Protein: IQGA1
Ras GTPase-activating-like protein IQGAP1

Gene: IQGA1, Iqgap1
Organism: Mus musculus
Interactions: 32
UniProt ID: Q9JKF1

Gene Ontology (top 5):
GO:0001726 - ruffle
GO:0001817 - regulation of cytokine production
GO:0005078 - MAP-kinase scaffold activity
GO:0005509 - calcium ion binding
GO:0005516 - calmodulin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

104645

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

14

High-throughput

0.691

High

1190209

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

19

High-throughput

0.691

High

700381

BRAF
Serine/threonine-protein kinase B-raf

1

15

High-throughput

0.618

High

953814

CDC42
Cell division control protein 42 homolog

1

20

Small-scale

0.618

High

988916

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

Small-scale

0.618

High

1022229

SHC1
SHC-transforming protein 1

1

20

Small-scale

0.589

High

1317851

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.586

High

1240191

HDAC4
Histone deacetylase 4

1

6

High-throughput

0.536

High

1274454

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

4

High-throughput

0.536

High

236639

ITB3
Integrin beta-3

1

1

High-throughput

0.501

High

478559

ITB1
Integrin beta-1

1

1

High-throughput

0.501

High

312590

MEN1
Menin

1

1

Small-scale

0.479

High

928089

ATX1
Ataxin-1

1

2

High-throughput

0.479

High

988941

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

7

Small-scale

0.479

High

1257449

SPOP
Speckle-type POZ protein

1

3

High-throughput

0.479

High

1282678

FACD2
Fanconi anemia group D2 protein homolog

1

3

High-throughput

0.479

High

1295918

DMRT2
Doublesex- and mab-3-related transcription factor 2

1

1

Small-scale

0.479

High

1296393

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

8

High-throughput

0.479

High

1362375

WASL
Actin nucleation-promoting factor WASL

1

6

Small-scale

0.479

High

1362770

EED
Polycomb protein EED

1

4

High-throughput

0.479

High

1362924

CLIP1
CAP-Gly domain-containing linker protein 1

1

16

Small-scale

0.479

High

1424118

KLH40
Kelch-like protein 40

1

2

Small-scale

0.479

High

1353966

ELF5
ETS-related transcription factor Elf-5

1

0

High-throughput

0.458

High

1408692

FOXP3
Forkhead box protein P3

1

0

High-throughput

0.458

High

548974

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

11

High-throughput

0.457

High

811890

TRAF1
TNF receptor-associated factor 1

1

4

High-throughput

0.457

High

450414

CSF1
Macrophage colony-stimulating factor 1

1

7

Small-scale

0.445

High

651581

CBL
E3 ubiquitin-protein ligase CBL

1

6

High-throughput

0.445

High

1189186

STING
Stimulator of interferon genes protein

1

1

High-throughput

0.445

High

97661

E9PV60
WD repeat and FYVE domain containing 4

1

6

High-throughput

0.437

High

1298365

MT21E
Protein-lysine methyltransferase METTL21E

1

3

High-throughput

0.437

High

399164

CFAD
Complement factor D

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025