HitPredict

Interactor 1: RICTR (Q6QI06)
Rapamycin-insensitive companion of mTOR (AVO3 homolog) (mAVO3) (Protein pianissimo)
Gene: Rictor

Interactor 2: SIN1 (Q8BKH7)
Target of rapamycin complex 2 subunit MAPKAP1 (TORC2 subunit MAPKAP1) (Mitogen-activated protein kinase 2-associated protein 1) (Stress-activated map kinase-interacting protein 1) (SAPK-interacting protein 1)
Gene: Mapkap1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	1.00	0.962

The method score is based on:

Property	Details
Experiments	18566586, 18851840, 27340174, 22609986, 22307628, 18925875, 18505677
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	RICTOR_N~SIN1
Common GO terms	GO:0005764 - lysosome GO:0005765 - lysosomal membrane GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane and 9 others more... GO:0007010 - cytoskeleton organization GO:0019901 - protein kinase binding GO:0030307 - positive regulation of cell growth GO:0031669 - cellular response to nutrient levels GO:0031932 - TORC2 complex GO:0038203 - TORC2 signaling GO:0043066 - negative regulation of apoptotic process GO:0140767 - enzyme-substrate adaptor activity GO:1902554 - serine/threonine protein kinase complex
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	1708
Mm

1	522

Service provided by Combinatics, Japan

Last updated: 11Aug2025