Protein: BACH
Cytosolic acyl coenzyme A thioester hydrolase (EC 3.1.2.2) (Acyl-CoA thioesterase 7) (Brain acyl-CoA hydrolase) (BACH) (hBACH) (CTE-IIa) (CTE-II) (Long chain acyl-CoA thioester hydrolase)

Gene: BACH, ACOT7
Organism: Homo sapiens
Interactions: 177
UniProt ID: O00154

Gene Ontology (top 5):
GO:0000062 - fatty-acyl-CoA binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

123416

ACO12
Acetyl-coenzyme A thioesterase

2

7

High-throughput

0.783

High

123454

UBQL1
Ubiquilin-1

3

1

High-throughput

0.675

High

123443

CB39L
Calcium-binding protein 39-like

3

1

High-throughput

0.656

High

123449

THAP1
THAP domain-containing protein 1

3

0

High-throughput

0.646

High

123420

TR19L
Tumor necrosis factor receptor superfamily member 19L

3

0

High-throughput

0.638

High

123457

FBW1A
F-box/WD repeat-containing protein 1A

2

1

High-throughput

0.628

High

123290

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

7

High-throughput

0.618

High

123343

MAGA6
Melanoma-associated antigen 6

3

3

High-throughput

0.616

High

123381

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

2

0

High-throughput

0.612

High

123452

UBQL2
Ubiquilin-2

2

1

High-throughput

0.606

High

123359

PKNX1
Homeobox protein PKNOX1

2

0

High-throughput

0.602

High

104688

F6VUV4
Dehydrogenase/reductase 4 like 2

3

1

High-throughput

0.585

High

123303

BAG4
BAG family molecular chaperone regulator 4

2

0

High-throughput

0.580

High

123371

UBXN1
UBX domain-containing protein 1

2

0

High-throughput

0.580

High

123390

DAZP2
DAZ-associated protein 2

2

0

High-throughput

0.580

High

123404

ZN438
Zinc finger protein 438

2

0

High-throughput

0.580

High

123437

SPC1L
Speriolin-like protein

2

0

High-throughput

0.580

High

123410

SH2D3
SH2 domain-containing protein 3C

2

2

High-throughput

0.571

High

123389

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

2

0

High-throughput

0.559

High

123342

MAGA3
Melanoma-associated antigen 3

2

3

High-throughput

0.553

High

123387

PO6F1
POU domain, class 6, transcription factor 1

2

1

High-throughput

0.553

High

123399

DR4L2
Dehydrogenase/reductase SDR family member 4-like 2

2

2

High-throughput

0.552

High

123349

FXR1
RNA-binding protein FXR1

1

1

High-throughput

0.541

High

123426

RHG07
Rho GTPase-activating protein 7

1

1

High-throughput

0.541

High

123306

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.536

High

123374

FMR1
Fragile X messenger ribonucleoprotein 1

1

1

High-throughput

0.536

High

123382

CUL3
Cullin-3

1

1

High-throughput

0.536

High

123383

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

2

High-throughput

0.536

High

123393

MYLK
Myosin light chain kinase, smooth muscle

1

1

High-throughput

0.536

High

123460

SAR1B
Small COPII coat GTPase SAR1B

1

2

High-throughput

0.536

High

123353

TERF1
Telomeric repeat-binding factor 1

1

0

High-throughput

0.529

High

123434

TINF2
TERF1-interacting nuclear factor 2

1

0

High-throughput

0.529

High

123448

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.529

High

123461

V9HW27
Alpha-crystallin B chain

1

1

High-throughput

0.515

High

123294

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

High-throughput

0.513

High

123300

RA51D
DNA repair protein RAD51 homolog 4

1

0

High-throughput

0.513

High

123329

RS4Y1
Small ribosomal subunit protein eS4, Y isoform 1

1

0

High-throughput

0.513

High

123369

ANK2
Ankyrin-2

1

0

High-throughput

0.513

High

123431

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.513

High

123435

KPCD2
Serine/threonine-protein kinase D2

1

0

High-throughput

0.513

High

123441

RNF41
E3 ubiquitin-protein ligase NRDP1

1

0

High-throughput

0.513

High

123445

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

0

High-throughput

0.513

High

123453

CAPS1
Calcium-dependent secretion activator 1

1

0

High-throughput

0.513

High

123352

ATX1
Ataxin-1

1

2

High-throughput

0.508

High

123362

CDC42
Cell division control protein 42 homolog

1

4

High-throughput

0.501

High

123347

HXA1
Homeobox protein Hox-A1

1

3

High-throughput

0.494

High

123337

DCTD
Deoxycytidylate deaminase

1

0

High-throughput

0.493

High

123309

CRYAB
Alpha-crystallin B chain

1

1

High-throughput

0.481

High

123318

ATX1L
Ataxin-1-like

1

2

High-throughput

0.481

High

123297

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.479

High

123307

AATM
Aspartate aminotransferase, mitochondrial

1

1

High-throughput

0.479

High

123313

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.479

High

123315

LA
Lupus La protein

1

1

High-throughput

0.479

High

123316

ANXA2
Annexin A2

1

1

High-throughput

0.479

High

123317

ANXA5
Annexin A5

1

1

High-throughput

0.479

High

123322

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

123325

AATC
Aspartate aminotransferase, cytoplasmic

1

1

High-throughput

0.479

High

123334

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

123338

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

123340

BRCA1
Breast cancer type 1 susceptibility protein

1

2

High-throughput

0.479

High

123341

COIL
Coilin

1

1

High-throughput

0.479

High

123344

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.479

High

123346

TCPG
T-complex protein 1 subunit gamma

1

2

High-throughput

0.479

High

123348

TCPD
T-complex protein 1 subunit delta

1

2

High-throughput

0.479

High

123354

RD23B
UV excision repair protein RAD23 homolog B

1

2

High-throughput

0.479

High

123360

HDAC4
Histone deacetylase 4

1

2

High-throughput

0.479

High

123365

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

123368

RHOG
Rho-related GTP-binding protein RhoG

1

4

High-throughput

0.479

High

123375

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

1

High-throughput

0.479

High

123376

DUS4
Dual specificity protein phosphatase 4

1

2

High-throughput

0.479

High

123379

TCOF
Treacle protein

1

1

High-throughput

0.479

High

123380

SQSTM
Sequestosome-1

1

1

High-throughput

0.479

High

123396

EXOS6
Exosome complex component MTR3

1

1

High-throughput

0.479

High

123402

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

123405

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

1

High-throughput

0.479

High

123413

DUS19
Dual specificity protein phosphatase 19

1

2

High-throughput

0.479

High

123415

ASB11
Ankyrin repeat and SOCS box protein 11

1

1

High-throughput

0.479

High

123427

EFGM
Elongation factor G, mitochondrial

1

1

High-throughput

0.479

High

123430

NECD
Necdin

1

3

High-throughput

0.479

High

123433

TCPH
T-complex protein 1 subunit eta

1

2

High-throughput

0.479

High

123439

ATX3L
Ataxin-3-like protein

1

1

High-throughput

0.479

High

123440

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

123451

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

123311

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.460

High

123444

NCOA5
Nuclear receptor coactivator 5

1

0

High-throughput

0.460

High

123291

NFIB
Nuclear factor 1 B-type

1

0

High-throughput

0.458

High

123292

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

0

High-throughput

0.458

High

123293

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

0

High-throughput

0.458

High

123295

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.458

High

123296

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.458

High

123299

TBCA
Tubulin-specific chaperone A

1

0

High-throughput

0.458

High

123301

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.458

High

123302

ERLN2
Erlin-2

1

0

High-throughput

0.458

High

123305

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.458

High

123308

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

123310

K1C14
Keratin, type I cytoskeletal 14

1

0

High-throughput

0.458

High

123314

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

123321

DESP
Desmoplakin

1

0

High-throughput

0.458

High

123324

PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

1

0

High-throughput

0.458

High

123326

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

123327

ITB5
Integrin beta-5

1

0

High-throughput

0.458

High

123330

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

0

High-throughput

0.458

High

123331

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.458

High

123332

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

123333

PSA1
Proteasome subunit alpha type-1

1

0

High-throughput

0.458

High

123335

PRDX6
Peroxiredoxin-6

1

0

High-throughput

0.458

High

123336

PPIF
Peptidyl-prolyl cis-trans isomerase F, mitochondrial

1

0

High-throughput

0.458

High

123339

TALDO
Transaldolase

1

0

High-throughput

0.458

High

123345

NASP
Nuclear autoantigenic sperm protein

1

0

High-throughput

0.458

High

123350

GDIR2
Rho GDP-dissociation inhibitor 2

1

0

High-throughput

0.458

High

123351

COPB
Coatomer subunit beta

1

0

High-throughput

0.458

High

123356

KAD2
Adenylate kinase 2, mitochondrial

1

0

High-throughput

0.458

High

123357

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

0

High-throughput

0.458

High

123363

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.458

High

123366

RS14
Small ribosomal subunit protein uS11

1

0

High-throughput

0.458

High

123367

ERF1
Eukaryotic peptide chain release factor subunit 1

1

0

High-throughput

0.458

High

123372

UBE3A
Ubiquitin-protein ligase E3A

1

0

High-throughput

0.458

High

123377

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

123385

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

0

High-throughput

0.458

High

123386

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.458

High

123388

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.458

High

123391

SYK
Lysine--tRNA ligase

1

0

High-throughput

0.458

High

123392

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.458

High

123394

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

123400

KDM7A
Lysine-specific demethylase 7A

1

0

High-throughput

0.458

High

123406

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

123412

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

123414

PCNP
PEST proteolytic signal-containing nuclear protein

1

0

High-throughput

0.458

High

123417

TOPB1
DNA topoisomerase 2-binding protein 1

1

0

High-throughput

0.458

High

123418

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

123422

FUBP1
Far upstream element-binding protein 1

1

0

High-throughput

0.458

High

123423

PHIPL
Phytanoyl-CoA hydroxylase-interacting protein-like

1

0

High-throughput

0.458

High

123428

FNBP1
Formin-binding protein 1

1

0

High-throughput

0.458

High

123429

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

0

High-throughput

0.458

High

123432

ACON
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.458

High

123442

SFXN1
Sideroflexin-1

1

0

High-throughput

0.458

High

123446

OLA1
Obg-like ATPase 1

1

0

High-throughput

0.458

High

123456

SYFA
Phenylalanine--tRNA ligase alpha subunit

1

0

High-throughput

0.458

High

123459

YTHD2
YTH domain-containing family protein 2

1

0

High-throughput

0.458

High

123355

EPHA4
Ephrin type-A receptor 4

1

1

High-throughput

0.457

High

123298

GSDME
Gasdermin-E

1

1

High-throughput

0.445

High

123319

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.445

High

123320

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.445

High

123397

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.445

High

123419

LPAR1
Lysophosphatidic acid receptor 1

1

1

High-throughput

0.445

High

123304

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

123398

RETST
All-trans-retinol 13,14-reductase

1

1

High-throughput

0.437

High

123403

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

123458

TBL2
Transducin beta-like protein 2

1

1

High-throughput

0.437

High

123312

FIBG
Fibrinogen gamma chain

1

0

High-throughput

0.426

High

123323

ANFB
Natriuretic peptides B

1

0

High-throughput

0.426

High

123328

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

0

High-throughput

0.426

High

123358

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.426

High

123364

SMS
Somatostatin

1

0

Small-scale

0.426

High

123378

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.426

High

123384

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

123409

DND1
Dead end protein homolog 1

1

0

High-throughput

0.426

High

123424

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.426

High

123425

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

0

High-throughput

0.426

High

123436

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

123447

DDX28
Probable ATP-dependent RNA helicase DDX28

1

0

High-throughput

0.426

High

123455

GAB2
GRB2-associated-binding protein 2

1

0

High-throughput

0.426

High

85428

B7ZBJ6
Calcium binding protein 39 like

1

1

High-throughput

0.407

High

123438

ENKD1
Enkurin domain-containing protein 1

2

0

High-throughput

0.316

High

123370

CAV1
Caveolin-1

2

0

High-throughput

0.298

High

123373

KDSR
3-ketodihydrosphingosine reductase

1

0

High-throughput

0.279

Low

123401

FOXI2
Forkhead box protein I2

1

0

High-throughput

0.279

Low

85212

RBG10
Rab GTPase-activating protein 1-like, isoform 10

1

0

High-throughput

0.249

Low

104796

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

123361

CU058
Uncharacterized protein C21orf58

1

0

High-throughput

0.249

Low

123407

PNM8A
Paraneoplastic antigen-like protein 8A

1

0

High-throughput

0.249

Low

123408

MGDP1
Magnesium-dependent phosphatase 1

1

0

High-throughput

0.249

Low

123421

C102A
Coiled-coil domain-containing protein 102A

1

0

High-throughput

0.249

Low

123450

RRBP1
Ribosome-binding protein 1

1

0

High-throughput

0.249

Low

123395

RBG1L
Rab GTPase-activating protein 1-like

1

0

High-throughput

0.232

Low

123411

TTC9C
Tetratricopeptide repeat protein 9C

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025