HitPredict

Interactor 1: KBTB8 (Q8NFY9)
Kelch repeat and BTB domain-containing protein 8 (T-cell activation kelch repeat protein) (TA-KRP)
Gene: KBTBD8

Interactor 2: KLH29 (Q96CT2)
Kelch-like protein 29 (Kelch repeat and BTB domain-containing protein 9)
Gene: KLHL29

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BACK~BTB, BTB~BTB, Kelch_1~Kelch_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 601 Hs			1 875
+	Hs
		1262043 KBTB7_HUMAN (10-598): 1.43e-161: 479: 27.66		KLH29_HUMAN (1-875): 0: 904: 100.00
+	Hs
		1201290 KBTB6_HUMAN (11-598): 3.2e-159: 473: 27.39		KLH29_HUMAN (1-875): 0: 904: 100.00
+	Hs
		1121506 KLH26_HUMAN (10-588): 1.15e-142: 428: 22.31		KLHL3_HUMAN (287-872): 4.08e-172: 512: 30.19
+	Hs
		307183 KLH26_HUMAN (10-588): 1.15e-142: 428: 22.31		KLHL2_HUMAN (280-872): 2.54e-170: 508: 28.31
+	Hs
		307225 KLH13_HUMAN (1-588): 8.95e-142: 427: 21.57		KLHL2_HUMAN (280-872): 2.54e-170: 508: 28.31
+	Hs
		1120765 KLH26_HUMAN (10-588): 1.15e-142: 428: 22.31		KLH12_HUMAN (309-871): 8.55e-169: 503: 30.00
+	Hs
		1120822 KLH13_HUMAN (1-588): 8.95e-142: 427: 21.57		KLH12_HUMAN (309-871): 8.55e-169: 503: 30.00
+	Hs
		1121494 KLH26_HUMAN (10-588): 1.15e-142: 428: 22.31		KLH25_HUMAN (290-874): 3.95e-151: 458: 27.76
+	Dm
		980055 KELC_DROME (25-599): 2.58e-135: 431: 23.03		KELC_DROME (685-874): 8.4e-49: 190: 23.71
+	Hs
		1121511 KLH26_HUMAN (10-588): 1.15e-142: 428: 22.31		KLH20_HUMAN (714-874): 2.17e-38: 154: 21.08
+	Hs
		1121499 KLH26_HUMAN (10-588): 1.15e-142: 428: 22.31		KLH28_HUMAN (716-874): 4.2e-35: 143: 19.21
+	Hs
		1121468 KLH26_HUMAN (10-588): 1.15e-142: 428: 22.31		KLH26_HUMAN (547-874): 5.8e-34: 140: 15.01
+	Hs
		1121513 KLH26_HUMAN (10-588): 1.15e-142: 428: 22.31		IPP_HUMAN (729-873): 2.51e-33: 138: 23.08
+	Hs
		1164620 KBTB7_HUMAN (10-598): 1.43e-161: 479: 27.66		KLH24_HUMAN (763-873): 1.43e-13: 76.4: 16.81
+	Hs
		1121507 KLH26_HUMAN (10-588): 1.15e-142: 428: 22.31		KLH21_HUMAN (715-874): 7.47e-23: 106: 18.79
+	Hs
		152492 KLH26_HUMAN (10-588): 1.15e-142: 428: 22.31		ENC1_HUMAN (718-874): 7.63e-22: 102: 17.65
+	Hs
		152500 KLH13_HUMAN (1-588): 8.95e-142: 427: 21.57		ENC1_HUMAN (718-874): 7.63e-22: 102: 17.65
+	Hs
		1121501 KLH26_HUMAN (10-588): 1.15e-142: 428: 22.31		KLHL9_HUMAN (775-874): 1.95e-17: 89.1: 13.59
+	Hs
		1121502 KLH26_HUMAN (10-588): 1.15e-142: 428: 22.31		KLH13_HUMAN (775-874): 2.39e-17: 88.8: 15.53
+	Hs
		1121471 KLH26_HUMAN (10-588): 1.15e-142: 428: 22.31		KLH24_HUMAN (763-873): 1.43e-13: 76.4: 16.81