Protein: MLF2
Myeloid leukemia factor 2 (Myelodysplasia-myeloid leukemia factor 2)

Gene: MLF2
Organism: Homo sapiens
Interactions: 203
UniProt ID: Q15773

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006355 - regulation of DNA-templated transcription
GO:0016020 - membrane
GO:0098978 - glutamatergic synapse

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

274594

DNJB6
DnaJ homolog subfamily B member 6

4

13

High-throughput

0.703

High

1153610

HSPB8
Heat shock protein beta-8

3

3

High-throughput

0.669

High

347721

BAG3
BAG family molecular chaperone regulator 3

2

6

High-throughput

0.635

High

1153615

CHIP
E3 ubiquitin-protein ligase CHIP

2

2

High-throughput

0.635

High

1153581

DNJC7
DnaJ homolog subfamily C member 7

3

6

High-throughput

0.633

High

348515

AIFM1
Apoptosis-inducing factor 1, mitochondrial

3

0

High-throughput

0.622

High

347049

BAG2
BAG family molecular chaperone regulator 2

3

2

High-throughput

0.616

High

679167

DNJB1
DnaJ homolog subfamily B member 1

2

7

High-throughput

0.611

High

731332

STIP1
Stress-induced-phosphoprotein 1

2

1

High-throughput

0.611

High

1153623

CIA2B
Cytosolic iron-sulfur assembly component 2B

2

1

High-throughput

0.601

High

537220

HSP7C
Heat shock cognate 71 kDa protein

2

5

High-throughput

0.588

High

1153612

BAG5
BAG family molecular chaperone regulator 5

2

6

High-throughput

0.584

High

1153579

MMS19
MMS19 nucleotide excision repair protein homolog

2

0

High-throughput

0.576

High

400891

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

2

High-throughput

0.571

High

436675

KPCB
Protein kinase C beta type

2

1

High-throughput

0.571

High

413908

P53
Cellular tumor antigen p53

1

2

Small-scale

0.561

High

1153526

EZH2
Histone-lysine N-methyltransferase EZH2

2

0

High-throughput

0.559

High

1153608

DNJB4
DnaJ homolog subfamily B member 4

2

7

High-throughput

0.558

High

1153583

BAG1
BAG family molecular chaperone regulator 1

1

1

High-throughput

0.554

High

399976

CATA
Catalase

2

0

High-throughput

0.547

High

1153551

TBA1A
Tubulin alpha-1A chain

2

0

High-throughput

0.547

High

1153572

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

Small-scale

0.537

High

336675

BAG4
BAG family molecular chaperone regulator 4

1

6

High-throughput

0.536

High

600820

HSP76
Heat shock 70 kDa protein 6

1

5

High-throughput

0.536

High

927318

ATX1
Ataxin-1

1

2

High-throughput

0.536

High

1103866

ZN211
Zinc finger protein 211

1

1

High-throughput

0.536

High

1115678

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

1

High-throughput

0.536

High

1153575

HDA11
Histone deacetylase 11

1

2

High-throughput

0.536

High

1153582

NPAS1
Neuronal PAS domain-containing protein 1

1

4

High-throughput

0.536

High

1153602

NRBP2
Nuclear receptor-binding protein 2

1

4

High-throughput

0.536

High

566991

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.518

High

303133

RGS20
Regulator of G-protein signaling 20

1

1

High-throughput

0.515

High

761410

HS71L
Heat shock 70 kDa protein 1-like

1

5

High-throughput

0.515

High

872366

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.513

High

905574

IRAK1
Interleukin-1 receptor-associated kinase 1

1

0

High-throughput

0.513

High

930707

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

0

High-throughput

0.513

High

1153529

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.513

High

1153557

MTA70
N(6)-adenosine-methyltransferase catalytic subunit METTL3

1

0

High-throughput

0.513

High

1153560

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.513

High

1153603

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.513

High

1153618

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

0

High-throughput

0.513

High

1153624

LMBL1
Lethal(3)malignant brain tumor-like protein 1

1

0

High-throughput

0.513

High

1153527

HSPB2
Heat shock protein beta-2

1

3

High-throughput

0.508

High

728256

AKT1
RAC-alpha serine/threonine-protein kinase

1

2

Small-scale

0.501

High

302840

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

0

High-throughput

0.493

High

701830

ABCD3
ATP-binding cassette sub-family D member 3

1

0

High-throughput

0.493

High

1142984

PMVK
Phosphomevalonate kinase

1

0

High-throughput

0.493

High

302061

SEGN
Secretagogin

1

0

Small-scale

0.480

High

163642

GNB5
Guanine nucleotide-binding protein subunit beta-5

1

7

High-throughput

0.479

High

207963

TET3
Methylcytosine dioxygenase TET3

1

1

High-throughput

0.479

High

210956

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

3

High-throughput

0.479

High

292129

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

3

High-throughput

0.479

High

298912

DNJB5
DnaJ homolog subfamily B member 5

1

7

High-throughput

0.479

High

326148

REC8
Meiotic recombination protein REC8 homolog

1

1

High-throughput

0.479

High

342887

HERC2
E3 ubiquitin-protein ligase HERC2

1

3

High-throughput

0.479

High

349095

LATS1
Serine/threonine-protein kinase LATS1

1

2

High-throughput

0.479

High

364139

MOS
Proto-oncogene serine/threonine-protein kinase mos

1

1

High-throughput

0.479

High

410866

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

1

High-throughput

0.479

High

415594

HSPB1
Heat shock protein beta-1

1

3

Small-scale

0.479

High

425524

ISG15
Ubiquitin-like protein ISG15

1

2

Small-scale

0.479

High

459296

CATL1
Procathepsin L

1

1

High-throughput

0.479

High

466271

RHOC
Rho-related GTP-binding protein RhoC

1

2

High-throughput

0.479

High

487356

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.479

High

520083

ANDR
Androgen receptor

1

2

High-throughput

0.479

High

618460

GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha

1

5

High-throughput

0.479

High

622814

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

1

High-throughput

0.479

High

679343

DNJB2
DnaJ homolog subfamily B member 2

1

12

High-throughput

0.479

High

755933

MCM5
DNA replication licensing factor MCM5

1

3

High-throughput

0.479

High

756214

MCM7
DNA replication licensing factor MCM7

1

3

High-throughput

0.479

High

799627

GNAL
Guanine nucleotide-binding protein G(olf) subunit alpha

1

6

High-throughput

0.479

High

846749

GRK6
G protein-coupled receptor kinase 6

1

5

High-throughput

0.479

High

930899

HSP72
Heat shock-related 70 kDa protein 2

1

5

High-throughput

0.479

High

946115

MLF1
Myeloid leukemia factor 1

1

1

High-throughput

0.479

High

947351

NAL12
NACHT, LRR and PYD domains-containing protein 12

1

2

High-throughput

0.479

High

955206

CDC42
Cell division control protein 42 homolog

1

2

High-throughput

0.479

High

962083

RHOA
Transforming protein RhoA

1

2

High-throughput

0.479

High

976742

ERF1
Eukaryotic peptide chain release factor subunit 1

1

1

High-throughput

0.479

High

983493

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

7

High-throughput

0.479

High

1097993

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

1

High-throughput

0.479

High

1101821

SKP2
S-phase kinase-associated protein 2

1

1

High-throughput

0.479

High

1113196

CUL3
Cullin-3

1

1

High-throughput

0.479

High

1115209

CUL4B
Cullin-4B

1

1

Small-scale

0.479

High

1121230

TRI14
Tripartite motif-containing protein 14

1

1

High-throughput

0.479

High

1139715

SETB1
Histone-lysine N-methyltransferase SETDB1

1

2

High-throughput

0.479

High

1151704

RHOH
Rho-related GTP-binding protein RhoH

1

3

High-throughput

0.479

High

1153525

STK11
Serine/threonine-protein kinase STK11

1

2

High-throughput

0.479

High

1153532

KLH38
Kelch-like protein 38

1

1

High-throughput

0.479

High

1153538

DCAF8
DDB1- and CUL4-associated factor 8

1

1

Small-scale

0.479

High

1153539

Q5ULA9
Monoamine oxidase A

1

1

High-throughput

0.479

High

1153550

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

1153554

GET4
Golgi to ER traffic protein 4 homolog

1

1

High-throughput

0.479

High

1153561

SIR6
NAD-dependent protein deacylase sirtuin-6

1

1

High-throughput

0.479

High

1153566

DNJA4
DnaJ homolog subfamily A member 4

1

6

High-throughput

0.479

High

1153568

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

1153569

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

1

High-throughput

0.479

High

1153574

GASP2
G-protein coupled receptor-associated sorting protein 2

1

1

High-throughput

0.479

High

1153584

AASD1
Alanyl-tRNA editing protein Aarsd1

1

1

High-throughput

0.479

High

1153592

TBB1
Tubulin beta-1 chain

1

2

High-throughput

0.479

High

1153604

HYPK
Huntingtin-interacting protein K

1

1

Small-scale

0.479

High

1153605

TLR7
Toll-like receptor 7

1

1

High-throughput

0.479

High

1153606

E2AK4
eIF-2-alpha kinase GCN2

1

1

High-throughput

0.479

High

1153607

HDAC6
Protein deacetylase HDAC6

1

1

High-throughput

0.479

High

1153619

NOD1
Nucleotide-binding oligomerization domain-containing protein 1

1

2

High-throughput

0.479

High

133748

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.458

High

138129

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

High-throughput

0.458

High

172852

XPO1
Exportin-1

1

0

High-throughput

0.458

High

277361

TP4A3
Protein tyrosine phosphatase type IVA 3

1

0

High-throughput

0.458

High

293745

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

321549

PRP6
Pre-mRNA-processing factor 6

1

0

High-throughput

0.458

High

408072

TBB4A
Tubulin beta-4A chain

1

0

High-throughput

0.458

High

461514

HS90A
Heat shock protein HSP 90-alpha

1

0

Small-scale

0.458

High

508029

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.458

High

600420

ZKSC1
Zinc finger protein with KRAB and SCAN domains 1

1

0

High-throughput

0.458

High

664753

CCND1
G1/S-specific cyclin-D1

1

0

High-throughput

0.458

High

830807

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

851572

GATA4
Transcription factor GATA-4

1

0

High-throughput

0.458

High

879137

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

907444

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

0

Small-scale

0.458

High

937763

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

983821

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

Small-scale

0.458

High

1033688

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

1045330

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1136641

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

0

High-throughput

0.458

High

1137311

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

1153528

DDB1
DNA damage-binding protein 1

1

0

Small-scale

0.458

High

1153555

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1153556

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

1153558

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.458

High

1153567

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

1

0

High-throughput

0.458

High

1153570

IRF7
Interferon regulatory factor 7

1

0

Small-scale

0.458

High

1153571

KAT5
Histone acetyltransferase KAT5

1

0

High-throughput

0.458

High

1153577

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1153580

TBX5
T-box transcription factor TBX5

1

0

High-throughput

0.458

High

1153586

TSSK6
Testis-specific serine/threonine-protein kinase 6

1

0

High-throughput

0.458

High

1153589

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

0

High-throughput

0.458

High

1153590

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

1153591

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

1153595

WDR55
WD repeat-containing protein 55

1

0

High-throughput

0.458

High

1153596

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1153597

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.458

High

1153611

FBW1B
F-box/WD repeat-containing protein 11

1

0

High-throughput

0.458

High

1153616

FAF1
FAS-associated factor 1

1

0

High-throughput

0.458

High

1153617

DYN3
Dynamin-3

1

0

High-throughput

0.458

High

1153620

SYFA
Phenylalanine--tRNA ligase alpha subunit

1

0

High-throughput

0.458

High

943947

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

3

High-throughput

0.445

High

1153541

ZN772
Zinc finger protein 772

1

2

High-throughput

0.445

High

75609

B3KTT5
cDNA FLJ38698 fis, clone KIDNE2002015, highly similar to HEAT SHOCK 70 kDa PROTEIN 1

1

6

High-throughput

0.437

High

124358

HAX1
HCLS1-associated protein X-1

1

1

High-throughput

0.437

High

160511

IRS4
Insulin receptor substrate 4

1

1

High-throughput

0.437

High

680708

CATS
Cathepsin S

1

1

High-throughput

0.437

High

721450

GNA15
Guanine nucleotide-binding protein subunit alpha-15

1

6

High-throughput

0.437

High

723663

CALCR
Calcitonin receptor

1

1

High-throughput

0.437

High

846009

CACP
Carnitine O-acetyltransferase

1

1

High-throughput

0.437

High

910068

RND2
Rho-related GTP-binding protein RhoN

1

2

High-throughput

0.437

High

1122902

SIM2
Single-minded homolog 2

1

4

High-throughput

0.437

High

1124962

RCN2
Reticulocalbin-2

1

4

High-throughput

0.437

High

1153530

Q1MSW8
Cellular tumor antigen p53

1

2

High-throughput

0.437

High

1153533

EIPR1
EARP and GARP complex-interacting protein 1

1

1

High-throughput

0.437

High

1153534

Q59FM5
Guanine nucleotide-binding protein subunit alpha

1

5

High-throughput

0.437

High

1153535

Q59G26
Guanine nucleotide-binding protein, beta-3 subunit variant

1

7

High-throughput

0.437

High

1153536

Q59H13
exodeoxyribonuclease III

1

1

High-throughput

0.437

High

1153537

Q5T7U4
General transcription factor IIIC subunit 5

1

1

High-throughput

0.437

High

1153542

Q6FHF7
Geranylgeranyl transferase type-2 subunit alpha

1

1

High-throughput

0.437

High

1153543

Q6FHM2
Epididymis secretory sperm binding protein

1

7

High-throughput

0.437

High

1153544

Q6IAW5
Calumenin

1

4

High-throughput

0.437

High

1153552

Q76GR4
Ligase I, DNA, ATP-dependent

1

1

High-throughput

0.437

High

1153564

HUS1B
Checkpoint protein HUS1B

1

1

High-throughput

0.437

High

1153573

Q96BE0
Heat shock cognate 71 kDa protein

1

8

High-throughput

0.437

High

1153585

Q9BWF4
DNA helicase

1

6

High-throughput

0.437

High

1153588

RHBT2
Rho-related BTB domain-containing protein 2

1

2

High-throughput

0.437

High

1153593

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

2

High-throughput

0.437

High

1153594

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

1

High-throughput

0.437

High

1153600

DBLOH
Diablo IAP-binding mitochondrial protein

1

1

High-throughput

0.437

High

1033989

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

0

High-throughput

0.426

High

1153562

ZN614
Zinc finger protein 614

1

0

High-throughput

0.426

High

1153598

ZFP14
Zinc finger protein 14 homolog

1

0

High-throughput

0.426

High

1153609

ZN180
Zinc finger protein 180

1

0

High-throughput

0.426

High

1153621

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.426

High

1153546

SCMC2
Mitochondrial adenyl nucleotide antiporter SLC25A25

1

3

High-throughput

0.407

High

1153601

ARHG4
Rho guanine nucleotide exchange factor 4

2

0

High-throughput

0.298

High

62366

A4FVC0
Protein argonaute-1

1

0

High-throughput

0.249

Low

69436

A8K2M0
26S proteasome regulatory subunit 6B

1

0

High-throughput

0.249

Low

651811

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

0

High-throughput

0.249

Low

1053333

Q05C05
HCFC1 protein

1

0

High-throughput

0.249

Low

1153531

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1153540

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low

1153545

Q6IBR0
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.249

Low

1153547

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1153548

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.249

Low

1153549

Q6ZNJ8
FLJ00321 protein

1

0

High-throughput

0.249

Low

1153553

CYFP1
Cytoplasmic FMR1-interacting protein 1

1

0

High-throughput

0.249

Low

1153559

Q8IWP3
Kappa-type opioid receptor

1

0

High-throughput

0.249

Low

1153565

Q8TDZ3
MYHbeta

1

0

High-throughput

0.249

Low

1153576

RNF31
E3 ubiquitin-protein ligase RNF31

1

0

High-throughput

0.249

Low

1153578

Q96PK0
COPG2

1

0

High-throughput

0.249

Low

1153599

ANLN
Anillin

1

0

High-throughput

0.249

Low

1153613

ANR50
Ankyrin repeat domain-containing protein 50

1

0

High-throughput

0.249

Low

1153614

Q9UMP2
DNA mismatch repair protein

1

0

High-throughput

0.249

Low

1153622

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

1153625

COPG1
Coatomer subunit gamma-1

1

0

High-throughput

0.249

Low

321247

ERLN2
Erlin-2

1

0

Small-scale

0.232

Low

1153563

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low

1153587

S17A9
Voltage-gated purine nucleotide uniporter SLC17A9

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025