Protein: ACL6A
Actin-like protein 6A (53 kDa BRG1-associated factor A) (Actin-related protein Baf53a) (ArpNbeta) (BRG1-associated factor 53A) (BAF53A) (INO80 complex subunit K)

Gene: ACL6A, ACTL6A
Organism: Homo sapiens
Interactions: 239
UniProt ID: O96019

Gene Ontology (top 5):
GO:0000723 - telomere maintenance
GO:0000776 - kinetochore
GO:0000785 - chromatin
GO:0000786 - nucleosome
GO:0001825 - blastocyst formation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

355172

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

13

20

Small-scale

0.975

High

355326

RUVB1
RuvB-like 1

7

15

Small-scale

0.962

High

355325

RUVB2
RuvB-like 2

7

15

Small-scale

0.958

High

355171

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

7

20

Small-scale

0.949

High

355303

DMAP1
DNA methyltransferase 1-associated protein 1

3

10

Small-scale

0.855

High

355186

ACTG
Actin, cytoplasmic 2

3

19

High-throughput

0.847

High

355191

TCPB
T-complex protein 1 subunit beta

4

20

High-throughput

0.808

High

355178

ACTB
Actin, cytoplasmic 1

2

19

High-throughput

0.789

High

355300

ARP5
Actin-related protein 5

2

19

High-throughput

0.789

High

355140

TCPA
T-complex protein 1 subunit alpha

3

16

High-throughput

0.770

High

355260

TCPW
T-complex protein 1 subunit zeta-2

3

20

High-throughput

0.770

High

355222

VPS72
Vacuolar protein sorting-associated protein 72 homolog

2

2

Small-scale

0.759

High

355204

FLII
Protein flightless-1 homolog

2

19

Small-scale

0.754

High

355271

FBXW7
F-box/WD repeat-containing protein 7

2

7

Small-scale

0.754

High

355280

EP400
E1A-binding protein p400

2

20

Small-scale

0.754

High

355120

MYC
Myc proto-oncogene protein

9

11

Small-scale

0.751

High

355202

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

7

7

Small-scale

0.745

High

355299

ARP8
Actin-related protein 8

2

20

High-throughput

0.737

High

355323

RHG26
Rho GTPase-activating protein 26

2

16

High-throughput

0.737

High

355266

REQU
Zinc finger protein ubi-d4

6

20

Small-scale

0.733

High

355278

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

6

16

High-throughput

0.732

High

355270

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

6

7

Small-scale

0.730

High

355265

DPF3
Zinc finger protein DPF3

6

20

Small-scale

0.729

High

355145

TYY1
Transcriptional repressor protein YY1

5

8

Small-scale

0.727

High

355255

SMRC2
SWI/SNF complex subunit SMARCC2

5

18

High-throughput

0.718

High

355128

H2AZ
Histone H2A.Z

5

9

Small-scale

0.712

High

355153

TCPZ
T-complex protein 1 subunit zeta

2

18

High-throughput

0.705

High

355164

TCPG
T-complex protein 1 subunit gamma

2

20

High-throughput

0.705

High

355259

BCL7C
B-cell CLL/lymphoma 7 protein family member C

4

11

Small-scale

0.699

High

355219

SSXT
Protein SSXT

4

20

High-throughput

0.694

High

355175

NEK4
Serine/threonine-protein kinase Nek4

1

14

High-throughput

0.691

High

355226

BCL7A
B-cell CLL/lymphoma 7 protein family member A

4

11

High-throughput

0.691

High

355267

SMRC1
SWI/SNF complex subunit SMARCC1

4

18

Small-scale

0.691

High

355269

KAT5
Histone acetyltransferase KAT5

4

13

Small-scale

0.690

High

355328

TRRAP
Transformation/transcription domain-associated protein

4

2

Small-scale

0.686

High

211617

ZNHI1
Zinc finger HIT domain-containing protein 1

4

2

Small-scale

0.683

High

355308

MRGBP
MRG/MORF4L-binding protein

4

4

Small-scale

0.683

High

154597

ARI1A
AT-rich interactive domain-containing protein 1A

3

17

High-throughput

0.667

High

355272

H2B1A
Histone H2B type 1-A

3

9

High-throughput

0.667

High

355305

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

3

4

High-throughput

0.667

High

355314

MO4L1
Mortality factor 4-like protein 1

3

8

Small-scale

0.650

High

355250

IN80E
INO80 complex subunit E

4

0

Small-scale

0.649

High

355143

CDK2
Cyclin-dependent kinase 2

1

6

Small-scale

0.647

High

355169

CDK9
Cyclin-dependent kinase 9

1

14

Small-scale

0.647

High

355131

ANDR
Androgen receptor

3

11

Small-scale

0.640

High

355160

YAP1
Transcriptional coactivator YAP1

3

15

Small-scale

0.640

High

355152

FEN1
Flap endonuclease 1

2

1

High-throughput

0.628

High

355258

PHF10
PHD finger protein 10

2

20

High-throughput

0.628

High

355161

CAPZB
F-actin-capping protein subunit beta

1

4

High-throughput

0.618

High

355118

ACL6A
Actin-like protein 6A

1

18

High-throughput

0.618

High

355150

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

9

High-throughput

0.618

High

355170

TCPD
T-complex protein 1 subunit delta

1

18

High-throughput

0.618

High

355205

PHLP
Phosducin-like protein

1

10

High-throughput

0.618

High

355234

IN80C
INO80 complex subunit C

1

1

High-throughput

0.618

High

355295

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

20

High-throughput

0.618

High

355298

WDR76
WD repeat-containing protein 76

1

9

High-throughput

0.618

High

355321

INO80
Chromatin-remodeling ATPase INO80

1

20

Small-scale

0.618

High

329685

ZRAB2
Zinc finger Ran-binding domain-containing protein 2

2

1

High-throughput

0.611

High

355167

HINT1
Adenosine 5'-monophosphoramidase HINT1

2

1

High-throughput

0.611

High

355199

MBTD1
MBT domain-containing protein 1

2

2

Small-scale

0.611

High

355210

CUL3
Cullin-3

2

10

High-throughput

0.611

High

355240

HDGR2
Hepatoma-derived growth factor-related protein 2

2

6

High-throughput

0.611

High

355253

ARI1B
AT-rich interactive domain-containing protein 1B

2

16

High-throughput

0.611

High

355264

DPF1
Zinc finger protein neuro-d4

2

20

High-throughput

0.611

High

355268

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

2

16

High-throughput

0.611

High

355311

ING3
Inhibitor of growth protein 3

2

5

Small-scale

0.601

High

355189

ACTC
Actin, alpha cardiac muscle 1

1

19

High-throughput

0.595

High

355130

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

4

High-throughput

0.595

High

355144

BRD2
Bromodomain-containing protein 2

2

20

High-throughput

0.584

High

355184

H2B1C
Histone H2B type 1-C/E/F/G/I

2

9

High-throughput

0.584

High

355190

H31
Histone H3.1

2

5

High-throughput

0.584

High

355215

MO4L2
Mortality factor 4-like protein 2

2

8

Small-scale

0.584

High

355243

PB1
Protein polybromo-1

2

20

Small-scale

0.584

High

355297

BRD9
Bromodomain-containing protein 9

2

18

High-throughput

0.584

High

355304

BRD7
Bromodomain-containing protein 7

2

17

High-throughput

0.584

High

355312

BICRA
BRD4-interacting chromatin-remodeling complex-associated protein

2

14

Small-scale

0.584

High

355121

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

4

High-throughput

0.575

High

355229

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

10

High-throughput

0.575

High

355148

BMI1
Polycomb complex protein BMI-1

2

17

High-throughput

0.571

High

355236

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

2

16

Small-scale

0.571

High

355289

IN80B
INO80 complex subunit B

2

1

High-throughput

0.571

High

355119

NB5R3
NADH-cytochrome b5 reductase 3

2

1

High-throughput

0.558

High

156816

CTRO
Citron Rho-interacting kinase

1

10

High-throughput

0.553

High

355155

M3K8
Mitogen-activated protein kinase kinase kinase 8

1

6

High-throughput

0.553

High

355187

ACTH
Actin, gamma-enteric smooth muscle

1

19

High-throughput

0.553

High

355230

A16L1
Autophagy-related protein 16-1

1

8

High-throughput

0.553

High

355284

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.553

High

355227

IN80D
INO80 complex subunit D

2

0

High-throughput

0.547

High

355275

MCRS1
Microspherule protein 1

2

0

High-throughput

0.547

High

355198

EWS
RNA-binding protein EWS

1

5

High-throughput

0.541

High

186829

FOXN1
Forkhead box protein N1

1

2

High-throughput

0.536

High

340276

YETS4
YEATS domain-containing protein 4

1

6

High-throughput

0.536

High

355127

PARP1
Poly [ADP-ribose] polymerase 1

1

2

High-throughput

0.536

High

355133

TOP1
DNA topoisomerase 1

1

2

High-throughput

0.536

High

355136

ITF2
Transcription factor 4

1

2

High-throughput

0.536

High

355151

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

2

High-throughput

0.536

High

355158

CBX5
Chromobox protein homolog 5

1

2

Small-scale

0.536

High

355192

CBX1
Chromobox protein homolog 1

1

2

High-throughput

0.536

High

355200

SSRP1
FACT complex subunit SSRP1

1

4

High-throughput

0.536

High

355211

SCRB2
Lysosome membrane protein 2

1

2

High-throughput

0.536

High

355214

NUMA1
Nuclear mitotic apparatus protein 1

1

20

High-throughput

0.536

High

355224

H2B2E
Histone H2B type 2-E

1

9

High-throughput

0.536

High

355235

FOXR1
Forkhead box protein R1

1

1

High-throughput

0.536

High

355246

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

3

High-throughput

0.536

High

355248

H2B3B
Histone H2B type 3-B

1

9

High-throughput

0.536

High

355263

HDAC2
Histone deacetylase 2

1

7

High-throughput

0.536

High

355294

EPC1
Enhancer of polycomb homolog 1

1

3

Small-scale

0.536

High

355329

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

13

Small-scale

0.536

High

355154

CCNF
Cyclin-F

1

2

High-throughput

0.515

High

355196

RELB
Transcription factor RelB

1

9

High-throughput

0.515

High

328618

VAMP5
Vesicle-associated membrane protein 5

1

0

High-throughput

0.513

High

355138

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.513

High

185328

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

6

High-throughput

0.501

High

355225

KIF7
Kinesin-like protein KIF7

1

2

High-throughput

0.489

High

355317

S18L2
SS18-like protein 2

1

10

High-throughput

0.489

High

355176

GDIR1
Rho GDP-dissociation inhibitor 1

1

1

High-throughput

0.481

High

355177

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

High-throughput

0.480

High

131648

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

6

High-throughput

0.479

High

142782

NFIB
Nuclear factor 1 B-type

1

3

High-throughput

0.479

High

240416

PRKN
E3 ubiquitin-protein ligase parkin

1

13

High-throughput

0.479

High

259272

BRD4
Bromodomain-containing protein 4

1

13

High-throughput

0.479

High

273964

CREST
Calcium-responsive transactivator

1

20

High-throughput

0.479

High

302293

RNF8
E3 ubiquitin-protein ligase RNF8

1

11

High-throughput

0.479

High

314992

RECQ4
ATP-dependent DNA helicase Q4

1

10

High-throughput

0.479

High

325638

UBR5
E3 ubiquitin-protein ligase UBR5

1

10

Small-scale

0.479

High

334485

ZBT7A
Zinc finger and BTB domain-containing protein 7A

1

7

Small-scale

0.479

High

334957

ARI2
E3 ubiquitin-protein ligase ARIH2

1

14

High-throughput

0.479

High

340799

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

10

High-throughput

0.479

High

355122

MYCN
N-myc proto-oncogene protein

1

11

High-throughput

0.479

High

355123

NTRK1
High affinity nerve growth factor receptor

1

9

High-throughput

0.479

High

355124

P53
Cellular tumor antigen p53

1

4

Small-scale

0.479

High

355126

NFIC
Nuclear factor 1 C-type

1

7

High-throughput

0.479

High

355129

TFPT
TCF3 fusion partner

1

1

High-throughput

0.479

High

355132

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.479

High

355134

MYCL
Protein L-Myc

1

11

Small-scale

0.479

High

355137

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

355139

CEBPB
CCAAT/enhancer-binding protein beta

1

5

High-throughput

0.479

High

355141

NUCL
Nucleolin

1

4

High-throughput

0.479

High

355142

GATA2
Endothelial transcription factor GATA-2

1

1

High-throughput

0.479

High

355146

H2B1B
Histone H2B type 1-B

1

9

High-throughput

0.479

High

355147

CTNB1
Catenin beta-1

1

7

High-throughput

0.479

High

355156

GATA4
Transcription factor GATA-4

1

1

High-throughput

0.479

High

355159

RECQ1
ATP-dependent DNA helicase Q1

1

7

High-throughput

0.479

High

355162

SOX2
Transcription factor SOX-2

1

4

High-throughput

0.479

High

355163

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

4

High-throughput

0.479

High

355166

CEBPA
CCAAT/enhancer-binding protein alpha

1

4

High-throughput

0.479

High

355168

MAP2
Methionine aminopeptidase 2

1

3

High-throughput

0.479

High

355173

MECP2
Methyl-CpG-binding protein 2

1

3

High-throughput

0.479

High

355174

HDGF
Hepatoma-derived growth factor

1

3

High-throughput

0.479

High

355179

RAB14
Ras-related protein Rab-14

1

3

High-throughput

0.479

High

355180

MAX
Protein max

1

11

Small-scale

0.479

High

355181

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

355183

H4
Histone H4

1

3

High-throughput

0.479

High

355185

GRB2
Growth factor receptor-bound protein 2

1

13

High-throughput

0.479

High

355188

CSK2B
Casein kinase II subunit beta

1

2

High-throughput

0.479

High

355193

H33
Histone H3.3

1

5

High-throughput

0.479

High

355194

VIGLN
Vigilin

1

11

High-throughput

0.479

High

355195

RUNX1
Runt-related transcription factor 1

1

1

High-throughput

0.479

High

355197

FLI1
Friend leukemia integration 1 transcription factor

1

4

Small-scale

0.479

High

355201

EP300
Histone acetyltransferase p300

1

17

High-throughput

0.479

High

355203

NFIA
Nuclear factor 1 A-type

1

4

High-throughput

0.479

High

355206

IKZF1
DNA-binding protein Ikaros

1

5

High-throughput

0.479

High

355207

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

9

High-throughput

0.479

High

355208

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

355213

NFIX
Nuclear factor 1 X-type

1

4

High-throughput

0.479

High

355216

KIF14
Kinesin-like protein KIF14

1

5

High-throughput

0.479

High

355217

BRD3
Bromodomain-containing protein 3

1

12

High-throughput

0.479

High

355218

SF3A1
Splicing factor 3A subunit 1

1

4

High-throughput

0.479

High

355220

SF01
Splicing factor 1

1

4

High-throughput

0.479

High

355221

SMAD1
Mothers against decapentaplegic homolog 1

1

2

Small-scale

0.479

High

355223

HIF1A
Hypoxia-inducible factor 1-alpha

1

3

High-throughput

0.479

High

355228

BRDT
Bromodomain testis-specific protein

1

14

High-throughput

0.479

High

355231

ARID2
AT-rich interactive domain-containing protein 2

1

16

High-throughput

0.479

High

355232

BICRL
BRD4-interacting chromatin-remodeling complex-associated protein-like

1

2

Small-scale

0.479

High

355233

NFRKB
Nuclear factor related to kappa-B-binding protein

1

8

High-throughput

0.479

High

355238

MOB3C
MOB kinase activator 3C

1

2

High-throughput

0.479

High

355239

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

355241

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

6

High-throughput

0.479

High

355242

SLN11
Schlafen family member 11

1

1

Small-scale

0.479

High

355245

ZCH18
Zinc finger CCCH domain-containing protein 18

1

11

High-throughput

0.479

High

355247

SLX4
Structure-specific endonuclease subunit SLX4

1

13

High-throughput

0.479

High

355249

SIR6
NAD-dependent protein deacylase sirtuin-6

1

1

High-throughput

0.479

High

355254

SNIP1
Smad nuclear-interacting protein 1

1

2

Small-scale

0.479

High

355256

TIP
T-cell immunomodulatory protein

1

2

High-throughput

0.479

High

355261

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

13

High-throughput

0.479

High

355262

ESR2
Estrogen receptor beta

1

11

High-throughput

0.479

High

355273

CHM4C
Charged multivesicular body protein 4c

1

5

High-throughput

0.479

High

355276

TRI11
E3 ubiquitin-protein ligase TRIM11

1

9

Small-scale

0.479

High

355277

CDCA5
Sororin

1

1

High-throughput

0.479

High

355279

DDRGK
DDRGK domain-containing protein 1

1

2

High-throughput

0.479

High

355281

CI072
Guanine nucleotide exchange factor C9orf72

1

6

High-throughput

0.479

High

355282

CIC
Protein capicua homolog

1

8

High-throughput

0.479

High

355285

ANM1
Protein arginine N-methyltransferase 1

1

4

High-throughput

0.479

High

355286

BCL7B
B-cell CLL/lymphoma 7 protein family member B

1

11

High-throughput

0.479

High

355288

FACD2
Fanconi anemia group D2 protein

1

7

High-throughput

0.479

High

355290

WWTR1
WW domain-containing transcription regulator protein 1

1

11

High-throughput

0.479

High

355291

BRD8
Bromodomain-containing protein 8

1

20

High-throughput

0.479

High

355293

ING2
Inhibitor of growth protein 2

1

10

Small-scale

0.479

High

355296

PKHA4
Pleckstrin homology domain-containing family A member 4

1

18

High-throughput

0.479

High

355306

ANLN
Anillin

1

9

High-throughput

0.479

High

355307

FBX6
F-box only protein 6

1

1

High-throughput

0.479

High

355313

HECW2
E3 ubiquitin-protein ligase HECW2

1

6

High-throughput

0.479

High

355315

DUX4
Double homeobox protein 4

1

3

High-throughput

0.479

High

355316

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

355318

ING1
Inhibitor of growth protein 1

1

10

Small-scale

0.479

High

355319

IKZF3
Zinc finger protein Aiolos

1

7

High-throughput

0.479

High

128703

MEN1
Menin

1

0

High-throughput

0.458

High

285553

BAF
Barrier-to-autointegration factor

1

0

Small-scale

0.458

High

355149

DDIT3
DNA damage-inducible transcript 3 protein

1

0

Small-scale

0.458

High

355157

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

355165

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

0

High-throughput

0.458

High

355244

LYRIC
Protein LYRIC

1

0

High-throughput

0.458

High

355252

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

355257

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

355309

RIC8B
Chaperone Ric-8B

1

0

High-throughput

0.458

High

355330

SCC4
MAU2 chromatid cohesion factor homolog

1

0

High-throughput

0.458

High

66060

RP1BL
Ras-related protein Rap-1b-like protein

1

7

High-throughput

0.445

High

71808

FOXO6
Forkhead box protein O6

1

2

High-throughput

0.445

High

355125

JUN
Transcription factor Jun

1

5

High-throughput

0.445

High

355135

CFTR
Cystic fibrosis transmembrane conductance regulator

1

4

High-throughput

0.445

High

355209

SNW1
SNW domain-containing protein 1

1

2

High-throughput

0.445

High

355251

MOT11
Monocarboxylate transporter 11

1

3

High-throughput

0.445

High

355283

CDC5L
Cell division cycle 5-like protein

1

2

High-throughput

0.445

High

355287

AN32E
Acidic leucine-rich nuclear phosphoprotein 32 family member E

1

10

Small-scale

0.445

High

355301

LN28A
Protein lin-28 homolog A

1

3

High-throughput

0.445

High

355302

RAB18
Ras-related protein Rab-18

1

3

High-throughput

0.445

High

355320

INT6
Integrator complex subunit 6

1

1

High-throughput

0.445

High

355324

TRI33
E3 ubiquitin-protein ligase TRIM33

1

16

Small-scale

0.445

High

105043

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

255729

USO1
General vesicular transport factor p115

1

17

High-throughput

0.437

High

355212

TRI29
Tripartite motif-containing protein 29

1

9

Small-scale

0.437

High

355237

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

355292

RAB1B
Ras-related protein Rab-1B

1

2

High-throughput

0.437

High

355322

HECD1
E3 ubiquitin-protein ligase HECTD1

1

10

High-throughput

0.437

High

355327

FND3A
Fibronectin type-III domain-containing protein 3A

1

6

High-throughput

0.437

High

355274

ARHGQ
Rho guanine nucleotide exchange factor 26

1

7

High-throughput

0.407

High

355182

ERF1
Eukaryotic peptide chain release factor subunit 1

1

0

High-throughput

0.249

Low

355310

GFOD1
Glucose-fructose oxidoreductase domain-containing protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025