HitPredict

Interactor 1: MINK1 (Q8N4C8)
Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)
Gene: MINK1

Interactor 2: STRN4 (Q9NRL3)
Striatin-4 (Zinedin)
Gene: STRN4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.681

Property	Details
Experiments	32640226, 33961781, 32707033
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0030425 - dendrite
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1332 Hs			1 753
+	Hs
		1022840 MINK1_HUMAN (1-1332): 0: 1277: 100.00		STRN3_HUMAN (22-753): 8.07e-152: 463: 48.27
+	Hs
		215251 MINK1_HUMAN (1-1332): 0: 1277: 100.00		STRN_HUMAN (36-753): 8.04e-148: 452: 47.92
+	Hs
		1344920 TNIK_HUMAN (1-1332): 0: 1098: 60.83		STRN4_HUMAN (1-753): 0: 566: 100.00
+	Mm
		885679 TNIK_MOUSE (1-1332): 0: 1112: 62.60		STRN4_MOUSE (1-753): 3.92e-177: 527: 94.21
+	Mm
		949415 TNIK_MOUSE (1-1332): 0: 1112: 62.60		STRN3_MOUSE (29-753): 1.18e-158: 481: 49.01
+	Hs
		324890 M4K4_HUMAN (1-1332): 0: 1026: 57.14		STRN4_HUMAN (1-753): 0: 566: 100.00
+	Mm
		223076 TNIK_MOUSE (1-1332): 0: 1112: 62.60		STRN_MOUSE (36-753): 1.45e-147: 452: 48.05
+	Hs
		1022881 TNIK_HUMAN (1-1332): 0: 1098: 60.83		STRN3_HUMAN (22-753): 8.07e-152: 463: 48.27
+	Hs
		215286 TNIK_HUMAN (1-1332): 0: 1098: 60.83		STRN_HUMAN (36-753): 8.04e-148: 452: 47.92
+	Hs
		91410 E7EN19_HUMAN (1-1332): 0: 1031: 58.54		STRN3_HUMAN (22-753): 8.07e-152: 463: 48.27
+	Hs
		324798 M4K4_HUMAN (1-1332): 0: 1026: 57.14		STRN3_HUMAN (22-753): 8.07e-152: 463: 48.27
+	Hs
		91407 E7EN19_HUMAN (1-1332): 0: 1031: 58.54		STRN_HUMAN (36-753): 8.04e-148: 452: 47.92
+	Hs
		215181 M4K4_HUMAN (1-1332): 0: 1026: 57.14		STRN_HUMAN (36-753): 8.04e-148: 452: 47.92
+	Hs
		793038 TNIK_HUMAN (1-1332): 0: 1098: 60.83		LIS1_HUMAN (587-753): 8.84e-47: 173: 22.75
+	Mm
		949357 TNIK_MOUSE (1-1332): 0: 1112: 62.60		TBL1R_MOUSE (29-521): 1e-34: 141: 10.52
+	Hs
		324857 M4K4_HUMAN (1-1332): 0: 1026: 57.14		FBXW7_HUMAN (467-752): 2.04e-62: 224: 15.03
+	Hs
		1022814 STK3_HUMAN (3-507): 3.96e-120: 384: 30.12		STRN3_HUMAN (22-753): 8.07e-152: 463: 48.27
+	Hs
		215226 STK3_HUMAN (3-507): 3.96e-120: 384: 30.12		STRN_HUMAN (36-753): 8.04e-148: 452: 47.92
+	Dm
		87978 Q7KV89_DROME (3-759): 6.63e-122: 408: 42.76		D3DML3_DROME (56-753): 3.12e-127: 398: 44.01
+	Dm
		87984 Q9VEN3_DROME (13-347): 4.85e-119: 387: 42.73		D3DML3_DROME (56-753): 3.12e-127: 398: 44.01