Protein: ZNT2
Proton-coupled zinc antiporter SLC30A2 (Solute carrier family 30 member 2) (Zinc transporter 2) (ZnT-2)

Gene: ZNT2, SLC30A2
Organism: Homo sapiens
Interactions: 177
UniProt ID: Q9BRI3

Gene Ontology (top 5):
GO:0005385 - zinc ion transmembrane transporter activity
GO:0005737 - cytoplasm
GO:0005743 - mitochondrial inner membrane
GO:0005765 - lysosomal membrane
GO:0005770 - late endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1406740

ZNT3
Probable proton-coupled zinc antiporter SLC30A3

2

16

Small-scale

0.802

High

1251181

ZNT10
Calcium/manganese antiporter SLC30A10

2

17

Small-scale

0.789

High

580824

PVR
Poliovirus receptor

4

5

High-throughput

0.698

High

1411149

TNR12
Tumor necrosis factor receptor superfamily member 12A

4

0

High-throughput

0.668

High

377897

TNFB
Lymphotoxin-alpha

3

2

High-throughput

0.654

High

1329437

KASH5
Protein KASH5

4

1

High-throughput

0.647

High

230414

CREB3
Cyclic AMP-responsive element-binding protein 3

2

2

High-throughput

0.640

High

561044

CCL4
C-C motif chemokine 4

4

3

High-throughput

0.637

High

166401

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

16

Small-scale

0.618

High

1411135

ZNT2
Proton-coupled zinc antiporter SLC30A2

1

15

Small-scale

0.618

High

1411172

ZNT1
Proton-coupled zinc antiporter SLC30A1

1

15

Small-scale

0.618

High

1411141

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

3

4

High-throughput

0.609

High

194740

FFAR2
Free fatty acid receptor 2

2

18

High-throughput

0.606

High

194849

KCNN4
Intermediate conductance calcium-activated potassium channel protein 4

2

3

High-throughput

0.606

High

549871

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

3

High-throughput

0.606

High

570764

LYAM1
L-selectin

2

4

High-throughput

0.606

High

593695

BGAL
Beta-galactosidase

2

4

High-throughput

0.606

High

683326

TNR5
Tumor necrosis factor receptor superfamily member 5

2

4

High-throughput

0.606

High

706049

CXB2
Gap junction beta-2 protein

2

14

High-throughput

0.606

High

722592

CTR1
High affinity cationic amino acid transporter 1

2

1

High-throughput

0.606

High

770908

OPRM
Mu-type opioid receptor

2

9

High-throughput

0.606

High

783020

CXA5
Gap junction alpha-5 protein

2

14

High-throughput

0.606

High

832649

AQP2
Aquaporin-2

2

3

High-throughput

0.606

High

1132576

FXYD3
FXYD domain-containing ion transport regulator 3

2

1

High-throughput

0.606

High

1186032

SOAT
Sodium-dependent organic anion transporter

2

1

High-throughput

0.606

High

1281189

CPLX4
Complexin-4

2

1

High-throughput

0.606

High

1325356

GLT15
Polypeptide N-acetylgalactosaminyltransferase 15

2

20

High-throughput

0.606

High

1348906

PLPR1
Phospholipid phosphatase-related protein type 1

2

2

High-throughput

0.606

High

1411142

FXYD6
FXYD domain-containing ion transport regulator 6

2

1

High-throughput

0.606

High

1411148

AT131
Endoplasmic reticulum transmembrane helix translocase

2

6

High-throughput

0.606

High

1411150

S39A2
Zinc transporter ZIP2

2

4

High-throughput

0.606

High

1411158

GPC5D
G-protein coupled receptor family C group 5 member D

2

2

High-throughput

0.606

High

1411159

LAT2
Large neutral amino acids transporter small subunit 2

2

1

High-throughput

0.606

High

1411169

LYVE1
Lymphatic vessel endothelial hyaluronic acid receptor 1

2

1

High-throughput

0.606

High

1411170

JAM1
Junctional adhesion molecule A

2

7

High-throughput

0.606

High

184220

RER1
Protein RER1

2

1

High-throughput

0.601

High

243824

ADCY3
Adenylate cyclase type 3

2

3

High-throughput

0.601

High

1043232

TAP2
Antigen peptide transporter 2

2

6

High-throughput

0.601

High

1103579

PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B

2

4

High-throughput

0.601

High

1212294

TM63B
Mechanosensitive cation channel TMEM63B

2

5

High-throughput

0.601

High

1411140

S12A9
Solute carrier family 12 member 9

2

2

High-throughput

0.601

High

1411143

METL9
Protein-L-histidine N-pros-methyltransferase

3

5

High-throughput

0.587

High

156566

C56D2
Transmembrane reductase CYB561D2

2

0

High-throughput

0.580

High

571789

FPPS
Farnesyl pyrophosphate synthase

2

0

High-throughput

0.580

High

761164

EVI2B
Protein EVI2B

2

0

High-throughput

0.580

High

932759

EMP3
Epithelial membrane protein 3

2

0

High-throughput

0.580

High

1205536

M4A13
Membrane-spanning 4-domains subfamily A member 13

2

0

High-throughput

0.580

High

1411154

S38A7
Sodium-coupled neutral amino acid transporter 7

2

0

High-throughput

0.580

High

1411157

TA2R5
Taste receptor type 2 member 5

2

0

High-throughput

0.580

High

1411168

CIA30
Complex I intermediate-associated protein 30, mitochondrial

2

0

High-throughput

0.580

High

1065911

Q08AM2
ADAM33 protein

2

6

High-throughput

0.558

High

66536

PCX2
Pecanex-like protein 2

2

3

High-throughput

0.553

High

139973

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

2

3

High-throughput

0.553

High

335262

CXB5
Gap junction beta-5 protein

2

14

High-throughput

0.553

High

926836

VMAT1
Chromaffin granule amine transporter

2

6

High-throughput

0.553

High

1048274

HGFA
Hepatocyte growth factor activator serine protease

2

1

High-throughput

0.553

High

1109029

AQP6
Aquaporin-6

2

3

High-throughput

0.553

High

1195266

TM52B
Transmembrane protein 52B

2

1

High-throughput

0.553

High

1329975

GP161
G-protein coupled receptor 161

2

5

High-throughput

0.553

High

1394441

SC22A
Vesicle-trafficking protein SEC22a

2

1

High-throughput

0.553

High

1411144

TMM60
Transmembrane protein 60

2

1

High-throughput

0.553

High

48763

ESYT2
Extended synaptotagmin-2

2

5

High-throughput

0.552

High

1085469

SRBP2
Sterol regulatory element-binding protein 2

2

3

High-throughput

0.552

High

1353082

PIGO
GPI ethanolamine phosphate transferase 3, catalytic subunit

2

5

High-throughput

0.549

High

1396396

F210B
Protein FAM210B, mitochondrial

2

2

High-throughput

0.549

High

190636

MRP4
ATP-binding cassette sub-family C member 4

1

4

High-throughput

0.536

High

190686

MRP5
ATP-binding cassette sub-family C member 5

1

4

High-throughput

0.536

High

320492

TM63A
Mechanosensitive cation channel TMEM63A

1

5

High-throughput

0.536

High

537805

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.536

High

931084

HSP72
Heat shock-related 70 kDa protein 2

1

1

High-throughput

0.536

High

1127858

ERG1
Squalene monooxygenase

1

2

High-throughput

0.536

High

1212499

MRP7
ATP-binding cassette sub-family C member 10

1

5

High-throughput

0.536

High

1276290

ATG9A
Autophagy-related protein 9A

1

1

High-throughput

0.536

High

1329186

S15A4
Solute carrier family 15 member 4

1

2

High-throughput

0.536

High

1411136

ESYT1
Extended synaptotagmin-1

1

5

High-throughput

0.536

High

1411160

KCNG1
Voltage-gated potassium channel regulatory subunit KCNG1

1

3

High-throughput

0.536

High

1411166

FND3A
Fibronectin type-III domain-containing protein 3A

1

4

High-throughput

0.536

High

1340709

CC4L
C-C motif chemokine 4-like

1

3

High-throughput

0.523

High

193443

GPR42
G-protein coupled receptor 42

1

19

High-throughput

0.515

High

1116641

I10R1
Interleukin-10 receptor subunit alpha

1

3

High-throughput

0.515

High

1233698

Q6IBD0
CAMPATH-1 antigen

1

1

High-throughput

0.515

High

420040

B3A2
Anion exchange protein 2

1

0

High-throughput

0.513

High

320296

TMCC1
Transmembrane and coiled-coil domains protein 1

2

5

High-throughput

0.504

High

1187188

IPIL2
Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2

2

1

High-throughput

0.504

High

1092387

TSN31
Tetraspanin-31

1

0

High-throughput

0.493

High

1208113

RNFT1
E3 ubiquitin-protein ligase RNFT1

1

11

High-throughput

0.489

High

1248652

LCLT1
Lysocardiolipin acyltransferase 1

1

3

High-throughput

0.489

High

1293995

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

1

High-throughput

0.489

High

1411071

PIGQ
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q

1

1

High-throughput

0.489

High

528711

PPGB
Lysosomal protective protein

1

2

High-throughput

0.481

High

725822

CD52
CAMPATH-1 antigen

1

1

High-throughput

0.481

High

779728

MOT8
Monocarboxylate transporter 8

1

5

High-throughput

0.481

High

1312121

TARG1
Trafficking regulator of GLUT4 1

1

3

High-throughput

0.481

High

1350295

C99L2
CD99 antigen-like protein 2

1

2

High-throughput

0.481

High

1349404

TM163
Transmembrane protein 163

1

5

Small-scale

0.479

High

63693

A5PKU2
TUSC5 protein

1

3

High-throughput

0.470

High

1202532

Q59EV6
Carboxypeptidase

1

2

High-throughput

0.470

High

1232337

Q6FG55
Lymphotoxin-alpha

1

2

High-throughput

0.470

High

1359310

SSMM1
Serine-rich single-pass membrane protein 1

1

1

High-throughput

0.470

High

979180

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.458

High

3501

A0A0S2Z5R8
CD99 antigen-like protein 2

1

2

High-throughput

0.457

High

155252

AGRB1
Adhesion G protein-coupled receptor B1

1

9

High-throughput

0.445

High

296932

DGAT1
Diacylglycerol O-acyltransferase 1

1

1

High-throughput

0.445

High

321780

AGRL1
Adhesion G protein-coupled receptor L1

1

7

High-throughput

0.445

High

326005

UBR5
E3 ubiquitin-protein ligase UBR5

1

7

High-throughput

0.445

High

336762

BAG4
BAG family molecular chaperone regulator 4

1

3

High-throughput

0.445

High

548591

MPRI
Cation-independent mannose-6-phosphate receptor

1

5

High-throughput

0.445

High

907837

CLCN7
H(+)/Cl(-) exchange transporter 7

1

1

High-throughput

0.445

High

933954

NR1H2
Oxysterols receptor LXR-beta

1

3

High-throughput

0.445

High

934274

BI1
Bax inhibitor 1

1

2

High-throughput

0.445

High

1043172

TAP1
Antigen peptide transporter 1

1

6

High-throughput

0.445

High

1245410

ZC3HE
Zinc finger CCCH domain-containing protein 14

1

3

High-throughput

0.445

High

1257810

ACD11
Acyl-CoA dehydrogenase family member 11

1

2

High-throughput

0.445

High

1275403

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

4

High-throughput

0.445

High

1324306

GHDC
GH3 domain-containing protein

1

1

High-throughput

0.445

High

1334404

UXS1
UDP-glucuronic acid decarboxylase 1

1

2

High-throughput

0.445

High

1372439

P2RX5
P2X purinoceptor 5

1

1

High-throughput

0.445

High

1411139

TACAN
Transmembrane protein 120A

1

1

High-throughput

0.445

High

1411147

PGAP6
Post-GPI attachment to proteins factor 6

1

1

High-throughput

0.445

High

1411151

AT132
Polyamine-transporting ATPase 13A2

1

6

High-throughput

0.445

High

1411156

KBRS2
NF-kappa-B inhibitor-interacting Ras-like protein 2

1

13

High-throughput

0.445

High

1411163

CHIP
E3 ubiquitin-protein ligase CHIP

1

1

High-throughput

0.445

High

1411164

ENTP4
Ectonucleoside triphosphate diphosphohydrolase 4

1

2

High-throughput

0.445

High

1411171

AGRG1
Adhesion G-protein coupled receptor G1

1

7

High-throughput

0.445

High

386161

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

4

High-throughput

0.439

High

425232

IC1
Plasma protease C1 inhibitor

1

1

High-throughput

0.439

High

1411165

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

7

High-throughput

0.439

High

183865

VGF
Neurosecretory protein VGF [Cleaved into: Neuroendocrine regulatory peptide-1

1

0

High-throughput

0.426

High

226360

SNG1
Synaptogyrin-1

1

0

High-throughput

0.426

High

336274

BRI3
Membrane protein BRI3

1

0

High-throughput

0.426

High

679248

DNJB1
DnaJ homolog subfamily B member 1

1

0

High-throughput

0.426

High

692124

MARK3
MAP/microtubule affinity-regulating kinase 3

1

0

High-throughput

0.426

High

1154822

KCNJ8
ATP-sensitive inward rectifier potassium channel 8

1

0

High-throughput

0.426

High

1209925

PPM1L
Protein phosphatase 1L

1

0

High-throughput

0.426

High

1335568

DGLB
Diacylglycerol lipase-beta

1

0

High-throughput

0.426

High

1411138

STRA6
Receptor for retinol uptake STRA6

1

0

High-throughput

0.426

High

1411153

ZF64B
Zinc finger protein 64

1

0

High-throughput

0.426

High

506653

GPHRB
Golgi pH regulator B

1

1

High-throughput

0.407

High

773614

COPB2
Coatomer subunit beta'

1

9

High-throughput

0.407

High

841441

RBM34
RNA-binding protein 34

1

4

High-throughput

0.407

High

873296

COPD
Coatomer subunit delta

1

2

High-throughput

0.407

High

895285

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

1

1

High-throughput

0.407

High

944318

TMM33
Transmembrane protein 33

1

1

High-throughput

0.407

High

1085375

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

3

High-throughput

0.407

High

1205025

RABL3
Rab-like protein 3

1

11

High-throughput

0.407

High

1291474

RETR3
Reticulophagy regulator 3

1

2

High-throughput

0.407

High

1313224

PLPL6
Patatin-like phospholipase domain-containing protein 6

1

1

High-throughput

0.407

High

1322585

CP4X1
Cytochrome P450 4X1

1

1

High-throughput

0.407

High

1336997

DIK2A
Divergent protein kinase domain 2A

1

2

High-throughput

0.407

High

1337650

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.407

High

1382717

RFT1
Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1

1

1

High-throughput

0.407

High

1411145

PCX3
Pecanex-like protein 3

1

4

High-throughput

0.407

High

1411152

PLCD
1-acyl-sn-glycerol-3-phosphate acyltransferase delta

1

3

High-throughput

0.407

High

1411155

T161A
Transmembrane protein 161A

1

2

High-throughput

0.407

High

1411161

AMFR
E3 ubiquitin-protein ligase AMFR

1

12

High-throughput

0.407

High

1411162

TMCC3
Transmembrane and coiled-coil domain protein 3

1

5

High-throughput

0.407

High

350409

ABHGA
Phosphatidylserine lipase ABHD16A

2

0

High-throughput

0.316

High

1248857

CE046
Uncharacterized protein C5orf46

2

0

High-throughput

0.316

High

1249561

TM107
Transmembrane protein 107

2

0

High-throughput

0.316

High

1256849

GOT1A
Vesicle transport protein GOT1A

2

0

High-throughput

0.316

High

1312814

NRM
Nurim

2

0

High-throughput

0.316

High

1324428

TM86A
Lysoplasmalogenase TMEM86A

2

0

High-throughput

0.316

High

1349100

F174A
Membrane protein FAM174A

2

0

High-throughput

0.316

High

1385804

T4S18
Transmembrane 4 L6 family member 18

2

0

High-throughput

0.316

High

1411137

YIPF2
Protein YIPF2

2

0

High-throughput

0.316

High

1279540

ADCK2
Uncharacterized aarF domain-containing protein kinase 2

1

0

High-throughput

0.279

Low

1357938

DCAKD
Dephospho-CoA kinase domain-containing protein

1

0

High-throughput

0.279

Low

1411167

TMX2
Thioredoxin-related transmembrane protein 2

1

0

High-throughput

0.279

Low

97024

E9PK97
Serpin family G member 1

1

0

High-throughput

0.238

Low

274841

PX11A
Peroxisomal membrane protein 11A

1

0

High-throughput

0.232

Low

378297

IFN21
Interferon alpha-21

1

0

High-throughput

0.232

Low

814851

CUX1
Homeobox protein cut-like 1

1

0

High-throughput

0.232

Low

963973

NPC2
NPC intracellular cholesterol transporter 2

1

0

High-throughput

0.232

Low

1139252

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

0

High-throughput

0.232

Low

1357319

THEM6
Protein THEM6

1

0

High-throughput

0.232

Low

1411146

RPA2
DNA-directed RNA polymerase I subunit RPA2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025