HitPredict

Interactor 1: ZNT6 (Q6NXT4)
Zinc transporter 6 (ZnT-6) (Solute carrier family 30 member 6)
Gene: SLC30A6

Interactor 2: ZNT5 (Q8TAD4)
Proton-coupled zinc antiporter SLC30A5 (Solute carrier family 30 member 5) (Zinc transporter 5) (ZnT-5) (ZnT-like transporter 1) (hZTL1)
Gene: SLC30A5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.935

The method score is based on:

Property Details
Experiments 21402707, 35271311, 25657003, 19759014, 15994300, unassigned3795
Identification Methods affinity chromatography technology, bimolecular fluorescence complementation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cation_efflux~Cation_efflux
Common GO terms GO:0005385 - zinc ion transmembrane transporter activity
GO:0005794 - Golgi apparatus
GO:0006829 - zinc ion transport
GO:0015297 - antiporter activity
GO:0032588 - trans-Golgi network membrane
and 1 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 461
Hs

1 765
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+ Ce

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Last updated: 11Aug2025