HitPredict

Interactor 1: SPT5H (O00267)
Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor 160 kDa subunit) (DSIF p160) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (Tat-cotransactivator 1 protein) (Tat-CT1 protein)
Gene: SUPT5H

Interactor 2: SCAFB (Q99590)
Protein SCAF11 (CTD-associated SR protein 11) (Renal carcinoma antigen NY-REN-40) (SC35-interacting protein 1) (SR-related and CTD-associated factor 11) (SRSF2-interacting protein) (Serine/arginine-rich splicing factor 2-interacting protein) (Splicing factor, arginine/serine-rich 2-interacting protein) (Splicing regulatory protein 129) (SRrp129)
Gene: SCAF11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29395067, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1087 Hs			1 1463
+	Hs
		124084 SPT5H_HUMAN (1-1087): 0: 1061: 100.00		SFR19_HUMAN (416-1446): 8.8e-43: 173: 14.16
+	Hs
		123982 SPT5H_HUMAN (1-1087): 0: 1061: 100.00		NIPBL_HUMAN (305-1055): 3.43e-19: 96.9: 9.37
+	Hs
		124057 SPT5H_HUMAN (1-1087): 0: 1061: 100.00		MINT_HUMAN (292-1220): 3.07e-10: 67.6: 8.93
+	Zm
		41124 A0A1D6NSH0_MAIZE (108-1085): 0: 787: 31.68		A0A1D6NFT5_MAIZE (641-1129): 3.46e-17: 90.1: 14.99
+	Hs
		1056910 CBP_HUMAN (747-1035): 5.79e-09: 62.6: 12.81		MDC1_HUMAN (212-1082): 2.36e-25: 117: 9.88
+	Dm
		113976 M9PB30_DROME (623-1074): 3.87e-11: 69.9: 10.12		M9PB30_DROME (169-900): 7.8e-16: 86.2: 10.27
+	Mm
		1351630 PCLO_MOUSE (622-1063): 7.05e-09: 62.6: 11.82		PCLO_MOUSE (937-1421): 2.85e-09: 64.3: 8.57