HitPredict

Interactor 1: LIRB2 (Q8N423)
Leukocyte immunoglobulin-like receptor subfamily B member 2 (LIR-2) (Leukocyte immunoglobulin-like receptor 2) (CD85 antigen-like family member D) (Immunoglobulin-like transcript 4) (ILT-4) (Monocyte/macrophage immunoglobulin-like receptor 10) (MIR-10) (CD antigen CD85d)
Gene: LILRB2

Interactor 2: Q95J06 (Q95J06)
HLA class I histocompatibility antigen A alpha chain (MHC class I antigen) (MHC class I protein) (MHC leukocyte antigen) (Major histocompatibility complex, class I, A)
Gene: HLA-A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27649529
Identification Methods	surface plasmon resonance
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1-set~ig, MHC_I~ig, C1-set~Ig_2
Common GO terms	GO:0005615 - extracellular space GO:0006955 - immune response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 597 Hs			1 365
+	Hs
		382478 LIRB2_HUMAN (1-597): 8.63e-135: 407: 100.00		HLAA_HUMAN (1-365): 2.79e-175: 493: 92.33
+	Hs
		1130837 LIRB2_HUMAN (1-597): 8.63e-135: 407: 100.00		Q5S3G3_HUMAN (1-365): 4.46e-175: 492: 92.06
+	Hs
		1245576 LIRB1_HUMAN (1-597): 1.37e-123: 380: 76.92		Q95J06_HUMAN (1-365): 3.04e-180: 505: 100.00
+	Hs
		382485 LIRB1_HUMAN (1-597): 1.37e-123: 380: 76.92		HLAA_HUMAN (1-365): 2.79e-175: 493: 92.33
+	Hs
		1130838 LIRB1_HUMAN (1-597): 1.37e-123: 380: 76.92		Q5S3G3_HUMAN (1-365): 4.46e-175: 492: 92.06
+	Hs
		354505 LIRB2_HUMAN (1-597): 8.63e-135: 407: 100.00		HLAB_HUMAN (1-362): 7.73e-155: 441: 84.81
+	Hs
		488292 LIRB2_HUMAN (1-597): 8.63e-135: 407: 100.00		HLAC_HUMAN (1-364): 5.42e-149: 426: 78.63
+	Hs
		570343 LIRB2_HUMAN (1-597): 8.63e-135: 407: 100.00		HLAG_HUMAN (1-338): 6.03e-148: 422: 81.95
+	Hs
		354513 LIRB1_HUMAN (1-597): 1.37e-123: 380: 76.92		HLAB_HUMAN (1-362): 7.73e-155: 441: 84.81
+	Hs
		673968 LIRB2_HUMAN (1-597): 8.63e-135: 407: 100.00		HLAF_HUMAN (4-348): 2.53e-139: 401: 80.87
+	Hs
		488307 LIRB1_HUMAN (1-597): 1.37e-123: 380: 76.92		HLAC_HUMAN (1-364): 5.42e-149: 426: 78.63
+	Hs
		570351 LIRB1_HUMAN (1-597): 1.37e-123: 380: 76.92		HLAG_HUMAN (1-338): 6.03e-148: 422: 81.95
+	Hs
		673969 LIRB1_HUMAN (1-597): 1.37e-123: 380: 76.92		HLAF_HUMAN (4-348): 2.53e-139: 401: 80.87
+	Hs
		382420 KI3S1_HUMAN (1-344): 4.79e-67: 224: 37.93		HLAA_HUMAN (1-365): 2.79e-175: 493: 92.33
+	Hs
		354352 KI3L1_HUMAN (1-333): 1.59e-66: 225: 38.58		HLAB_HUMAN (1-362): 7.73e-155: 441: 84.81
+	Hs
		354449 KI3S1_HUMAN (1-344): 4.79e-67: 224: 37.93		HLAB_HUMAN (1-362): 7.73e-155: 441: 84.81
+	Hs
		488221 KI3S1_HUMAN (1-344): 4.79e-67: 224: 37.93		HLAC_HUMAN (1-364): 5.42e-149: 426: 78.63
+	Hs
		570311 KI3L1_HUMAN (1-333): 1.59e-66: 225: 38.58		HLAG_HUMAN (1-338): 6.03e-148: 422: 81.95
+	Hs
		673944 KI3L1_HUMAN (1-333): 1.59e-66: 225: 38.58		HLAF_HUMAN (4-348): 2.53e-139: 401: 80.87
+	Hs
		673954 KI3S1_HUMAN (1-344): 4.79e-67: 224: 37.93		HLAF_HUMAN (4-348): 2.53e-139: 401: 80.87