Protein: NALP7
NACHT, LRR and PYD domains-containing protein 7 (Nucleotide-binding oligomerization domain protein 12) (PYRIN-containing APAF1-like protein 3)

Gene: NALP7, NLRP7
Organism: Homo sapiens
Interactions: 161
UniProt ID: Q8WX94

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0010955 - negative regulation of protein processing
GO:0019828 - aspartic-type endopeptidase inhibitor activity
GO:0019966 - interleukin-1 binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1360106

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

18

Small-scale

0.653

High

1051398

ZBT16
Zinc finger and BTB domain-containing protein 16

1

0

Small-scale

0.628

High

65491

OOEP
Oocyte-expressed protein homolog

1

5

Small-scale

0.618

High

947389

NALP5
NACHT, LRR and PYD domains-containing protein 5

1

17

Small-scale

0.618

High

1201675

KHDC3
KH domain-containing protein 3

1

5

Small-scale

0.618

High

1360126

NALP2
NACHT, LRR and PYD domains-containing protein 2

1

18

Small-scale

0.618

High

671832

ZA2G
Zinc-alpha-2-glycoprotein

1

2

High-throughput

0.553

High

1360115

LRIG1
Leucine-rich repeats and immunoglobulin-like domains protein 1

1

12

High-throughput

0.553

High

378575

IL1B
Interleukin-1 beta

1

2

Small-scale

0.515

High

712880

CASP1
Caspase-1

1

20

Small-scale

0.515

High

1252594

DEFI8
Differentially expressed in FDCP 8 homolog

1

1

High-throughput

0.489

High

123153

DX39A
ATP-dependent RNA helicase DDX39A

1

3

High-throughput

0.479

High

207602

DHX15
ATP-dependent RNA helicase DHX15

1

3

High-throughput

0.479

High

424237

S10A8
Protein S100-A8

1

7

High-throughput

0.479

High

425831

PCCA
Propionyl-CoA carboxylase alpha chain, mitochondrial

1

2

High-throughput

0.479

High

425937

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

1

High-throughput

0.479

High

428458

RLA2
Large ribosomal subunit protein P2

1

2

High-throughput

0.479

High

428881

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.479

High

445037

S10A9
Protein S100-A9

1

8

High-throughput

0.479

High

447258

NPM
Nucleophosmin

1

2

High-throughput

0.479

High

456810

ANXA2
Annexin A2

1

2

High-throughput

0.479

High

457588

TBB5
Tubulin beta chain

1

3

High-throughput

0.479

High

474860

VIME
Vimentin

1

11

High-throughput

0.479

High

476765

RSSA
Small ribosomal subunit protein uS2

1

1

High-throughput

0.479

High

480866

LEG1
Galectin-1

1

2

High-throughput

0.479

High

508346

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

3

High-throughput

0.479

High

565986

EF2
Elongation factor 2

1

1

High-throughput

0.479

High

573186

KPYM
Pyruvate kinase PKM

1

1

High-throughput

0.479

High

584785

NDKA
Nucleoside diphosphate kinase A

1

3

High-throughput

0.479

High

611928

RL35A
Large ribosomal subunit protein eL33

1

1

High-throughput

0.479

High

615893

RL17
Large ribosomal subunit protein uL22

1

2

High-throughput

0.479

High

650873

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

3

High-throughput

0.479

High

656203

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

3

High-throughput

0.479

High

658302

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

680445

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

1

High-throughput

0.479

High

686308

RL13
Large ribosomal subunit protein eL13

1

1

High-throughput

0.479

High

691287

1433T
14-3-3 protein theta

1

4

High-throughput

0.479

High

701332

GSTM2
Glutathione S-transferase Mu 2

1

3

High-throughput

0.479

High

724608

S10A7
Protein S100-A7

1

8

High-throughput

0.479

High

729595

CASPE
Caspase-14

1

20

High-throughput

0.479

High

732368

PRDX2
Peroxiredoxin-2

1

6

High-throughput

0.479

High

749087

RL9
Large ribosomal subunit protein uL6

1

1

High-throughput

0.479

High

786749

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

4

High-throughput

0.479

High

807511

IF4A3
Eukaryotic initiation factor 4A-III

1

6

High-throughput

0.479

High

809752

RS19
Small ribosomal subunit protein eS19

1

1

High-throughput

0.479

High

842457

RL35
Large ribosomal subunit protein uL29

1

1

High-throughput

0.479

High

859372

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.479

High

859651

RL21
Large ribosomal subunit protein eL21

1

1

High-throughput

0.479

High

859924

RL28
Large ribosomal subunit protein eL28

1

2

High-throughput

0.479

High

880350

RL34
Large ribosomal subunit protein eL34

1

2

High-throughput

0.479

High

898745

RL14
Large ribosomal subunit protein eL14

1

1

High-throughput

0.479

High

953949

IF4A1
Eukaryotic initiation factor 4A-I

1

4

High-throughput

0.479

High

959880

RS3A
Small ribosomal subunit protein eS1

1

1

High-throughput

0.479

High

961786

RL37A
Large ribosomal subunit protein eL43

1

2

High-throughput

0.479

High

967505

RS7
Small ribosomal subunit protein eS7

1

1

High-throughput

0.479

High

967880

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

4

High-throughput

0.479

High

968393

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

4

High-throughput

0.479

High

969335

RS8
Small ribosomal subunit protein eS8

1

1

High-throughput

0.479

High

975832

RL7A
Large ribosomal subunit protein eL8

1

1

High-throughput

0.479

High

978632

RL23A
Large ribosomal subunit protein uL23

1

1

High-throughput

0.479

High

979094

RS6
Small ribosomal subunit protein eS6

1

1

High-throughput

0.479

High

985784

RL11
Large ribosomal subunit protein uL5

1

2

High-throughput

0.479

High

994683

YBOX1
Y-box-binding protein 1

1

2

High-throughput

0.479

High

1013824

RL24
Large ribosomal subunit protein eL24

1

1

High-throughput

0.479

High

1016131

RL19
Large ribosomal subunit protein eL19

1

1

High-throughput

0.479

High

1027622

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

2

High-throughput

0.479

High

1037570

RL18A
Large ribosomal subunit protein eL20

1

1

High-throughput

0.479

High

1057825

RL18
Large ribosomal subunit protein eL18

1

1

High-throughput

0.479

High

1061073

SRSF1
Serine/arginine-rich splicing factor 1

1

3

High-throughput

0.479

High

1062565

DHX9
ATP-dependent RNA helicase A

1

3

High-throughput

0.479

High

1089765

ILF3
Interleukin enhancer-binding factor 3

1

1

High-throughput

0.479

High

1160016

SRSF7
Serine/arginine-rich splicing factor 7

1

4

High-throughput

0.479

High

1204014

FILA2
Filaggrin-2

1

7

High-throughput

0.479

High

1271465

DHX30
ATP-dependent RNA helicase DHX30

1

3

High-throughput

0.479

High

1360107

PSPC1
Paraspeckle component 1

1

1

High-throughput

0.479

High

1360110

DDX17
Probable ATP-dependent RNA helicase DDX17

1

3

High-throughput

0.479

High

1360117

ATX2
Ataxin-2

1

1

High-throughput

0.479

High

1360118

ROAA
Heterogeneous nuclear ribonucleoprotein A/B

1

4

High-throughput

0.479

High

1360119

TBA1C
Tubulin alpha-1C chain

1

6

High-throughput

0.479

High

1360120

DIDO1
Death-inducer obliterator 1

1

3

High-throughput

0.479

High

1360121

TLE6
Transducin-like enhancer protein 6

1

12

Small-scale

0.479

High

1360122

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

1

High-throughput

0.479

High

1360124

RNC
Ribonuclease 3

1

1

High-throughput

0.479

High

1360133

RL36
Large ribosomal subunit protein eL36

1

1

High-throughput

0.479

High

1360136

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

7

High-throughput

0.479

High

1360132

FAF1
FAS-associated factor 1

1

6

Small-scale

0.464

High

141022

NOP56
Nucleolar protein 56

1

0

High-throughput

0.458

High

370343

CYTA
Cystatin-A

1

0

High-throughput

0.458

High

399999

CATA
Catalase

1

0

High-throughput

0.458

High

423683

ARGI1
Arginase-1

1

0

High-throughput

0.458

High

426543

HMGN2
Non-histone chromosomal protein HMG-17

1

0

High-throughput

0.458

High

445989

ENOA
Alpha-enolase

1

0

High-throughput

0.458

High

552658

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

0

High-throughput

0.458

High

612716

RL7
Large ribosomal subunit protein uL30

1

0

High-throughput

0.458

High

717327

PEBP1
Phosphatidylethanolamine-binding protein 1

1

0

High-throughput

0.458

High

810248

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

868565

RL29
Large ribosomal subunit protein eL29

1

0

High-throughput

0.458

High

960186

RL26
Large ribosomal subunit protein uL24

1

0

High-throughput

0.458

High

974953

TYB4
Thymosin beta-4

1

0

High-throughput

0.458

High

1039307

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.458

High

1062274

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

0

High-throughput

0.458

High

1131085

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

0

High-throughput

0.458

High

1247824

PADI6
Inactive protein-arginine deiminase type-6

1

0

Small-scale

0.458

High

1360108

DGCR8
Microprocessor complex subunit DGCR8

1

0

High-throughput

0.458

High

1360114

ZBED3
Zinc finger BED domain-containing protein 3

1

0

Small-scale

0.458

High

1360123

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.458

High

1360128

CALL5
Calmodulin-like protein 5

1

0

High-throughput

0.458

High

1360131

AGO1
Protein argonaute-1

1

0

High-throughput

0.458

High

1360137

MORC2
ATPase MORC2

1

0

High-throughput

0.458

High

340655

STABP
STAM-binding protein

1

1

Small-scale

0.457

High

191727

MAGB2
Melanoma-associated antigen B2

1

2

High-throughput

0.437

High

214878

HNRPR
Heterogeneous nuclear ribonucleoprotein R

1

2

High-throughput

0.437

High

300269

KT33A
Keratin, type I cuticular Ha3-I

1

12

High-throughput

0.437

High

300594

KRT36
Keratin, type I cuticular Ha6

1

9

High-throughput

0.437

High

358758

LDHA
L-lactate dehydrogenase A chain

1

1

High-throughput

0.437

High

380768

HBD
Hemoglobin subunit delta

1

2

High-throughput

0.437

High

402647

ALDOA
Fructose-bisphosphate aldolase A

1

2

High-throughput

0.437

High

449762

H2B1J
Histone H2B type 1-J

1

3

High-throughput

0.437

High

462535

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

2

High-throughput

0.437

High

552330

ADT3
ADP/ATP translocase 3

1

4

High-throughput

0.437

High

634553

LMNB1
Lamin-B1

1

13

High-throughput

0.437

High

660688

IF4B
Eukaryotic translation initiation factor 4B

1

1

High-throughput

0.437

High

693871

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.437

High

729373

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

5

High-throughput

0.437

High

788119

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.437

High

910603

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

1

High-throughput

0.437

High

912982

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

5

High-throughput

0.437

High

999668

HBA
Hemoglobin subunit alpha

1

2

High-throughput

0.437

High

1007495

KRT83
Keratin, type II cuticular Hb3

1

7

High-throughput

0.437

High

1007532

KRT85
Keratin, type II cuticular Hb5

1

7

High-throughput

0.437

High

1010681

DCD
Dermcidin

1

1

High-throughput

0.437

High

1029527

SRSF2
Serine/arginine-rich splicing factor 2

1

1

High-throughput

0.437

High

1047458

K1C17
Keratin, type I cytoskeletal 17

1

12

High-throughput

0.437

High

1064462

DSC1
Desmocollin-1

1

3

High-throughput

0.437

High

1089484

ILF2
Interleukin enhancer-binding factor 2

1

1

High-throughput

0.437

High

1099180

SRSF5
Serine/arginine-rich splicing factor 5

1

2

High-throughput

0.437

High

1127667

KT33B
Keratin, type I cuticular Ha3-II

1

12

High-throughput

0.437

High

1145637

RCN1
Reticulocalbin-1

1

2

High-throughput

0.437

High

1250021

WDR82
WD repeat-containing protein 82

1

9

High-throughput

0.437

High

1280846

K2C1B
Keratin, type II cytoskeletal 1b

1

6

High-throughput

0.437

High

1307285

H2A2B
Histone H2A type 2-B

1

4

High-throughput

0.437

High

1360109

KRT35
Keratin, type I cuticular Ha5

1

12

High-throughput

0.437

High

1360111

H2A1C
Histone H2A type 1-C

1

4

High-throughput

0.437

High

1360112

GCC1
GRIP and coiled-coil domain-containing protein 1

1

3

High-throughput

0.437

High

1360116

H2A1H
Histone H2A type 1-H

1

4

High-throughput

0.437

High

1360125

KRT82
Keratin, type II cuticular Hb2

1

7

High-throughput

0.437

High

1360135

UTP18
U3 small nucleolar RNA-associated protein 18 homolog

1

1

High-throughput

0.437

High

384185

CO1A1
Collagen alpha-1(I) chain

1

0

High-throughput

0.249

Low

443085

PTMA
Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]

1

0

High-throughput

0.249

Low

582107

PGAM2
Phosphoglycerate mutase 2

1

0

High-throughput

0.249

Low

1016357

SERF2
Small EDRK-rich factor 2

1

0

High-throughput

0.249

Low

1098653

SBP1
Methanethiol oxidase

1

0

High-throughput

0.249

Low

1149942

TERF2
Telomeric repeat-binding factor 2

1

0

High-throughput

0.249

Low

1213874

KPLCE
Protein KPLCE

1

0

High-throughput

0.249

Low

1248714

SBSN
Suprabasin

1

0

High-throughput

0.249

Low

1360113

SPF45
Splicing factor 45

1

0

High-throughput

0.249

Low

1360127

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

0

High-throughput

0.249

Low

1360129

CPSF2
Cleavage and polyadenylation specificity factor subunit 2

1

0

High-throughput

0.249

Low

1360130

S30BP
SAP30-binding protein

1

0

High-throughput

0.249

Low

1360134

CHTOP
Chromatin target of PRMT1 protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025