HitPredict

Interactor 1: TRAK2 (Q8R2H7)
Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein homolog) (GABA-A receptor-interacting factor 1) (GRIF-1) (O-GlcNAc transferase-interacting protein of 98 kDa)
Gene: TRAK2

Interactor 2: HGS (Q9JJ50)
Hepatocyte growth factor-regulated tyrosine kinase substrate (SNAP-25-interacting protein Hrs-2)
Gene: HGS

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17062640
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005769 - early endosome GO:0008333 - endosome to lysosome transport
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 913 Rn			1 776
+	Rn
		869356 HAP1_RAT (93-408): 7.36e-30: 128: 24.93		HGS_RAT (1-776): 1.97e-120: 382: 100.00
+	Hs
		159934 HAP1_HUMAN (121-387): 5.78e-28: 122: 32.35		HGS_HUMAN (1-776): 2.37e-120: 381: 93.31
+	Mm
		193279 HAP1_MOUSE (93-410): 6.01e-30: 128: 23.91		HGS_MOUSE (1-776): 4.81e-114: 365: 97.42
+	Hs
		160234 TRAK1_HUMAN (1-230): 1.71e-10: 67.2: 11.49		HGS_HUMAN (1-776): 2.37e-120: 381: 93.31
+	Hs
		522569 MYH1_HUMAN (1-656): 2.87e-22: 105: 10.21		RBNS5_HUMAN (144-772): 1.47e-48: 186: 13.95
+	Hs
		522643 MYH7_HUMAN (2-541): 1.78e-20: 99: 9.60		RBNS5_HUMAN (144-772): 1.47e-48: 186: 13.95
+	Hs
		725046 MYH9_HUMAN (10-650): 3.46e-24: 111: 9.61		GGA3_HUMAN (6-670): 1.5e-38: 155: 13.76
+	Hs
		724978 MYH9_HUMAN (10-650): 3.46e-24: 111: 9.61		RUFY1_HUMAN (3-228): 9.59e-38: 152: 17.96
+	Hs
		725059 MYH9_HUMAN (10-650): 3.46e-24: 111: 9.61		GGA1_HUMAN (5-149): 1.16e-30: 130: 28.67
+	Hs
		277059 DCTN1_HUMAN (138-506): 2.82e-13: 76.2: 10.51		STAM2_HUMAN (4-521): 1.15e-38: 153: 15.00
+	Hs
		1051426 DCTN1_HUMAN (138-506): 2.82e-13: 76.2: 10.51		RUFY1_HUMAN (3-228): 9.59e-38: 152: 17.96