HitPredict

Interactor 1: RN149 (Q8NC42)
E3 ubiquitin-protein ligase RNF149 (EC 2.3.2.27) (DNA polymerase-transactivated protein 2) (RING finger protein 149) (RING-type E3 ubiquitin transferase RNF149)
Gene: RNF149

Interactor 2: RN133 (Q8WVZ7)
E3 ubiquitin-protein ligase RNF133 (EC 2.3.2.27) (RING finger protein 133) (RING-type E3 ubiquitin transferase RNF133)
Gene: RNF133

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PA~PA, zf-RING_2~zf-RING_2
Common GO terms GO:0005737 - cytoplasm
GO:0005770 - late endosome
GO:0005783 - endoplasmic reticulum
GO:0005794 - Golgi apparatus
GO:0006511 - ubiquitin-dependent protein catabolic process
and 2 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 400
Hs

1 376
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024