HitPredict

Interactor 1: POC1A (Q8NBT0)
POC1 centriolar protein homolog A (Pix2) (Proteome of centriole protein 1A) (WD repeat-containing protein 51A)
Gene: POC1A

Interactor 2: NELL2 (Q99435)
Protein kinase C-binding protein NELL2 (NEL-like protein 2) (Nel-related protein 2)
Gene: NELL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 407 Hs			1 816
+	Hs
		1253294 POC1B_HUMAN (258-403): 3.81e-30: 122: 12.25		NELL2_HUMAN (1-816): 4.02e-126: 399: 100.00
+	Hs
		126395 POC1A_HUMAN (1-407): 1.25e-118: 352: 100.00		MATN2_HUMAN (486-795): 1.72e-24: 112: 21.02
+	Hs
		980485 FBXW7_HUMAN (131-406): 1.07e-65: 223: 20.79		NOTC2_HUMAN (400-815): 1.5e-25: 116: 19.96
+	Hs
		804311 FBXW7_HUMAN (131-406): 1.07e-65: 223: 20.79		NOTC1_HUMAN (167-649): 2.93e-21: 102: 13.36
+	Hs
		944124 FBXW7_HUMAN (131-406): 1.07e-65: 223: 20.79		JAG1_HUMAN (158-493): 3.44e-10: 66.1: 8.55
+	Hs
		804333 TBL1R_HUMAN (182-405): 2.39e-43: 160: 14.23		NOTC1_HUMAN (167-649): 2.93e-21: 102: 13.36
+	Ce
		537588 SEL10_CAEEL (17-234): 3.65e-17: 85.5: 26.82		LIN12_CAEEL (451-805): 4.65e-29: 127: 20.59
+	Hs
		823032 GBB2_HUMAN (8-131): 4.26e-21: 95.3: 25.98		AGRE5_HUMAN (380-514): 9.87e-20: 96.7: 33.57
+	Hs
		434633 WDR5_HUMAN (259-406): 6.14e-34: 130: 15.44		TSP1_HUMAN (199-741): 5.64e-09: 61.9: 11.05
+	Hs
		921566 GBB2_HUMAN (8-131): 4.26e-21: 95.3: 25.98		FAT1_HUMAN (742-815): 2.57e-11: 70: 14.87
+	Dm
		484996 EBI_DROME (299-401): 1.4e-14: 77.4: 8.55		CRB_DROME (635-814): 2.66e-10: 66.5: 13.72