HitPredict

Interactor 1: TAF4 (O00268)
Transcription initiation factor TFIID subunit 4 (RNA polymerase II TBP-associated factor subunit C) (TBP-associated factor 4) (Transcription initiation factor TFIID 130 kDa subunit) (TAF(II)130) (TAFII-130) (TAFII130) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135)
Gene: TAF4

Interactor 2: ATF7 (P17544)
Cyclic AMP-dependent transcription factor ATF-7 (cAMP-dependent transcription factor ATF-7) (Activating transcription factor 7) (Transcription factor ATF-A)
Gene: ATF7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	15735663
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1085 Hs			1 483
+	Hs
		124154 TAF4_HUMAN (1-1085): 1.72e-83: 296: 100.00		JUN_HUMAN (94-409): 4.25e-45: 162: 15.89
+	Hs
		124161 TAF4_HUMAN (1-1085): 1.72e-83: 296: 100.00		CREB1_HUMAN (89-383): 4.8e-27: 112: 15.25
+	Hs
		124144 TAF4_HUMAN (1-1085): 1.72e-83: 296: 100.00		CREB3_HUMAN (209-437): 5.57e-24: 105: 17.92
+	Hs
		402260 KMT2C_HUMAN (4-867): 7.32e-31: 134: 12.05		JUN_HUMAN (94-409): 4.25e-45: 162: 15.89
+	Hs
		402007 MDC1_HUMAN (4-966): 1.09e-29: 130: 11.32		JUN_HUMAN (94-409): 4.25e-45: 162: 15.89
+	Hs
		401362 MUC1_HUMAN (88-827): 4.92e-29: 128: 12.96		JUN_HUMAN (94-409): 4.25e-45: 162: 15.89
+	Hs
		402174 SRCAP_HUMAN (75-749): 9.61e-10: 65.4: 17.69		JUN_HUMAN (94-409): 4.25e-45: 162: 15.89