Interactor 1: COP1 (Q8NHY2)
E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1) (RING finger and WD repeat domain protein 2) (RING finger protein 200) (RING-type E3 ubiquitin transferase RFWD2)
Gene: COP1
Interactor 2: TRIB1 (Q96RU8)
Tribbles homolog 1 (TRB-1) (G-protein-coupled receptor-induced gene 2 protein) (GIG-2) (SKIP1)
Gene: TRIB1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 0.60 | 0.755 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27041596, 28514442, 28089446, 29296815, 30692133, 33961781, 32707033, 25117710 |
| Identification Methods | affinity chromatography technology, unspecified method, x-ray crystallography, anti tag coimmunoprecipitation, pull down, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005829 - cytosol GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
| Homologous interactions | 12 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
