185587

SIR6
NAD-dependent protein deacylase sirtuin-6

1

1

High-throughput

0.479

High

1185590

CLC4D
C-type lectin domain family 4 member D

1

2

High-throughput

0.479

High

456891

FURIN
Furin

1

0

High-throughput

0.458

High

726283

BASI
Basigin

1

0

High-throughput

0.458

High

832550

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

855922

ZN131
Zinc finger protein 131

1

0

High-throughput

0.458

High

1185589

ATRIP
ATR-interacting protein

1

0

Small-scale

0.458

High

1185592

BROMI
Protein broad-minded

1

0

Small-scale

0.458

High

1185594

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

1185596

AICDA
Single-stranded DNA cytosine deaminase

1

0

Small-scale

0.458

High

601537

FGFR2
Fibroblast growth factor receptor 2

1

3

High-throughput

0.457

High

441529

MET
Hepatocyte growth factor receptor

1

1

High-throughput

0.437

High

1170564

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1185586

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.437

High

1185599

TMPS4
Transmembrane protease serine 4

1

2

High-throughput

0.437

High

1185601

CLC4E
C-type lectin domain family 4 member E

1

2

High-throughput

0.437

High

1185600

TMOD2
Tropomodulin-2

3

0

High-throughput

0.347

High

894704

GMFB
Glia maturation factor beta

1

0

High-throughput

0.279

Low

1075425

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

0

High-throughput

0.279

Low

1185588

TM263
Transmembrane protein 263

1

0

High-throughput

0.279

Low

600599

EPHA1
Ephrin type-A receptor 1

1

0

High-throughput

0.261

Low

429909

CATL1
Procathepsin L

1

0

High-throughput

0.249

Low

648808

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.249

Low

965729

IFM3
Interferon-induced transmembrane protein 3

1

0

High-throughput

0.249

Low

1185595

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024