Protein: DEAD
ATP-dependent RNA helicase DeaD (EC 3.6.4.13) (Cold-shock DEAD box protein A) (Translation factor W2)

Gene: DEAD
Organism: Escherichia coli K-12
Interactions: 100
UniProt ID: P0A9P6

Gene Ontology (top 5):
GO:0000027 - ribosomal large subunit assembly
GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006401 - RNA catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

497105

SRMB
ATP-dependent RNA helicase SrmB

2

18

High-throughput

0.759

High

497114

HRPA
ATP-dependent RNA helicase HrpA

2

6

High-throughput

0.759

High

492864

RL27
Large ribosomal subunit protein bL27

2

0

High-throughput

0.720

High

497070

DEAD
ATP-dependent RNA helicase DeaD

1

16

High-throughput

0.698

High

497106

RNE
Ribonuclease E

3

1

Small-scale

0.634

High

492699

RL1
Large ribosomal subunit protein uL1

1

2

High-throughput

0.625

High

497088

GYRB
DNA gyrase subunit B

1

0

High-throughput

0.593

High

489290

ACP
Acyl carrier protein

2

1

High-throughput

0.588

High

492906

RL28
Large ribosomal subunit protein bL28

2

1

High-throughput

0.588

High

493306

RS11
Small ribosomal subunit protein uS11

2

5

High-throughput

0.588

High

493569

RS19
Small ribosomal subunit protein uS19

2

5

High-throughput

0.588

High

496249

CSPD
Cold shock-like protein CspD

2

16

High-throughput

0.588

High

497079

DBHB
DNA-binding protein HU-beta

2

3

High-throughput

0.588

High

497082

RL16
Large ribosomal subunit protein uL16

2

1

High-throughput

0.588

High

497096

RL6
Large ribosomal subunit protein uL6

2

2

High-throughput

0.588

High

497107

PSS
CDP-diacylglycerol--serine O-phosphatidyltransferase PssA

1

0

High-throughput

0.586

High

497075

YBCJ
Putative RNA-binding protein YbcJ

2

0

High-throughput

0.576

High

492426

RL11
Large ribosomal subunit protein uL11

2

0

High-throughput

0.563

High

494881

TGT
Queuine tRNA-ribosyltransferase

2

0

High-throughput

0.563

High

495214

YBAB
Nucleoid-associated protein YbaB

2

0

High-throughput

0.563

High

497083

RL23
Large ribosomal subunit protein uL23

2

0

High-throughput

0.563

High

497091

NUSG
Transcription termination/antitermination protein NusG

2

0

High-throughput

0.563

High

497094

RL17
Large ribosomal subunit protein bL17

2

0

High-throughput

0.563

High

497103

RL18
Large ribosomal subunit protein uL18

2

0

High-throughput

0.563

High

497111

RLMN
Dual-specificity RNA methyltransferase RlmN

2

0

High-throughput

0.563

High

497121

RS21
Small ribosomal subunit protein bS21

2

0

High-throughput

0.563

High

497099

RS1
Small ribosomal subunit protein bS1

2

6

High-throughput

0.537

High

497110

CBPA
Curved DNA-binding protein

2

2

High-throughput

0.537

High

382667

RS7
Small ribosomal subunit protein uS7

1

3

High-throughput

0.484

High

473264

DNAJ
Chaperone protein DnaJ

1

3

High-throughput

0.484

High

493219

RS10
Small ribosomal subunit protein uS10

1

7

High-throughput

0.484

High

493367

RS13
Small ribosomal subunit protein uS13

1

5

High-throughput

0.484

High

493533

RS18
Small ribosomal subunit protein bS18

1

1

High-throughput

0.484

High

493872

RS3
Small ribosomal subunit protein uS3

1

6

High-throughput

0.484

High

494053

RS4
Small ribosomal subunit protein uS4

1

1

High-throughput

0.484

High

494252

RS5
Small ribosomal subunit protein uS5

1

8

High-throughput

0.484

High

494370

RS8
Small ribosomal subunit protein uS8

1

6

High-throughput

0.484

High

494416

RS9
Small ribosomal subunit protein uS9

1

5

High-throughput

0.484

High

497071

CSPA
Cold shock protein CspA

1

16

High-throughput

0.484

High

497072

CSPC
Cold shock-like protein CspC

1

16

High-throughput

0.484

High

497073

RL13
Large ribosomal subunit protein uL13

1

5

High-throughput

0.484

High

497074

RLUC
Ribosomal large subunit pseudouridine synthase C

1

2

High-throughput

0.484

High

497078

DBHA
DNA-binding protein HU-alpha

1

3

High-throughput

0.484

High

497085

MAP1
Methionine aminopeptidase

1

1

High-throughput

0.484

High

497104

RNR
Ribonuclease R

1

5

High-throughput

0.484

High

497113

RLUB
Ribosomal large subunit pseudouridine synthase B

1

2

High-throughput

0.484

High

497115

RL2
Large ribosomal subunit protein uL2

1

7

High-throughput

0.484

High

497116

RL3
Large ribosomal subunit protein uL3

1

4

High-throughput

0.484

High

497118

RL4
Large ribosomal subunit protein uL4

1

2

High-throughput

0.484

High

497119

RL22
Large ribosomal subunit protein uL22

1

6

High-throughput

0.484

High

497128

SUFC
Probable ATP-dependent transporter SufC

1

1

High-throughput

0.484

High

421109

PNP
Polyribonucleotide nucleotidyltransferase

1

5

High-throughput

0.479

High

458779

FDHF
Formate dehydrogenase H

1

1

High-throughput

0.479

High

496276

CSPE
Cold shock-like protein CspE

1

16

High-throughput

0.479

High

497120

RL5
Large ribosomal subunit protein uL5

1

3

High-throughput

0.479

High

382561

RS6
Small ribosomal subunit protein bS6

1

0

High-throughput

0.464

High

490639

FABA
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase

1

0

High-throughput

0.464

High

490871

HFQ
RNA-binding protein Hfq

1

0

High-throughput

0.464

High

492127

HSLV
ATP-dependent protease subunit HslV

1

0

High-throughput

0.464

High

492585

RL19
Large ribosomal subunit protein bL19

1

0

High-throughput

0.464

High

493140

RL9
Large ribosomal subunit protein bL9

1

0

High-throughput

0.464

High

493611

RS20
Small ribosomal subunit protein bS20

1

0

High-throughput

0.464

High

496715

PHOL
PhoH-like protein

1

0

High-throughput

0.464

High

497076

ACCA
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha

1

0

High-throughput

0.464

High

497080

EVGA
DNA-binding transcriptional activator EvgA

1

0

High-throughput

0.464

High

497084

RS15
Small ribosomal subunit protein uS15

1

0

High-throughput

0.464

High

497086

DACA
D-alanyl-D-alanine carboxypeptidase DacA

1

0

High-throughput

0.464

High

497089

INGK
Guanosine-inosine kinase

1

0

High-throughput

0.464

High

497092

ODP1
Pyruvate dehydrogenase E1 component

1

0

High-throughput

0.464

High

497093

SPOT
Bifunctional

1

0

High-throughput

0.464

High

497095

RL21
Large ribosomal subunit protein bL21

1

0

High-throughput

0.464

High

497100

SUCD
Succinate--CoA ligase [ADP-forming] subunit alpha

1

0

High-throughput

0.464

High

497101

YFIF
Uncharacterized tRNA/rRNA methyltransferase YfiF

1

0

High-throughput

0.464

High

497102

URAA
Uracil permease

1

0

High-throughput

0.464

High

497112

RLMJ
Ribosomal RNA large subunit methyltransferase J

1

0

High-throughput

0.464

High

497117

RL24
Large ribosomal subunit protein uL24

1

0

High-throughput

0.464

High

497129

BGLA
6-phospho-beta-glucosidase BglA

1

0

High-throughput

0.464

High

492822

RL20
Large ribosomal subunit protein bL20

1

0

High-throughput

0.458

High

495963

YFBU
UPF0304 protein YfbU

1

0

High-throughput

0.458

High

497081

YIBL
Uncharacterized protein YibL

1

0

High-throughput

0.458

High

497090

RRAB
Regulator of ribonuclease activity B

1

0

High-throughput

0.458

High

497122

CSRA
Carbon storage regulator

1

0

High-throughput

0.458

High

493470

RS16
Small ribosomal subunit protein bS16

1

1

High-throughput

0.442

High

493706

RS2
Small ribosomal subunit protein uS2

1

9

High-throughput

0.442

High

497098

RS17
Small ribosomal subunit protein uS17

1

4

High-throughput

0.437

High

497127

YNFE
Putative dimethyl sulfoxide reductase chain YnfE

1

1

High-throughput

0.437

High

491928

RPPH
RNA pyrophosphohydrolase

2

0

High-throughput

0.307

High

494557

RNPA
Ribonuclease P protein component

2

0

High-throughput

0.307

High

495431

TRMB
tRNA

2

0

High-throughput

0.307

High

497077

DPS
DNA protection during starvation protein

2

0

High-throughput

0.307

High

497123

HCP
Hydroxylamine reductase

2

0

High-throughput

0.307

High

497087

DPPC
Dipeptide transport system permease protein DppC

1

0

High-throughput

0.253

Low

497097

RS14
Small ribosomal subunit protein uS14

1

0

High-throughput

0.253

Low

497108

3PASE
Inorganic triphosphatase

1

0

High-throughput

0.253

Low

497109

SQASE
Sulfoquinovosidase

1

0

High-throughput

0.253

Low

497124

RLMKL
Ribosomal RNA large subunit methyltransferase K/L [Includes: 23S rRNA m2G2445 methyltransferase

1

0

High-throughput

0.253

Low

497126

SIXA
Phosphohistidine phosphatase SixA

1

0

High-throughput

0.253

Low

384012

RL15
Large ribosomal subunit protein uL15

1

0

High-throughput

0.249

Low

497125

YNCE
Uncharacterized protein YncE

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025