Protein: TET5B
Terminal nucleotidyltransferase 5B (EC 2.7.7.19) (Non-canonical poly(A) polymerase FAM46B)

Gene: TET5B, TENT5B
Organism: Homo sapiens
Interactions: 87
UniProt ID: Q96A09

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0008285 - negative regulation of cell population proliferation
GO:0043066 - negative regulation of apoptotic process
GO:0045727 - positive regulation of translation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

136119

PLK4
Serine/threonine-protein kinase PLK4

2

3

High-throughput

0.783

High

927474

ATX1
Ataxin-1

5

1

High-throughput

0.722

High

1381902

BCCIP
BRCA2 and CDKN1A-interacting protein

1

3

High-throughput

0.691

High

1139100

DAZP2
DAZ-associated protein 2

3

1

High-throughput

0.671

High

1381896

RHXF2
Rhox homeobox family member 2

3

4

High-throughput

0.667

High

1381901

SH22A
SH2 domain-containing protein 2A

2

2

High-throughput

0.634

High

155015

BHE40
Class E basic helix-loop-helix protein 40

2

2

High-throughput

0.606

High

277129

PROP1
Homeobox protein prophet of Pit-1

2

2

High-throughput

0.606

High

351454

TBX6
T-box transcription factor TBX6

2

2

High-throughput

0.606

High

370751

FOS
Protein c-Fos

2

1

High-throughput

0.606

High

505752

ZN688
Zinc finger protein 688

2

1

High-throughput

0.606

High

700473

PSB8
Proteasome subunit beta type-8

2

3

High-throughput

0.606

High

912994

HNRPF
Heterogeneous nuclear ribonucleoprotein F

2

3

High-throughput

0.606

High

921053

FOSB
Protein FosB

2

1

High-throughput

0.606

High

1091240

FOXI1
Forkhead box protein I1

2

2

High-throughput

0.606

High

1151037

PCH2
Pachytene checkpoint protein 2 homolog

2

1

High-throughput

0.606

High

1180800

KLH38
Kelch-like protein 38

2

2

High-throughput

0.606

High

1224879

TENS2
Tensin-2

2

1

High-throughput

0.606

High

1253073

ZN620
Zinc finger protein 620

2

1

High-throughput

0.606

High

1381893

ZC3HA
Zinc finger CCCH domain-containing protein 10

2

1

High-throughput

0.606

High

1381905

UBQL2
Ubiquilin-2

2

3

High-throughput

0.606

High

1381892

TET5A
Terminal nucleotidyltransferase 5A

1

0

High-throughput

0.589

High

733263

OTX2
Homeobox protein OTX2

2

0

High-throughput

0.580

High

1007971

PO6F2
POU domain, class 6, transcription factor 2

2

0

High-throughput

0.580

High

1061805

TLE5
TLE family member 5

2

0

High-throughput

0.580

High

1093679

MKRN3
E3 ubiquitin-protein ligase makorin-3

2

0

High-throughput

0.580

High

1207246

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

2

0

High-throughput

0.580

High

1213525

UBAP2
Ubiquitin-associated protein 2

2

0

High-throughput

0.580

High

1253971

RBPS2
RNA-binding protein with multiple splicing 2

2

0

High-throughput

0.580

High

1301006

RFX6
DNA-binding protein RFX6

2

0

High-throughput

0.580

High

1356307

SMAP2
Stromal membrane-associated protein 2

2

0

High-throughput

0.580

High

1381890

ZN503
Zinc finger protein 503

2

0

High-throughput

0.580

High

1381891

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

2

0

High-throughput

0.580

High

1381894

SPAG8
Sperm-associated antigen 8

2

0

High-throughput

0.580

High

1381899

RUSC1
AP-4 complex accessory subunit RUSC1

2

0

High-throughput

0.580

High

1381906

AKP8L
A-kinase anchor protein 8-like

2

0

High-throughput

0.580

High

1186680

KRA62
Keratin-associated protein 6-2

2

1

High-throughput

0.553

High

1211141

CJ055
Uncharacterized protein C10orf55

2

1

High-throughput

0.553

High

1328894

ZBTB2
Zinc finger and BTB domain-containing protein 2

2

1

High-throughput

0.553

High

776107

SOX5
Transcription factor SOX-5

1

0

High-throughput

0.549

High

384507

CRYAA
Alpha-crystallin A chain

1

1

High-throughput

0.515

High

415769

HSPB1
Heat shock protein beta-1

1

1

High-throughput

0.515

High

1245290

Q6PJH3
A kinase

1

1

High-throughput

0.515

High

1381903

RIM3A
RIMS-binding protein 3A

1

1

High-throughput

0.515

High

131001

HIP1
Huntingtin-interacting protein 1

1

0

High-throughput

0.493

High

246081

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.493

High

301609

WFS1
Wolframin

1

0

High-throughput

0.493

High

442429

GELS
Gelsolin

1

0

High-throughput

0.493

High

702489

CLAT
Choline O-acetyltransferase

1

0

High-throughput

0.493

High

843842

HD
Huntingtin

1

0

High-throughput

0.493

High

937081

CASP6
Caspase-6

1

0

High-throughput

0.493

High

954569

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.493

High

981628

RAN
GTP-binding nuclear protein Ran

1

0

High-throughput

0.493

High

1289867

Q86V38
Atrophin 1

1

0

High-throughput

0.493

High

1369670

KLK6
Kallikrein-6

1

0

High-throughput

0.493

High

1381908

RNF11
RING finger protein 11

1

0

High-throughput

0.493

High

66401

RIM3C
RIMS-binding protein 3C

1

1

High-throughput

0.481

High

1134838

NR1D2
Nuclear receptor subfamily 1 group D member 2

1

3

High-throughput

0.481

High

331216

KI20A
Kinesin-like protein KIF20A

1

1

High-throughput

0.479

High

1381907

FND3A
Fibronectin type-III domain-containing protein 3A

1

3

High-throughput

0.479

High

650336

FGFR3
Fibroblast growth factor receptor 3

1

1

High-throughput

0.470

High

1237998

Q6NSM0
NR1D2 protein

1

1

High-throughput

0.470

High

586334

ZEP1
Zinc finger protein 40

1

0

High-throughput

0.460

High

959511

YPEL3
Protein yippee-like 3

1

1

High-throughput

0.439

High

1381895

AKAP9
A-kinase anchor protein 9

1

1

High-throughput

0.439

High

50346

F168B
Myelin-associated neurite-outgrowth inhibitor

2

0

High-throughput

0.316

High

70408

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

70930

CMI2B
Ciliary microtubule inner protein 2B

2

0

High-throughput

0.316

High

300456

KRT34
Keratin, type I cuticular Ha4

2

0

High-throughput

0.316

High

1041458

ACY1
Aminoacylase-1

2

0

High-throughput

0.316

High

1157187

S15A2
Solute carrier family 15 member 2

2

0

High-throughput

0.316

High

1160369

OBF1
POU domain class 2-associating factor 1

2

0

High-throughput

0.316

High

1186586

KRA61
Keratin-associated protein 6-1

2

0

High-throughput

0.316

High

1186843

KR196
Keratin-associated protein 19-6

2

0

High-throughput

0.316

High

1187437

CC036
Uncharacterized protein C3orf36

2

0

High-throughput

0.316

High

1212681

GT253
Inactive glycosyltransferase 25 family member 3

2

0

High-throughput

0.316

High

1240922

S27A4
Long-chain fatty acid transport protein 4

2

0

High-throughput

0.316

High

1258158

UBP54
Ubiquitin carboxyl-terminal hydrolase 54

2

0

High-throughput

0.316

High

1363747

PSMF1
Proteasome inhibitor PI31 subunit

2

0

High-throughput

0.316

High

1381898

NICN1
Nicolin-1

2

0

High-throughput

0.316

High

1381900

ENKD1
Enkurin domain-containing protein 1

2

0

High-throughput

0.316

High

1381904

HMGX4
HMG domain-containing protein 4

2

0

High-throughput

0.316

High

223857

NDUA2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2

1

0

High-throughput

0.279

Low

1381889

COA7
Cytochrome c oxidase assembly factor 7

1

0

High-throughput

0.279

Low

1381897

PAAF1
Proteasomal ATPase-associated factor 1

1

0

High-throughput

0.279

Low

1381909

Q9Y649
GW128

1

0

High-throughput

0.268

Low

1191386

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025