HitPredict

Interactor 1: NEDD1 (Q8NHV4)
Protein NEDD1 (Neural precursor cell expressed developmentally down-regulated protein 1) (NEDD-1)
Gene: NEDD1

Interactor 2: GCP4 (Q9UGJ1)
Gamma-tubulin complex component 4 (GCP-4) (hGCP4) (Gamma-ring complex protein 76 kDa) (h76p) (hGrip76)
Gene: TUBGCP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26496610, 33961781, 23443559
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000278 - mitotic cell cycle GO:0000922 - spindle pole GO:0005813 - centrosome GO:0005829 - cytosol GO:0007020 - microtubule nucleation and 1 others more... GO:0043015 - gamma-tubulin binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 660 Hs			1 667
+	Hs
		1246004 NEDD1_HUMAN (1-660): 7.8e-168: 496: 98.49		GCP3_HUMAN (1-662): 2.3e-169: 509: 16.78
+	Hs
		1246020 NEDD1_HUMAN (1-660): 7.8e-168: 496: 98.49		GCP2_HUMAN (1-664): 2.74e-169: 508: 18.06
+	Hs
		1246013 NEDD1_HUMAN (1-660): 7.8e-168: 496: 98.49		GCP5_HUMAN (1-649): 1.21e-132: 417: 15.64
+	Hs
		1246012 NEDD1_HUMAN (1-660): 7.8e-168: 496: 98.49		GCP6_HUMAN (1-408): 7.41e-75: 264: 13.26
+	Hs
		197081 PRP4_HUMAN (73-361): 3.77e-67: 230: 15.28		GCP2_HUMAN (1-664): 2.74e-169: 508: 18.06
+	Dm
		1368457 Q9VJ57_DROME (81-397): 3.29e-56: 203: 19.94		GCP3_DROME (1-663): 2.07e-136: 424: 17.59
+	Hs
		1301479 KTNB1_HUMAN (204-597): 8.28e-32: 133: 12.65		GCP6_HUMAN (1-408): 7.41e-75: 264: 13.26
+	Hs
		91448 KTNB1_HUMAN (204-597): 8.28e-32: 133: 12.65		E7EQL8_HUMAN (1-408): 6.33e-75: 264: 13.26