Interactor 1: DFFA (O00273)
DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD)
Gene: DFFA

Interactor 2: CASP3 (P42574)
Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12]
Gene: CASP3

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.60 0.602

The method score is based on:

Property Details
Experiments 18723680, 11406587
Identification Methods enzymatic study, protease assay
Interaction Type direct interaction, protein cleavage

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 331
Hs

1 277
+ Mm
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024