HitPredict

Interactor 1: IL31R (Q8NI17)
Interleukin-31 receptor subunit alpha (IL-31 receptor subunit alpha) (IL-31R subunit alpha) (IL-31R-alpha) (IL-31RA) (Cytokine receptor-like 3) (GLM-R) (hGLM-R) (Gp130-like monocyte receptor) (Gp130-like receptor) (ZcytoR17)
Gene: IL31RA

Interactor 2: PKP3 (Q9Y446)
Plakophilin-3
Gene: PKP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 797
+	Hs
		489914 PTPRF_HUMAN (16-344): 7.37e-28: 123: 14.46		CTNB1_HUMAN (101-739): 1.82e-106: 346: 16.11
+	Hs
		542483 FND3A_HUMAN (229-732): 1.75e-31: 134: 14.71		PLAK_HUMAN (114-739): 1.02e-90: 303: 15.13
+	Mm
		56908 PTPRF_MOUSE (1-268): 7.7e-18: 90.8: 10.91		CTNB1_MOUSE (101-739): 2.27e-106: 345: 16.11
+	Hs
		489895 PTPRF_HUMAN (16-344): 7.37e-28: 123: 14.46		PLAK_HUMAN (114-739): 1.02e-90: 303: 15.13
+	Dm
		333111 SDK_DROME (24-501): 4.1e-16: 85.3: 15.66		ARM_DROME (92-793): 1e-98: 327: 14.59
+	Hs
		234460 DSCAM_HUMAN (20-501): 3.13e-23: 108: 15.25		APCL_HUMAN (334-541): 7.71e-10: 64.8: 22.12
+	Rn
		1145481 PTPRF_RAT (1-268): 3.88e-17: 88.5: 11.27		CTNB1_RAT (142-506): 1.72e-10: 66.6: 14.10