Protein: SNP23
Synaptosomal-associated protein 23 (SNAP-23) (Vesicle-membrane fusion protein SNAP-23)

Gene: SNP23, SNAP23
Organism: Homo sapiens
Interactions: 200
UniProt ID: O00161

Gene Ontology (top 5):
GO:0002553 - histamine secretion by mast cell
GO:0005484 - SNAP receptor activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

123952

STX11
Syntaxin-11

11

20

Small-scale

0.761

High

124045

STX4
Syntaxin-4

10

20

Small-scale

0.757

High

124048

STX3
Syntaxin-3

10

20

Small-scale

0.754

High

124057

STX1A
Syntaxin-1A

7

20

Small-scale

0.743

High

124070

STX12
Syntaxin-12

6

20

Small-scale

0.733

High

123944

STX7
Syntaxin-7

6

20

High-throughput

0.732

High

123997

STX2
Syntaxin-2

6

20

Small-scale

0.730

High

124056

VAMP3
Vesicle-associated membrane protein 3

6

20

Small-scale

0.724

High

123955

SEGN
Secretagogin

5

1

Small-scale

0.721

High

124019

SNAA
Alpha-soluble NSF attachment protein

4

16

High-throughput

0.710

High

123949

STX6
Syntaxin-6

4

17

Small-scale

0.698

High

124037

VAMP2
Vesicle-associated membrane protein 2

4

20

Small-scale

0.698

High

123958

VAMP5
Vesicle-associated membrane protein 5

3

20

High-throughput

0.669

High

124075

STX19
Syntaxin-19

3

20

High-throughput

0.667

High

124095

VAMP8
Vesicle-associated membrane protein 8

3

20

Small-scale

0.656

High

124015

VAMP7
Vesicle-associated membrane protein 7

3

20

Small-scale

0.646

High

123966

RASK
GTPase KRas

3

11

High-throughput

0.640

High

124078

STXB6
Syntaxin-binding protein 6

2

2

High-throughput

0.628

High

123978

CFTR
Cystic fibrosis transmembrane conductance regulator

2

0

Small-scale

0.592

High

123943

BET1
BET1 homolog

2

13

High-throughput

0.588

High

124030

STX1B
Syntaxin-1B

2

20

Small-scale

0.586

High

123948

CHM2A
Charged multivesicular body protein 2a

2

0

High-throughput

0.585

High

123947

TGON2
Trans-Golgi network integral membrane protein 2

2

1

High-throughput

0.584

High

123975

LAMP1
Lysosome-associated membrane glycoprotein 1

2

5

High-throughput

0.584

High

123990

RAB4A
Ras-related protein Rab-4A

2

6

High-throughput

0.584

High

124013

RAB9A
Ras-related protein Rab-9A

2

7

High-throughput

0.584

High

124033

ARF6
ADP-ribosylation factor 6

2

3

High-throughput

0.584

High

124034

RB11A
Ras-related protein Rab-11A

2

4

High-throughput

0.584

High

124035

RHOB
Rho-related GTP-binding protein RhoB

2

17

High-throughput

0.584

High

123959

SNAPN
SNARE-associated protein Snapin

1

2

Small-scale

0.573

High

124102

SNAB
Beta-soluble NSF attachment protein

1

16

High-throughput

0.573

High

123968

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

124121

STX18
Syntaxin-18

2

3

Small-scale

0.571

High

123935

SNP23
Synaptosomal-associated protein 23

1

8

High-throughput

0.541

High

124116

ABI2
Abl interactor 2

1

7

High-throughput

0.541

High

124118

ABI3
ABI gene family member 3

1

7

High-throughput

0.541

High

123951

VAMP4
Vesicle-associated membrane protein 4

1

20

High-throughput

0.536

High

123962

SNP29
Synaptosomal-associated protein 29

1

8

High-throughput

0.536

High

124006

NSF
Vesicle-fusing ATPase

1

8

High-throughput

0.536

High

124009

CEBPD
CCAAT/enhancer-binding protein delta

1

2

High-throughput

0.536

High

124071

ZDH17
Palmitoyltransferase ZDHHC17

1

2

High-throughput

0.532

High

123998

KINH
Kinesin-1 heavy chain

1

3

Small-scale

0.527

High

124010

FXR2
RNA-binding protein FXR2

1

0

High-throughput

0.518

High

123967

FINC
Fibronectin

1

0

High-throughput

0.513

High

123988

EGLN
Endoglin

1

0

High-throughput

0.513

High

124047

STX5
Syntaxin-5

1

20

Small-scale

0.501

High

124055

ITSN1
Intersectin-1

1

6

Small-scale

0.501

High

124061

STXB5
Syntaxin-binding protein 5

1

5

Small-scale

0.501

High

124113

SNTG1
Gamma-1-syntrophin

1

1

Small-scale

0.501

High

124065

CXB7
Gap junction beta-7 protein

1

3

High-throughput

0.489

High

48426

ESYT2
Extended synaptotagmin-2

1

7

High-throughput

0.479

High

123937

STXB3
Syntaxin-binding protein 3

1

14

Small-scale

0.479

High

123938

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

123941

SCAM1
Secretory carrier-associated membrane protein 1

1

3

Small-scale

0.479

High

123942

SCAM2
Secretory carrier-associated membrane protein 2

1

3

Small-scale

0.479

High

123945

HS12A
Heat shock 70 kDa protein 12A

1

1

High-throughput

0.479

High

123950

EXOC3
Exocyst complex component 3

1

1

Small-scale

0.479

High

123961

DIRA3
GTP-binding protein Di-Ras3

1

3

High-throughput

0.479

High

123964

RASN
GTPase NRas

1

11

High-throughput

0.479

High

123965

RASH
GTPase HRas

1

7

High-throughput

0.479

High

123969

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

123970

LCK
Tyrosine-protein kinase Lck

1

2

High-throughput

0.479

High

123971

LYN
Tyrosine-protein kinase Lyn

1

2

High-throughput

0.479

High

123972

RHOC
Rho-related GTP-binding protein RhoC

1

14

High-throughput

0.479

High

123974

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.479

High

123976

CADH1
Cadherin-1

1

2

High-throughput

0.479

High

123977

LAMP2
Lysosome-associated membrane glycoprotein 2

1

5

High-throughput

0.479

High

123980

RAC2
Ras-related C3 botulinum toxin substrate 2

1

13

High-throughput

0.479

High

123981

EZRI
Ezrin

1

2

High-throughput

0.479

High

123982

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

123984

RHOQ
Rho-related GTP-binding protein RhoQ

1

17

High-throughput

0.479

High

123985

CXA1
Gap junction alpha-1 protein

1

3

High-throughput

0.479

High

123987

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

123989

RAB3B
Ras-related protein Rab-3B

1

5

High-throughput

0.479

High

123991

RAB5A
Ras-related protein Rab-5A

1

7

High-throughput

0.479

High

123995

EPHA2
Ephrin type-A receptor 2

1

6

High-throughput

0.479

High

123996

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

High-throughput

0.479

High

124001

RADI
Radixin

1

1

High-throughput

0.479

High

124002

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

124003

MUC18
Cell surface glycoprotein MUC18

1

2

High-throughput

0.479

High

124005

RECQ1
ATP-dependent DNA helicase Q1

1

1

High-throughput

0.479

High

124008

LMAN1
Protein ERGIC-53

1

1

High-throughput

0.479

High

124011

RAB5C
Ras-related protein Rab-5C

1

7

High-throughput

0.479

High

124012

RAB7A
Ras-related protein Rab-7a

1

7

High-throughput

0.479

High

124014

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

1

High-throughput

0.479

High

124016

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

124020

AFAD
Afadin

1

2

High-throughput

0.479

High

124022

ARL4C
ADP-ribosylation factor-like protein 4C

1

7

High-throughput

0.479

High

124023

STX17
Syntaxin-17

1

4

Small-scale

0.479

High

124024

RAB25
Ras-related protein Rab-25

1

4

High-throughput

0.479

High

124026

RAC3
Ras-related C3 botulinum toxin substrate 3

1

15

High-throughput

0.479

High

124027

CDC42
Cell division control protein 42 homolog

1

17

High-throughput

0.479

High

124028

RAB2A
Ras-related protein Rab-2A

1

6

High-throughput

0.479

High

124031

RHOA
Transforming protein RhoA

1

16

High-throughput

0.479

High

124032

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.479

High

124036

RAC1
Ras-related C3 botulinum toxin substrate 1

1

15

High-throughput

0.479

High

124040

CXAR
Coxsackievirus and adenovirus receptor

1

2

High-throughput

0.479

High

124041

RHOG
Rho-related GTP-binding protein RhoG

1

13

High-throughput

0.479

High

124044

CAV1
Caveolin-1

1

1

High-throughput

0.479

High

124046

TP4A2
Protein tyrosine phosphatase type IVA 2

1

1

Small-scale

0.479

High

124049

SQSTM
Sequestosome-1

1

1

High-throughput

0.479

High

124052

RAB35
Ras-related protein Rab-35

1

4

High-throughput

0.479

High

124053

KS6A2
Ribosomal protein S6 kinase alpha-2

1

1

High-throughput

0.479

High

124054

RHOH
Rho-related GTP-binding protein RhoH

1

18

High-throughput

0.479

High

124058

OCLN
Occludin

1

1

High-throughput

0.479

High

124062

RNF43
E3 ubiquitin-protein ligase RNF43

1

1

High-throughput

0.479

High

124063

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

124067

MOB2
MOB kinase activator 2

1

1

High-throughput

0.479

High

124068

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

124074

CXD3
Gap junction delta-3 protein

1

3

High-throughput

0.479

High

124076

ARL14
ADP-ribosylation factor-like protein 14

1

4

High-throughput

0.479

High

124080

PARD3
Partitioning defective 3 homolog

1

1

High-throughput

0.479

High

124082

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.479

High

124083

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

124086

CLUA1
Clusterin-associated protein 1

1

1

High-throughput

0.479

High

124090

RHOV
Rho-related GTP-binding protein RhoV

1

18

High-throughput

0.479

High

124093

PANX1
Pannexin-1

1

1

High-throughput

0.479

High

124103

DNJC5
DnaJ homolog subfamily C member 5

1

3

High-throughput

0.479

High

124104

RHOJ
Rho-related GTP-binding protein RhoJ

1

17

High-throughput

0.479

High

124105

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.479

High

124108

RHOF
Rho-related GTP-binding protein RhoF

1

19

High-throughput

0.479

High

124110

E41LA
Band 4.1-like protein 4A

1

1

High-throughput

0.479

High

124115

ARL15
ADP-ribosylation factor-like protein 15

1

6

High-throughput

0.479

High

124123

DNJ5B
DnaJ homolog subfamily C member 5B

1

3

High-throughput

0.479

High

124124

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

124125

SEPT9
Septin-9

1

3

Small-scale

0.479

High

124127

ALK
ALK tyrosine kinase receptor

1

8

High-throughput

0.479

High

124128

LAMP3
Lysosome-associated membrane glycoprotein 3

1

5

High-throughput

0.479

High

124131

ARL5A
ADP-ribosylation factor-like protein 5A

1

4

High-throughput

0.479

High

124004

MATR3
Matrin-3

1

1

High-throughput

0.464

High

123936

LEG9
Galectin-9

1

0

High-throughput

0.458

High

123940

CLD4
Claudin-4

1

0

Small-scale

0.458

High

123946

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

Small-scale

0.458

High

123953

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

123954

FLOT1
Flotillin-1

1

0

High-throughput

0.458

High

123956

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.458

High

123963

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

123973

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

123979

AMPN
Aminopeptidase N

1

0

High-throughput

0.458

High

123986

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

0

High-throughput

0.458

High

123992

CBL
E3 ubiquitin-protein ligase CBL

1

0

High-throughput

0.458

High

123993

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

123994

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

123999

CTNA1
Catenin alpha-1

1

0

Small-scale

0.458

High

124000

CTNB1
Catenin beta-1

1

0

High-throughput

0.458

High

124007

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

124017

ATX3
Ataxin-3

1

0

High-throughput

0.458

High

124018

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

0

High-throughput

0.458

High

124021

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

124029

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.458

High

124038

DYLT1
Dynein light chain Tctex-type 1

1

0

High-throughput

0.458

High

124042

VIGLN
Vigilin

1

0

High-throughput

0.458

High

124050

CUL3
Cullin-3

1

0

High-throughput

0.458

High

124051

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

0

High-throughput

0.458

High

124059

MIDN
Midnolin

1

0

High-throughput

0.458

High

124073

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.458

High

124084

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.458

High

124085

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.458

High

124087

CHM4C
Charged multivesicular body protein 4c

1

0

High-throughput

0.458

High

124099

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

124100

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

0

Small-scale

0.458

High

124101

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

124112

DUS22
Dual specificity protein phosphatase 22

1

0

High-throughput

0.458

High

124117

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

124119

ANFY1
Rabankyrin-5

1

0

High-throughput

0.458

High

124122

HDAC6
Protein deacetylase HDAC6

1

0

High-throughput

0.458

High

124043

DYST
Dystonin

1

3

Small-scale

0.457

High

124066

WASH2
WAS protein family homolog 2

1

1

High-throughput

0.457

High

124130

STB5L
Syntaxin-binding protein 5-like

1

5

Small-scale

0.457

High

124079

SCAM5
Secretory carrier-associated membrane protein 5

1

3

Small-scale

0.445

High

124098

ZDHC5
Palmitoyltransferase ZDHHC5

1

2

High-throughput

0.445

High

124114

DDX28
Probable ATP-dependent RNA helicase DDX28

1

1

High-throughput

0.445

High

71413

P20L1
PHD finger protein 20-like protein 1

1

0

Small-scale

0.438

High

124039

GBG3

1

0

Small-scale

0.438

High

124129

TBC30
TBC1 domain family member 30

1

0

Small-scale

0.438

High

123957

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.437

High

124072

CEP97
Centrosomal protein of 97 kDa

1

1

Small-scale

0.437

High

124091

HS12B
Heat shock 70 kDa protein 12B

1

1

High-throughput

0.437

High

124092

FMNL2
Formin-like protein 2

1

1

High-throughput

0.437

High

124120

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.437

High

123960

NPT2B
Sodium-dependent phosphate transport protein 2B

1

0

High-throughput

0.426

High

123983

ANFB
Natriuretic peptides B

1

0

High-throughput

0.426

High

124025

CD81
CD81 antigen

1

0

High-throughput

0.426

High

124060

CL12A
C-type lectin domain family 12 member A

1

0

High-throughput

0.426

High

124064

MFS12
Major facilitator superfamily domain-containing protein 12

1

0

High-throughput

0.426

High

124081

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

1

0

High-throughput

0.426

High

124088

DTBP1
Dysbindin

1

0

High-throughput

0.426

High

124094

ZBT18
Zinc finger and BTB domain-containing protein 18

1

0

High-throughput

0.426

High

124096

S46A2
Solute carrier family 46 member 2

1

0

High-throughput

0.426

High

124097

S19A3
Thiamine transporter 2

1

0

High-throughput

0.426

High

124107

SH24A
SH2 domain-containing protein 4A

1

0

High-throughput

0.426

High

124109

ANKH
Mineralization regulator ANKH

1

0

High-throughput

0.426

High

124111

SO1B3
Solute carrier organic anion transporter family member 1B3

1

0

High-throughput

0.426

High

124126

TLK1
Serine/threonine-protein kinase tousled-like 1

1

0

Small-scale

0.324

High

124089

CERS2
Ceramide synthase 2

1

0

High-throughput

0.279

Low

123939

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

124069

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

124077

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.249

Low

124106

HAUS4
HAUS augmin-like complex subunit 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025