HitPredict

Interactor 1: LRC57 (Q8N9N7)
Leucine-rich repeat-containing protein 57
Gene: LRRC57

Interactor 2: LRC40 (Q9H9A6)
Leucine-rich repeat-containing protein 40
Gene: LRRC40

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LRR_1~LRR_8, LRR_8~LRR_8
Common GO terms	GO:0016020 - membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 239 Hs			1 602
+	Hs
		1050066 SCRIB_HUMAN (26-239): 1.16e-44: 161: 22.27		LRC40_HUMAN (1-256): 1.44e-25: 113: 21.45
+	Hs
		232877 SCRIB_HUMAN (26-239): 1.16e-44: 161: 22.27		PHLP1_HUMAN (82-555): 7.84e-25: 112: 25.00
+	Dm
		1181694 SCRIB_DROME (30-239): 1.16e-44: 161: 21.30		SCRIB_DROME (460-602): 4.77e-23: 106: 22.92
+	At
		99004 RGI4_ARATH (2-169): 5.65e-26: 107: 25.00		BAME1_ARATH (14-265): 2.92e-34: 141: 21.62
+	At
		1258435 MIK2_ARATH (2-126): 3.85e-27: 110: 21.09		BAME2_ARATH (6-264): 4.36e-33: 137: 21.43
+	At
		99002 RGI4_ARATH (2-169): 5.65e-26: 107: 25.00		RGI4_ARATH (1-236): 5.49e-33: 137: 21.63
+	Hs
		1050046 SCRIB_HUMAN (26-239): 1.16e-44: 161: 22.27		LRRC1_HUMAN (41-220): 2.84e-14: 77.8: 31.11
+	At
		221776 GSO2_ARATH (3-122): 4.41e-22: 96.3: 32.26		BAME1_ARATH (14-265): 2.92e-34: 141: 21.62
+	At
		99021 RGI4_ARATH (2-169): 5.65e-26: 107: 25.00		FLS2_ARATH (4-234): 4.26e-30: 128: 21.81
+	At
		84419 IMK3_ARATH (1-199): 4.21e-31: 122: 21.68		PEPR2_ARATH (336-601): 2.96e-24: 110: 19.19
+	At
		1323503 IMK2_ARATH (98-238): 1.47e-22: 97.8: 20.95		TDR_ARATH (6-279): 9.97e-31: 130: 18.31
+	Gm
		1341216 CLV1B_SOYBN (1-155): 1.19e-22: 98.2: 15.92		CLV1B_SOYBN (21-254): 8.64e-30: 127: 20.25
+	Hs
		1301436 LRRC1_HUMAN (22-231): 4.67e-39: 143: 26.39		ERBIN_HUMAN (83-237): 3.33e-14: 78.2: 31.61
+	Hs
		1301465 ERBIN_HUMAN (2-148): 1.05e-26: 109: 27.21		SHOC2_HUMAN (449-601): 3.56e-20: 96.5: 26.80
+	At
		84412 IMK3_ARATH (1-199): 4.21e-31: 122: 21.68		BAME3_ARATH (332-601): 1.66e-15: 82.3: 17.69
+	At
		99006 RGI4_ARATH (2-169): 5.65e-26: 107: 25.00		BAME3_ARATH (332-601): 1.66e-15: 82.3: 17.69
+	Mm
		1193432 ERBIN_MOUSE (2-148): 2.17e-27: 111: 27.89		ERBIN_MOUSE (198-578): 7.52e-14: 77: 24.48
+	Hs
		1301432 ERBIN_HUMAN (2-148): 1.05e-26: 109: 27.21		ERBIN_HUMAN (83-237): 3.33e-14: 78.2: 31.61