HitPredict

Interactor 1: IQUB (Q8NA54)
IQ motif and ubiquitin-like domain-containing protein
Gene: IQUB

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.80	0.700

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-C3HC4_2
Common GO terms	-
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 791 Hs			1 522
+	Hs
		1020811 IQUB_HUMAN (1-791): 0: 1369: 100.00		TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85
+	Hs
		536932 IQUB_HUMAN (1-791): 0: 1369: 100.00		TRI27_HUMAN (57-404): 7.01e-43: 161: 12.90
+	Hs
		1204895 IQUB_HUMAN (1-791): 0: 1369: 100.00		TRI50_HUMAN (60-403): 1.01e-39: 152: 14.12