HitPredict

Interactor 1: Q8SYU5 (Q8SYU5)
RE33762p
Gene: DmelCG10086

Interactor 2: NEDD4 (Q9VVI3)
E3 ubiquitin-protein ligase Nedd-4 (DNedd4) (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase NEDD4)
Gene: NEDD4

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38270169
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 469 Dm			1 1007
+	Dm
		115611 Q8SYU5_DROME (1-469): 4.34e-151: 440: 100.00		M9PFK2_DROME (1-1007): 0: 952: 99.41
+	Dm
		1367624 Q9VI00_DROME (1-465): 1.43e-99: 307: 22.32		NEDD4_DROME (1-1007): 0: 962: 100.00
+	Dm
		115614 Q9VI00_DROME (1-465): 1.43e-99: 307: 22.32		M9PFK2_DROME (1-1007): 0: 952: 99.41
+	Hs
		1285052 ARRD3_HUMAN (3-409): 1.97e-106: 324: 19.86		NED4L_HUMAN (63-1007): 0: 904: 47.53
+	Hs
		808216 ARRD3_HUMAN (3-409): 1.97e-106: 324: 19.86		NEDD4_HUMAN (150-1007): 0: 770: 47.57
+	Hs
		1285047 ARRD3_HUMAN (3-409): 1.97e-106: 324: 19.86		ITCH_HUMAN (56-1004): 0: 757: 29.56
+	Hs
		1285070 ARRD3_HUMAN (3-409): 1.97e-106: 324: 19.86		WWP1_HUMAN (60-1004): 0: 750: 30.85
+	Dm
		1367634 Q9VI00_DROME (1-465): 1.43e-99: 307: 22.32		SUDX_DROME (70-1003): 0: 734: 29.72
+	Hs
		125633 ARRD3_HUMAN (3-409): 1.97e-106: 324: 19.86		WWP2_HUMAN (289-1004): 0: 685: 35.40
+	Hs
		125595 ARRD2_HUMAN (3-400): 1.47e-99: 306: 19.65		WWP2_HUMAN (289-1004): 0: 685: 35.40
+	Dm
		89895 Q8SYU5_DROME (1-469): 4.34e-151: 440: 100.00		D5SHR3_DROME (593-1004): 3.16e-176: 521: 46.28
+	Dm
		1249359 Q8SYU5_DROME (1-469): 4.34e-151: 440: 100.00		Q9W325_DROME (593-1004): 2.74e-174: 517: 46.28
+	Dm
		89897 Q9I7L0_DROME (1-450): 6.85e-112: 338: 31.68		D5SHR3_DROME (593-1004): 3.16e-176: 521: 46.28
+	Dm
		1337204 Q9I7L0_DROME (1-450): 6.85e-112: 338: 31.68		Q9W325_DROME (593-1004): 2.74e-174: 517: 46.28
+	Hs
		1192131 ARRD2_HUMAN (3-400): 1.47e-99: 306: 19.65		HUWE1_HUMAN (445-1005): 1.18e-162: 533: 33.06
+	Dm
		89904 Q9VI00_DROME (1-465): 1.43e-99: 307: 22.32		D5SHR3_DROME (593-1004): 3.16e-176: 521: 46.28
+	Dm
		1367630 Q9VI00_DROME (1-465): 1.43e-99: 307: 22.32		Q9W325_DROME (593-1004): 2.74e-174: 517: 46.28
+	Dm
		1249317 Q8SYU5_DROME (1-469): 4.34e-151: 440: 100.00		SMUF1_DROME (69-621): 1.71e-32: 138: 15.37
+	Ce
		1341514 Q9XXI4_CAEEL (5-442): 1.81e-108: 329: 22.00		WWP1_CAEEL (66-461): 4.68e-17: 88.4: 16.51
+	Hs
		1285085 ARRD3_HUMAN (3-409): 1.97e-106: 324: 19.86		HECW2_HUMAN (202-636): 2.04e-11: 70.3: 12.18