Protein: SP110
Sp110 nuclear body protein (Interferon-induced protein 41/75) (Speckled 110 kDa) (Transcriptional coactivator Sp110)

Gene: SP110
Organism: Homo sapiens
Interactions: 122
UniProt ID: Q9HB58

Gene Ontology (top 5):
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

161459

MYPT1
Protein phosphatase 1 regulatory subunit 12A

2

11

High-throughput

0.611

High

586993

CSK22
Casein kinase II subunit alpha'

2

8

High-throughput

0.611

High

1289444

SIR1
NAD-dependent protein deacetylase sirtuin-1

2

12

High-throughput

0.611

High

1319059

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

2

16

High-throughput

0.611

High

1335102

CHIP
E3 ubiquitin-protein ligase CHIP

2

2

High-throughput

0.611

High

1284936

ARK2N
Protein ARK2N

2

0

High-throughput

0.585

High

182430

ZSC9
Zinc finger and SCAN domain-containing protein 9

1

20

High-throughput

0.541

High

1045145

RUNX3
Runt-related transcription factor 3

1

1

High-throughput

0.541

High

1335100

NP1L2
Nucleosome assembly protein 1-like 2

1

9

High-throughput

0.541

High

176282

PPM1G
Protein phosphatase 1G

1

2

High-throughput

0.536

High

238742

IMA7
Importin subunit alpha-7

1

15

High-throughput

0.536

High

528032

RINI
Ribonuclease inhibitor

1

5

High-throughput

0.536

High

906143

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

13

High-throughput

0.536

High

931877

CSK2B
Casein kinase II subunit beta

1

2

High-throughput

0.536

High

1059569

KIF22
Kinesin-like protein KIF22

1

11

High-throughput

0.536

High

1060930

IMB1
Importin subunit beta-1

1

14

High-throughput

0.536

High

1086113

ZSC26
Zinc finger and SCAN domain-containing protein 26

1

20

High-throughput

0.536

High

1291513

THOC1
THO complex subunit 1

1

1

High-throughput

0.536

High

584081

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

0

High-throughput

0.518

High

271790

PRDM1
PR domain zinc finger protein 1

1

20

Small-scale

0.515

High

319059

CEP43
Centrosomal protein 43

1

0

High-throughput

0.513

High

378775

KITH
Thymidine kinase, cytosolic

1

2

High-throughput

0.508

High

589248

ANXA7
Annexin A7

1

6

High-throughput

0.508

High

758340

CDN1A
Cyclin-dependent kinase inhibitor 1

1

2

High-throughput

0.508

High

1077344

T22D1
TSC22 domain family protein 1

1

17

High-throughput

0.508

High

1084905

SMN
Survival motor neuron protein

1

2

High-throughput

0.508

High

1335092

OSGEP
tRNA N6-adenosine threonylcarbamoyltransferase

1

1

High-throughput

0.508

High

160786

AURKA
Aurora kinase A

1

8

High-throughput

0.479

High

196351

PJA2
E3 ubiquitin-protein ligase Praja-2

1

2

High-throughput

0.479

High

244960

BRD4
Bromodomain-containing protein 4

1

20

High-throughput

0.479

High

271421

NPM3
Nucleoplasmin-3

1

9

High-throughput

0.479

High

309747

KAT7
Histone acetyltransferase KAT7

1

7

High-throughput

0.479

High

387543

P53
Cellular tumor antigen p53

1

13

High-throughput

0.479

High

418683

NPM
Nucleophosmin

1

9

High-throughput

0.479

High

422574

CENPB
Major centromere autoantigen B

1

4

High-throughput

0.479

High

483609

SETLP
Protein SETSIP

1

8

High-throughput

0.479

High

501088

IRF1
Interferon regulatory factor 1

1

6

Small-scale

0.479

High

548752

VAV
Proto-oncogene vav

1

4

High-throughput

0.479

High

583804

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

1

High-throughput

0.479

High

600233

TAF1
Transcription initiation factor TFIID subunit 1

1

20

High-throughput

0.479

High

617668

CRCM
Colorectal mutant cancer protein

1

8

High-throughput

0.479

High

800531

CBX5
Chromobox protein homolog 5

1

20

High-throughput

0.479

High

831701

CEBPA
CCAAT/enhancer-binding protein alpha

1

13

Small-scale

0.479

High

846234

RT29
Small ribosomal subunit protein mS29

1

2

High-throughput

0.479

High

917954

H4
Histone H4

1

13

High-throughput

0.479

High

949890

CBX1
Chromobox protein homolog 1

1

20

High-throughput

0.479

High

963903

SET
Protein SET

1

8

High-throughput

0.479

High

974519

ENL
Protein ENL

1

20

High-throughput

0.479

High

976514

ERCC6
DNA excision repair protein ERCC-6

1

18

High-throughput

0.479

High

1019133

TP53B
TP53-binding protein 1

1

14

High-throughput

0.479

High

1027272

CBX3
Chromobox protein homolog 3

1

20

High-throughput

0.479

High

1068927

PCM1
Pericentriolar material 1 protein

1

1

High-throughput

0.479

High

1069273

2A5A
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform

1

2

High-throughput

0.479

High

1133766

BEND3
BEN domain-containing protein 3

1

3

High-throughput

0.479

High

1186268

PHF5A
PHD finger-like domain-containing protein 5A

1

1

High-throughput

0.479

High

1223943

RCOR2
REST corepressor 2

1

20

High-throughput

0.479

High

1239418

MLKL
Mixed lineage kinase domain-like protein

1

7

High-throughput

0.479

High

1239507

ANR52
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C

1

10

High-throughput

0.479

High

1245341

KNL1
Kinetochore scaffold 1

1

1

High-throughput

0.479

High

1251175

G45IP
Large ribosomal subunit protein mL64

1

2

High-throughput

0.479

High

1269658

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1273890

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

10

Small-scale

0.479

High

1290634

PTCD3
Small ribosomal subunit protein mS39

1

1

High-throughput

0.479

High

1293732

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

1

High-throughput

0.479

High

1295111

EAF1
ELL-associated factor 1

1

1

High-throughput

0.479

High

1295347

DCAF5
DDB1- and CUL4-associated factor 5

1

20

High-throughput

0.479

High

1302965

SETB2
Histone-lysine N-methyltransferase SETDB2

1

11

High-throughput

0.479

High

1309603

SENP7
Sentrin-specific protease 7

1

6

High-throughput

0.479

High

1314079

GNL3
Guanine nucleotide-binding protein-like 3

1

9

High-throughput

0.479

High

1317558

BACH2
Transcription regulator protein BACH2

1

20

High-throughput

0.479

High

1317581

SETD2
Histone-lysine N-methyltransferase SETD2

1

19

High-throughput

0.479

High

1317893

GTPB4
GTP-binding protein 4

1

6

High-throughput

0.479

High

1327310

LSG1
Large subunit GTPase 1 homolog

1

9

High-throughput

0.479

High

1327653

BRD8
Bromodomain-containing protein 8

1

17

High-throughput

0.479

High

1334995

CLSPN
Claspin

1

6

High-throughput

0.479

High

1335089

ELL3
RNA polymerase II elongation factor ELL3

1

1

High-throughput

0.479

High

1335093

RAD18
E3 ubiquitin-protein ligase RAD18

1

4

High-throughput

0.479

High

1335095

AFF4
AF4/FMR2 family member 4

1

14

High-throughput

0.479

High

1335097

CDC23
Cell division cycle protein 23 homolog

1

15

High-throughput

0.479

High

1335099

BRPF3
Bromodomain and PHD finger-containing protein 3

1

20

High-throughput

0.479

High

1335101

APC10
Anaphase-promoting complex subunit 10

1

8

High-throughput

0.479

High

1335104

DCAF1
DDB1- and CUL4-associated factor 1

1

19

High-throughput

0.479

High

1335105

OAS3
2'-5'-oligoadenylate synthase 3

1

2

High-throughput

0.479

High

363653

TTHY
Transthyretin

1

1

High-throughput

0.464

High

930123

SPT4H
Transcription elongation factor SPT4

1

0

High-throughput

0.458

High

942075

RPP38
Ribonuclease P protein subunit p38

1

0

High-throughput

0.458

High

1147531

UTP25
U3 small nucleolar RNA-associated protein 25 homolog

1

0

High-throughput

0.458

High

1303167

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.458

High

1310750

PSF3
DNA replication complex GINS protein PSF3

1

0

High-throughput

0.458

High

1335091

S40A1
Solute carrier family 40 member 1

1

0

High-throughput

0.458

High

1335094

DCA16
DDB1- and CUL4-associated factor 16

1

0

High-throughput

0.458

High

254293

LRP4
Low-density lipoprotein receptor-related protein 4

1

4

High-throughput

0.437

High

324050

BAG2
BAG family molecular chaperone regulator 2

1

5

High-throughput

0.437

High

361927

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

3

High-throughput

0.437

High

409561

HEPS
Serine protease hepsin

1

3

High-throughput

0.437

High

506665

BCR
Breakpoint cluster region protein

1

5

High-throughput

0.437

High

877591

CAD15
Cadherin-15

1

2

High-throughput

0.437

High

940675

3BP2
SH3 domain-binding protein 2

1

5

High-throughput

0.437

High

991045

TRHY
Trichohyalin

1

20

High-throughput

0.437

High

1032877

PHLP
Phosducin-like protein

1

1

High-throughput

0.437

High

1061624

CUL7
Cullin-7

1

8

High-throughput

0.437

High

1134772

LITD1
LINE-1 type transposase domain-containing protein 1

1

2

High-throughput

0.437

High

1173315

ANKS3
Ankyrin repeat and SAM domain-containing protein 3

1

11

High-throughput

0.437

High

1174538

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

8

High-throughput

0.437

High

1264929

DNS2B
Deoxyribonuclease-2-beta

1

2

High-throughput

0.437

High

1267493

AP3S1
AP-3 complex subunit sigma-1

1

4

High-throughput

0.437

High

1269023

SORL
Sortilin-related receptor

1

5

High-throughput

0.437

High

1270196

HTRA1
Serine protease HTRA1

1

1

High-throughput

0.437

High

1306418

APBA2
Amyloid-beta A4 precursor protein-binding family A member 2

1

3

High-throughput

0.437

High

1331877

ACTL8
Actin-like protein 8

1

7

High-throughput

0.437

High

1335090

NCK5L
Nck-associated protein 5-like

1

1

High-throughput

0.437

High

1335096

KLH21
Kelch-like protein 21

1

4

High-throughput

0.437

High

1335098

PNMA2
Paraneoplastic antigen Ma2

1

7

High-throughput

0.437

High

792251

MTHR
Methylenetetrahydrofolate reductase

2

0

High-throughput

0.318

High

64562

ZSWM8
Zinc finger SWIM domain-containing protein 8

1

0

High-throughput

0.249

Low

305865

UBL3
Ubiquitin-like protein 3

1

0

Small-scale

0.249

Low

534163

HRES1
Putative HTLV-1-related endogenous sequence

1

0

High-throughput

0.249

Low

826552

DHYS
Deoxyhypusine synthase

1

0

High-throughput

0.249

Low

1115779

CE022
UPF0489 protein C5orf22

1

0

High-throughput

0.249

Low

1327417

SPC1L
Speriolin-like protein

1

0

High-throughput

0.249

Low

1331228

OSBL3
Oxysterol-binding protein-related protein 3

1

0

High-throughput

0.249

Low

1335103

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024