Interactor 1: PK3C3 (Q8NEB9)
Phosphatidylinositol 3-kinase catalytic subunit type 3 (PI3-kinase type 3) (PI3K type 3) (PtdIns-3-kinase type 3) (EC 2.7.1.137) (Phosphatidylinositol 3-kinase p100 subunit) (Phosphoinositide-3-kinase class 3) (hVps34)
Gene: PIK3C3

Interactor 2: RUBIC (Q92622)
Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (Rubicon) (Beclin-1 associated RUN domain containing protein) (Baron)
Gene: RUBCN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.756

The method score is based on:

Property Details
Experiments 35271311, 20562859, 25533187, 30686098, 33961781, 19270696, 24980960, 22423967, 21062745
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, tandem affinity purification, pull down
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005770 - late endosome
GO:0005829 - cytosol
GO:0006914 - autophagy
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 887
Hs

1 972
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024