HitPredict

Interactor 1: ZFP41 (Q8N8Y5)
Zinc finger protein 41 homolog (Zfp-41)
Gene: ZFP41

Interactor 2: NOTC3 (Q9UM47)
Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain]
Gene: NOTCH3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 198 Hs			1 2321
+	Hs
		980426 ZSCA2_HUMAN (2-197): 6.84e-102: 307: 33.99		NOTC2_HUMAN (584-1691): 1.87e-117: 419: 26.15
+	Hs
		980462 ZN397_HUMAN (28-198): 7.29e-96: 289: 40.11		NOTC2_HUMAN (584-1691): 1.87e-117: 419: 26.15
+	Hs
		980451 ZFP41_HUMAN (1-198): 1.1e-92: 270: 100.00		NOTC2_HUMAN (584-1691): 1.87e-117: 419: 26.15
+	Hs
		980477 ZN480_HUMAN (19-198): 1.97e-83: 258: 36.90		NOTC2_HUMAN (584-1691): 1.87e-117: 419: 26.15
+	Hs
		563705 ZKSC1_HUMAN (5-197): 5.16e-73: 231: 38.19		NOTC2_HUMAN (584-1691): 1.87e-117: 419: 26.15
+	Hs
		980472 ZN431_HUMAN (30-198): 1.55e-72: 231: 39.43		NOTC2_HUMAN (584-1691): 1.87e-117: 419: 26.15
+	Hs
		485343 GLI4_HUMAN (3-196): 1.15e-68: 215: 36.32		NOTC2_HUMAN (584-1691): 1.87e-117: 419: 26.15
+	Hs
		980554 ZN358_HUMAN (1-139): 2.59e-65: 212: 21.23		NOTC2_HUMAN (584-1691): 1.87e-117: 419: 26.15
+	Hs
		980539 ZN430_HUMAN (67-198): 1.17e-57: 192: 42.42		NOTC2_HUMAN (584-1691): 1.87e-117: 419: 26.15
+	Hs
		980446 ZN664_HUMAN (87-198): 1.57e-25: 100: 48.21		NOTC2_HUMAN (584-1691): 1.87e-117: 419: 26.15
+	Hs
		980566 ZN629_HUMAN (1-194): 1.09e-23: 99.6: 15.18		NOTC2_HUMAN (584-1691): 1.87e-117: 419: 26.15
+	Hs
		1219780 ZNF34_HUMAN (6-198): 3.17e-79: 247: 36.00		ANKH1_HUMAN (1565-1993): 3.29e-70: 265: 17.61
+	Hs
		565090 ZNF7_HUMAN (84-139): 4.99e-12: 65.9: 53.57		NOTC2_HUMAN (584-1691): 1.87e-117: 419: 26.15
+	Hs
		254652 ZN623_HUMAN (103-193): 6.58e-12: 65.5: 38.46		NOTC2_HUMAN (584-1691): 1.87e-117: 419: 26.15
+	Hs
		980381 ZKSC8_HUMAN (1-35): 9.66e-12: 64.9: 22.22		NOTC2_HUMAN (584-1691): 1.87e-117: 419: 26.15
+	Hs
		724383 ZFP41_HUMAN (1-198): 1.1e-92: 270: 100.00		FBN2_HUMAN (551-1692): 2.67e-31: 137: 14.76
+	Hs
		724348 ZFP41_HUMAN (1-198): 1.1e-92: 270: 100.00		FBN1_HUMAN (894-1610): 8.7e-17: 90: 15.75
+	Hs
		563640 ZNF24_HUMAN (132-198): 5.65e-13: 68.2: 49.25		DNER_HUMAN (473-544): 4.35e-09: 63.9: 43.68