HitPredict

Interactor 1: PJA1 (Q8NG27)
E3 ubiquitin-protein ligase Praja-1 (Praja1) (EC 2.3.2.27) (RING finger protein 70) (RING-type E3 ubiquitin transferase Praja-1)
Gene: PJA1

Interactor 2: MAGD4 (Q96JG8)
Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen)
Gene: MAGED4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 643 Hs			1 741
+	Hs
		1245320 PJA1_HUMAN (1-643): 1.23e-161: 480: 100.00		MAGD1_HUMAN (68-739): 3.08e-101: 330: 36.51
+	Hs
		180558 PJA1_HUMAN (1-643): 1.23e-161: 480: 100.00		MAGB4_HUMAN (335-629): 4.8e-97: 306: 32.22
+	Hs
		1245291 PJA1_HUMAN (1-643): 1.23e-161: 480: 100.00		NSE3_HUMAN (354-630): 3.45e-92: 291: 33.78
+	Hs
		196369 PJA2_HUMAN (1-642): 1.14e-129: 399: 44.94		MAGD2_HUMAN (150-737): 1.08e-115: 363: 32.46
+	Hs
		196377 PJA2_HUMAN (1-642): 1.14e-129: 399: 44.94		MAGD1_HUMAN (68-739): 3.08e-101: 330: 36.51
+	Mm
		1193497 PJA2_MOUSE (1-642): 1.27e-123: 384: 43.35		MAGD1_MOUSE (57-739): 3.24e-92: 306: 35.56
+	Hs
		196338 PJA2_HUMAN (1-642): 1.14e-129: 399: 44.94		NSE3_HUMAN (354-630): 3.45e-92: 291: 33.78
+	Mm
		223221 PJA1_MOUSE (38-643): 3.77e-116: 360: 74.67		MAGD1_MOUSE (57-739): 3.24e-92: 306: 35.56
+	Mm
		223218 PJA1_MOUSE (38-643): 3.77e-116: 360: 74.67		NECD_MOUSE (290-634): 4.43e-81: 263: 25.15
+	Hs
		1377022 RNF6_HUMAN (1-640): 5.26e-52: 192: 14.82		MAGD1_HUMAN (68-739): 3.08e-101: 330: 36.51
+	Hs
		282757 RNF8_HUMAN (383-639): 1.07e-34: 139: 16.85		MAGD1_HUMAN (68-739): 3.08e-101: 330: 36.51