HitPredict

Interactor 1: DOCK8 (Q8NF50)
Dedicator of cytokinesis protein 8
Gene: DOCK8

Interactor 2: DOCK7 (Q96N67)
Dedicator of cytokinesis protein 7
Gene: DOCK7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.965

The method score is based on:

Property Details
Experiments 29467281, 35271311, 28514442, 32203420, 33961781, 24255178, unassigned2213
Identification Methods proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DHR-2_Lobe_A~DHR-2_Lobe_A, DHR-2_Lobe_A~DHR-2_Lobe_B, DHR-2_Lobe_B~DHR-2_Lobe_C, DHR-2_Lobe_C~DHR-2_Lobe_C, DOCK-C2~DOCK-C2
Common GO terms GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0007264 - small GTPase-mediated signal transduction
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 2099
Hs

1 2140
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Last updated: 15 Jul 2024