Interactor 1: CBX4 (O00257)
E3 SUMO-protein ligase CBX4 (EC 2.3.2.-) (Chromobox protein homolog 4) (Polycomb 2 homolog) (Pc2) (hPc2)
Gene: CBX4

Interactor 2: PCGF6 (Q9BYE7)
Polycomb group RING finger protein 6 (Mel18 and Bmi1-like RING finger) (RING finger protein 134)
Gene: PCGF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.909

The method score is based on:

Property Details
Experiments 27705803, 28514442, 33961781, 21282530
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CBX7_C~RAWUL
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0031519 - PcG protein complex
GO:0035102 - PRC1 complex
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 560
Hs

1 350
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Last updated: 15 Jul 2024