HitPredict

Interactor 1: Q8SYU5 (Q8SYU5)
RE33762p
Gene: DmelCG10086

Interactor 2: SMUF1 (Q9V853)
E3 ubiquitin-protein ligase Smurf1 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase Smurf1) (Lethal with a checkpoint kinase protein) (SMAD ubiquitination regulatory factor 1 homolog) (DSmurf)
Gene: Smurf

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	38270169
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 469 Dm			1 1061
+	Hs
		1285052 ARRD3_HUMAN (3-409): 1.97e-106: 324: 19.86		NED4L_HUMAN (9-1059): 0: 718: 27.34
+	Hs
		808216 ARRD3_HUMAN (3-409): 1.97e-106: 324: 19.86		NEDD4_HUMAN (83-1059): 0: 640: 25.65
+	Dm
		89895 Q8SYU5_DROME (1-469): 4.34e-151: 440: 100.00		D5SHR3_DROME (638-1061): 6.12e-175: 520: 42.33
+	Dm
		1249359 Q8SYU5_DROME (1-469): 4.34e-151: 440: 100.00		Q9W325_DROME (641-1061): 1.29e-172: 514: 42.62
+	Hs
		1192131 ARRD2_HUMAN (3-400): 1.47e-99: 306: 19.65		HUWE1_HUMAN (360-1060): 2.21e-169: 555: 27.27
+	Dm
		89897 Q9I7L0_DROME (1-450): 6.85e-112: 338: 31.68		D5SHR3_DROME (638-1061): 6.12e-175: 520: 42.33
+	Dm
		1337204 Q9I7L0_DROME (1-450): 6.85e-112: 338: 31.68		Q9W325_DROME (641-1061): 1.29e-172: 514: 42.62
+	Dm
		89904 Q9VI00_DROME (1-465): 1.43e-99: 307: 22.32		D5SHR3_DROME (638-1061): 6.12e-175: 520: 42.33
+	Dm
		1367630 Q9VI00_DROME (1-465): 1.43e-99: 307: 22.32		Q9W325_DROME (641-1061): 1.29e-172: 514: 42.62
+	Dm
		115611 Q8SYU5_DROME (1-469): 4.34e-151: 440: 100.00		M9PFK2_DROME (9-597): 1.22e-46: 184: 15.72
+	Dm
		1249345 Q8SYU5_DROME (1-469): 4.34e-151: 440: 100.00		NEDD4_DROME (9-561): 1.24e-40: 164: 15.15
+	Dm
		115614 Q9VI00_DROME (1-465): 1.43e-99: 307: 22.32		M9PFK2_DROME (9-597): 1.22e-46: 184: 15.72
+	Hs
		1285070 ARRD3_HUMAN (3-409): 1.97e-106: 324: 19.86		WWP1_HUMAN (9-593): 2.45e-37: 154: 17.09
+	Dm
		1367624 Q9VI00_DROME (1-465): 1.43e-99: 307: 22.32		NEDD4_DROME (9-561): 1.24e-40: 164: 15.15
+	Hs
		1285047 ARRD3_HUMAN (3-409): 1.97e-106: 324: 19.86		ITCH_HUMAN (12-550): 4.3e-27: 121: 12.16
+	Hs
		1285085 ARRD3_HUMAN (3-409): 1.97e-106: 324: 19.86		HECW2_HUMAN (20-710): 3.27e-25: 115: 12.94
+	Dm
		1367634 Q9VI00_DROME (1-465): 1.43e-99: 307: 22.32		SUDX_DROME (10-547): 2.68e-30: 131: 12.00
+	Hs
		125633 ARRD3_HUMAN (3-409): 1.97e-106: 324: 19.86		WWP2_HUMAN (7-547): 9.03e-20: 97.5: 13.43
+	Ce
		1341514 Q9XXI4_CAEEL (5-442): 1.81e-108: 329: 22.00		WWP1_CAEEL (6-362): 2.44e-13: 76.7: 15.39
+	Hs
		125595 ARRD2_HUMAN (3-400): 1.47e-99: 306: 19.65		WWP2_HUMAN (7-547): 9.03e-20: 97.5: 13.43