HitPredict

Interactor 1: TPC2 (Q8NHX9)
Two pore channel protein 2 (Two pore calcium channel protein 2)
Gene: TPCN2

Interactor 2: ANR27 (Q96NW4)
Ankyrin repeat domain-containing protein 27 (VPS9 domain-containing protein)
Gene: ANKRD27

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005764 - lysosome GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 752 Hs			1 1050
+	Hs
		1044901 CAC1S_HUMAN (396-748): 2.09e-35: 146: 16.02		TNKS2_HUMAN (107-816): 5.68e-95: 329: 15.46
+	Hs
		310051 CAC1S_HUMAN (396-748): 2.09e-35: 146: 16.02		TNKS1_HUMAN (695-1049): 1.3e-58: 222: 19.25
+	Hs
		1021401 SCN5A_HUMAN (428-682): 9.3e-23: 106: 13.28		ANK3_HUMAN (10-404): 9.35e-28: 124: 7.60
+	Rn
		251017 SCN8A_RAT (418-724): 2.46e-23: 108: 16.29		ANK3_RAT (10-404): 7.26e-27: 121: 6.55
+	Rn
		251018 SCN1A_RAT (418-724): 6.72e-19: 94.2: 15.59		ANK3_RAT (10-404): 7.26e-27: 121: 6.55
+	Rn
		251019 SCN2A_RAT (418-724): 3.13e-18: 92.2: 14.49		ANK3_RAT (10-404): 7.26e-27: 121: 6.55