HitPredict

Interactor 1: NIN (Q8N4C6)
Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein)
Gene: NIN

Interactor 2: CYLD (Q9NQC7)
Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)
Gene: CYLD

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28718761
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 2090 Hs			1 956
+	Hs
		725251 MYH10_HUMAN (12-1201): 4.09e-38: 159: 12.98		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		725032 MYH9_HUMAN (37-778): 5.44e-23: 110: 11.55		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		1068673 PLEC_HUMAN (320-1163): 1.13e-15: 86.3: 13.21		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		551848 DESP_HUMAN (1122-2071): 1.98e-15: 85.1: 11.54		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		1343369 MYH13_HUMAN (1382-2076): 5.15e-14: 80.5: 14.35		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		1309827 FYCO1_HUMAN (365-1097): 5.65e-13: 77.1: 18.63		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		254517 ROCK2_HUMAN (367-978): 1.13e-12: 75.9: 17.50		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		1343396 NINL_HUMAN (1044-2050): 5.99e-09: 63.9: 9.93		CYLD_HUMAN (1-956): 0: 1872: 100.00