Protein: TLE4
Transducin-like enhancer protein 4 (Grg-4) (Groucho-related protein 4)

Gene: TLE4
Organism: Homo sapiens
Interactions: 69
UniProt ID: Q04727

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003682 - chromatin binding
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

980586

TLE1
Transducin-like enhancer protein 1

4

18

Small-scale

0.886

High

980674

TLE2
Transducin-like enhancer protein 2

3

18

High-throughput

0.861

High

980730

TLE3
Transducin-like enhancer protein 3

3

18

High-throughput

0.847

High

980928

TLE5
TLE family member 5

3

16

High-throughput

0.847

High

980958

TBX20
T-box transcription factor TBX20

3

20

High-throughput

0.656

High

971652

PAX5
Paired box protein Pax-5

2

20

Small-scale

0.636

High

980926

HME1
Homeobox protein engrailed-1

2

20

High-throughput

0.628

High

153649

ANM5
Protein arginine N-methyltransferase 5

1

5

Small-scale

0.618

High

980952

MEP50
Methylosome protein WDR77

1

17

Small-scale

0.618

High

980953

KPCD2
Serine/threonine-protein kinase D2

1

15

High-throughput

0.618

High

308077

VENTX
Homeobox protein VENTX

2

20

High-throughput

0.611

High

822799

TNNI2
Troponin I, fast skeletal muscle

2

3

High-throughput

0.611

High

980929

RIPP1
Protein ripply1

2

19

High-throughput

0.611

High

980933

HLX
H2.0-like homeobox protein

2

20

High-throughput

0.611

High

980936

ISX
Intestine-specific homeobox

2

20

High-throughput

0.611

High

980940

RIPP2
Protein ripply2

2

19

High-throughput

0.611

High

980943

ARMC8
Armadillo repeat-containing protein 8

2

7

High-throughput

0.611

High

740136

NUP62
Nuclear pore glycoprotein p62

2

18

High-throughput

0.606

High

980939

CC183
Coiled-coil domain-containing protein 183

3

6

High-throughput

0.599

High

447473

PO2F2
POU domain, class 2, transcription factor 2

1

18

Small-scale

0.561

High

764630

CUX1
Homeobox protein cut-like 1

1

20

Small-scale

0.561

High

980947

ZMY19
Zinc finger MYND domain-containing protein 19

2

1

High-throughput

0.558

High

980937

EIPR1
EARP and GARP complex-interacting protein 1

1

19

High-throughput

0.553

High

980941

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.553

High

980944

RHG24
Rho GTPase-activating protein 24

1

5

High-throughput

0.553

High

749405

BRCA1
Breast cancer type 1 susceptibility protein

1

15

High-throughput

0.552

High

836823

DNLI4
DNA ligase 4

1

1

High-throughput

0.552

High

49243

FEZF1
Fez family zinc finger protein 1

1

2

High-throughput

0.536

High

315171

SIX6
Homeobox protein SIX6

1

20

High-throughput

0.536

High

868441

ATX1
Ataxin-1

1

7

High-throughput

0.536

High

883098

DSCR6
Protein ripply3

1

19

High-throughput

0.536

High

980942

MAEA
E3 ubiquitin-protein transferase MAEA

1

2

High-throughput

0.536

High

980948

HES6
Transcription cofactor HES-6

1

20

High-throughput

0.536

High

980951

FOXB1
Forkhead box protein B1

1

20

High-throughput

0.536

High

980955

UBIP1
Upstream-binding protein 1

1

5

High-throughput

0.536

High

358746

CRYAA
Alpha-crystallin A chain

1

3

High-throughput

0.501

High

942608

SRPK2
SRSF protein kinase 2

1

20

High-throughput

0.501

High

323705

BAG2
BAG family molecular chaperone regulator 2

1

4

High-throughput

0.489

High

875827

MFAP4
Microfibril-associated glycoprotein 4

1

7

High-throughput

0.489

High

943198

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.489

High

171019

TBXT
T-box transcription factor T

1

20

High-throughput

0.479

High

211840

TLX3
T-cell leukemia homeobox protein 3

1

20

High-throughput

0.479

High

213323

TLX2
T-cell leukemia homeobox protein 2

1

20

High-throughput

0.479

High

271756

PRDM1
PR domain zinc finger protein 1

1

6

High-throughput

0.479

High

487357

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

575391

EGR1
Early growth response protein 1

1

6

High-throughput

0.479

High

620144

PAX7
Paired box protein Pax-7

1

20

High-throughput

0.479

High

620331

GATA2
Endothelial transcription factor GATA-2

1

20

High-throughput

0.479

High

641379

PAX6
Paired box protein Pax-6

1

20

High-throughput

0.479

High

679098

TLX1
T-cell leukemia homeobox protein 1

1

20

High-throughput

0.479

High

878398

PAX9
Paired box protein Pax-9

1

20

High-throughput

0.479

High

882123

GSC
Homeobox protein goosecoid

1

20

High-throughput

0.479

High

980927

PAX8
Paired box protein Pax-8

1

20

High-throughput

0.479

High

980930

FOXI1
Forkhead box protein I1

1

20

High-throughput

0.479

High

980931

FOXL1
Forkhead box protein L1

1

20

High-throughput

0.479

High

980932

HDAC1
Histone deacetylase 1

1

20

Small-scale

0.479

High

980935

TBR1
T-box brain protein 1

1

20

High-throughput

0.479

High

980945

SP7
Transcription factor Sp7

1

16

High-throughput

0.479

High

980946

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

4

High-throughput

0.479

High

980949

FEV
Protein FEV

1

18

High-throughput

0.479

High

980956

VSX1
Visual system homeobox 1

1

20

High-throughput

0.479

High

980957

MKLN1
Muskelin

1

10

High-throughput

0.479

High

980959

KLF12
Krueppel-like factor 12

1

20

High-throughput

0.479

High

273424

PPM1B
Protein phosphatase 1B

1

0

Small-scale

0.458

High

496894

TAU
Microtubule-associated protein tau

1

16

High-throughput

0.445

High

980934

NADC
Nicotinate-nucleotide pyrophosphorylase [carboxylating]

1

3

High-throughput

0.437

High

980950

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.437

High

980954

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

4

High-throughput

0.437

High

980938

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

10

High-throughput

0.407

High


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Last updated: 15 Jul 2024