HitPredict

Interactor 1: TXND5 (Q8NBS9)
Thioredoxin domain-containing protein 5 (EC 1.8.4.-) (EC 5.3.4.1) (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Thioredoxin-like protein p46)
Gene: TXNDC5

Interactor 2: DNJB9 (Q9UBS3)
DnaJ homolog subfamily B member 9 (Endoplasmic reticulum DNA J domain-containing protein 4) (ER-resident protein ERdj4) (ERdj4) (Microvascular endothelial differentiation gene 1 protein) (Mdg-1)
Gene: DNAJB9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~Thioredoxin
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005788 - endoplasmic reticulum lumen GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 432 Hs			1 223
+	Hs
		1240432 TXND5_HUMAN (1-432): 2.46e-124: 369: 100.00		DJB11_HUMAN (4-109): 1.65e-44: 154: 42.06
+	Hs
		1220434 TXND5_HUMAN (1-432): 2.46e-124: 369: 100.00		DJC10_HUMAN (6-219): 3.47e-40: 148: 25.33
+	Hs
		1067845 PDIA6_HUMAN (15-338): 8.51e-39: 147: 18.00		DNJB9_HUMAN (1-223): 5.42e-72: 220: 100.00
+	Hs
		532010 PDIA4_HUMAN (16-191): 7.57e-36: 141: 24.29		DNJB9_HUMAN (1-223): 5.42e-72: 220: 100.00
+	Hs
		423379 PDIA1_HUMAN (56-432): 1.58e-28: 119: 16.41		DNJB9_HUMAN (1-223): 5.42e-72: 220: 100.00
+	Hs
		1055322 PDIA5_HUMAN (50-426): 2.22e-44: 163: 16.24		DJB11_HUMAN (4-109): 1.65e-44: 154: 42.06
+	Hs
		1067846 PDIA6_HUMAN (15-338): 8.51e-39: 147: 18.00		DJB11_HUMAN (4-109): 1.65e-44: 154: 42.06
+	Hs
		1067840 PDIA6_HUMAN (15-338): 8.51e-39: 147: 18.00		DJB12_HUMAN (2-177): 4.03e-44: 153: 29.28
+	Hs
		531914 PDIA4_HUMAN (16-191): 7.57e-36: 141: 24.29		DJB14_HUMAN (10-174): 1.47e-46: 159: 31.74
+	Hs
		1067759 PDIA6_HUMAN (15-338): 8.51e-39: 147: 18.00		DJC10_HUMAN (6-219): 3.47e-40: 148: 25.33
+	Hs
		532011 PDIA4_HUMAN (16-191): 7.57e-36: 141: 24.29		DJB11_HUMAN (4-109): 1.65e-44: 154: 42.06
+	Hs
		532000 PDIA4_HUMAN (16-191): 7.57e-36: 141: 24.29		DJB12_HUMAN (2-177): 4.03e-44: 153: 29.28
+	Hs
		532027 PDIA4_HUMAN (16-191): 7.57e-36: 141: 24.29		DJC16_HUMAN (10-135): 4.26e-41: 150: 36.15
+	Hs
		531897 PDIA4_HUMAN (16-191): 7.57e-36: 141: 24.29		DJC10_HUMAN (6-219): 3.47e-40: 148: 25.33
+	Hs
		532013 PDIA4_HUMAN (16-191): 7.57e-36: 141: 24.29		DNJ5B_HUMAN (19-203): 1.4e-43: 146: 27.27
+	Hs
		423304 PDIA1_HUMAN (56-432): 1.58e-28: 119: 16.41		DJB14_HUMAN (10-174): 1.47e-46: 159: 31.74
+	Hs
		423380 PDIA1_HUMAN (56-432): 1.58e-28: 119: 16.41		DJB11_HUMAN (4-109): 1.65e-44: 154: 42.06
+	Hs
		423372 PDIA1_HUMAN (56-432): 1.58e-28: 119: 16.41		DJB12_HUMAN (2-177): 4.03e-44: 153: 29.28
+	Hs
		423398 PDIA1_HUMAN (56-432): 1.58e-28: 119: 16.41		DJC16_HUMAN (10-135): 4.26e-41: 150: 36.15
+	Hs
		423286 PDIA1_HUMAN (56-432): 1.58e-28: 119: 16.41		DJC10_HUMAN (6-219): 3.47e-40: 148: 25.33