HitPredict

Interactor 1: PCD20 (Q8N6Y1)
Protocadherin-20 (Protocadherin-13)
Gene: PCDH20

Interactor 2: PTPRU (Q92729)
Receptor-type tyrosine-protein phosphatase U (R-PTP-U) (EC 3.1.3.48) (Pancreatic carcinoma phosphatase 2) (PCP-2) (Protein-tyrosine phosphatase J) (PTP-J) (hPTP-J) (Protein-tyrosine phosphatase pi) (PTP pi) (Protein-tyrosine phosphatase receptor omicron) (PTP-RO) (Receptor-type protein-tyrosine phosphatase psi) (R-PTP-psi)
Gene: PTPRU

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007155 - cell adhesion
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 951 Hs			1 1446
+	Hs
		225515 PCDH7_HUMAN (68-919): 0: 703: 30.80		PTPRA_HUMAN (673-1443): 0: 755: 28.46
+	Hs
		1269198 PCDGD_HUMAN (537-951): 8.4e-67: 243: 23.84		PTPRU_HUMAN (1-1446): 0: 1131: 100.00
+	Hs
		1069995 PCDGD_HUMAN (537-951): 8.4e-67: 243: 23.84		PTPRK_HUMAN (26-1442): 0: 1098: 59.48
+	Hs
		1269189 PCDGG_HUMAN (2-312): 9.42e-33: 138: 17.96		PTPRU_HUMAN (1-1446): 0: 1131: 100.00
+	Hs
		1069992 PCDGG_HUMAN (2-312): 9.42e-33: 138: 17.96		PTPRK_HUMAN (26-1442): 0: 1098: 59.48
+	Hs
		1269197 PCDGM_HUMAN (581-830): 2.73e-14: 79.3: 28.30		PTPRU_HUMAN (1-1446): 0: 1131: 100.00
+	Hs
		617034 PCDB1_HUMAN (212-919): 2.87e-143: 448: 23.10		PTPRD_HUMAN (187-963): 3.95e-39: 162: 10.28
+	Hs
		490044 PCDGD_HUMAN (537-951): 8.4e-67: 243: 23.84		PTPRF_HUMAN (7-941): 1.88e-67: 254: 11.64
+	Hs
		616996 PCD20_HUMAN (411-951): 8.83e-99: 333: 21.38		PTPRD_HUMAN (187-963): 3.95e-39: 162: 10.28
+	Hs
		490028 PCDBG_HUMAN (4-457): 4.93e-60: 221: 16.27		PTPRF_HUMAN (7-941): 1.88e-67: 254: 11.64
+	Hs
		617033 PCDB6_HUMAN (539-951): 1.58e-70: 251: 20.82		PTPRD_HUMAN (187-963): 3.95e-39: 162: 10.28
+	Hs
		617035 PCDG6_HUMAN (538-950): 3.48e-67: 244: 22.25		PTPRD_HUMAN (187-963): 3.95e-39: 162: 10.28
+	Hs
		1032046 PCDGD_HUMAN (537-951): 8.4e-67: 243: 23.84		PTPRS_HUMAN (187-943): 1.73e-38: 160: 10.32
+	Hs
		617023 PCDBG_HUMAN (4-457): 4.93e-60: 221: 16.27		PTPRD_HUMAN (187-963): 3.95e-39: 162: 10.28
+	Hs
		1032047 PCDG7_HUMAN (543-879): 1.34e-57: 216: 22.32		PTPRS_HUMAN (187-943): 1.73e-38: 160: 10.32
+	Hs
		490019 PCDC1_HUMAN (573-810): 2.2e-18: 92.8: 31.05		PTPRF_HUMAN (7-941): 1.88e-67: 254: 11.64
+	Hs
		617032 PCDGG_HUMAN (2-312): 9.42e-33: 138: 17.96		PTPRD_HUMAN (187-963): 3.95e-39: 162: 10.28