Protein: SMG5
Nonsense-mediated mRNA decay factor SMG5 (EST1-like protein B) (LPTS-RP1) (LPTS-interacting protein) (SMG-5 homolog) (hSMG-5)

Gene: SMG5
Organism: Homo sapiens
Interactions: 76
UniProt ID: Q9UPR3

Gene Ontology (top 5):
GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0005634 - nucleus
GO:0005697 - telomerase holoenzyme complex
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1266721

SMG7
Nonsense-mediated mRNA decay factor SMG7

2

4

Small-scale

0.767

High

1200073

EST1A
Telomerase-binding protein EST1A

2

4

Small-scale

0.754

High

387749

P53
Cellular tumor antigen p53

3

1

Small-scale

0.662

High

1272407

RENT1
Regulator of nonsense transcripts 1

3

6

Small-scale

0.657

High

323315

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

1

High-throughput

0.584

High

1132272

CF141
Uncharacterized protein C6orf141

2

1

High-throughput

0.574

High

154067

TERT
Telomerase reverse transcriptase

1

1

Small-scale

0.561

High

1357473

CHIP
E3 ubiquitin-protein ligase CHIP

1

2

Small-scale

0.561

High

1316234

DUS16
Dual specificity protein phosphatase 16

1

1

High-throughput

0.536

High

1051210

BTG3
Protein BTG3

1

0

High-throughput

0.518

High

886218

H2B1D
Histone H2B type 1-D

1

2

High-throughput

0.515

High

1087487

H2B2E
Histone H2B type 2-E

1

2

High-throughput

0.515

High

1307154

H2B1L
Histone H2B type 1-L

1

2

High-throughput

0.515

High

1101795

CF184
Cilia- and flagella-associated protein 184

1

1

High-throughput

0.489

High

1238371

SYT2
Synaptotagmin-2

1

1

High-throughput

0.489

High

396060

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

47896

RBM47
RNA-binding protein 47

1

4

High-throughput

0.479

High

166341

GRRE1
Granule associated Rac and RHOG effector protein 1

1

1

High-throughput

0.479

High

257725

ANR17
Ankyrin repeat domain-containing protein 17

1

3

High-throughput

0.479

High

302623

CE152
Centrosomal protein of 152 kDa

1

1

High-throughput

0.479

High

644353

TTP
mRNA decay activator protein ZFP36

1

3

High-throughput

0.479

High

668446

RBMS1
RNA-binding motif, single-stranded-interacting protein 1

1

3

High-throughput

0.479

High

719235

PHB1
Prohibitin 1

1

1

Small-scale

0.479

High

821091

PRC2A
Protein PRRC2A

1

8

High-throughput

0.479

High

843965

FXR1
RNA-binding protein FXR1

1

6

High-throughput

0.479

High

966671

OTUD4
OTU domain-containing protein 4

1

2

High-throughput

0.479

High

1021474

ANK3
Ankyrin-3

1

2

High-throughput

0.479

High

1049924

UBP2L
Ubiquitin-associated protein 2-like

1

3

High-throughput

0.479

High

1056780

PUM1
Pumilio homolog 1

1

1

High-throughput

0.479

High

1068981

PCM1
Pericentriolar material 1 protein

1

1

High-throughput

0.479

High

1089588

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

5

High-throughput

0.479

High

1129617

SMAG2
Protein Smaug homolog 2

1

1

High-throughput

0.479

High

1159116

CEP85
Centrosomal protein of 85 kDa

1

1

High-throughput

0.479

High

1168870

MEX3B
RNA-binding protein MEX3B

1

1

High-throughput

0.479

High

1172286

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1192411

YTHD3
YTH domain-containing family protein 3

1

6

High-throughput

0.479

High

1198417

PATL1
Protein PAT1 homolog 1

1

4

High-throughput

0.479

High

1219269

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

1

High-throughput

0.479

High

1224442

XRN1
5'-3' exoribonuclease 1

1

3

High-throughput

0.479

High

1242164

LS14A
Protein LSM14 homolog A

1

1

High-throughput

0.479

High

1242698

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

6

High-throughput

0.479

High

1259812

SMAP2
Stromal membrane-associated protein 2

1

1

High-throughput

0.479

High

1267905

CNOT9
CCR4-NOT transcription complex subunit 9

1

1

High-throughput

0.479

High

1272134

CELF1
CUGBP Elav-like family member 1

1

3

High-throughput

0.479

High

1272500

DAZL
Deleted in azoospermia-like

1

5

High-throughput

0.479

High

1294280

FUBP3
Far upstream element-binding protein 3

1

3

High-throughput

0.479

High

1297143

CNO6L
CCR4-NOT transcription complex subunit 6-like

1

1

High-throughput

0.479

High

1310220

LZTS2
Leucine zipper putative tumor suppressor 2

1

2

High-throughput

0.479

High

1316067

HDAC8
Histone deacetylase 8

1

2

Small-scale

0.479

High

1317758

CPEB1
Cytoplasmic polyadenylation element-binding protein 1

1

3

High-throughput

0.479

High

1318818

UNK
RING finger protein unkempt homolog

1

4

High-throughput

0.479

High

1327014

MKRN2
E3 ubiquitin-protein ligase makorin-2

1

2

High-throughput

0.479

High

1330884

Q9H4D1
Protein kinase

1

6

High-throughput

0.479

High

1331642

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

1332781

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

1333017

TDRD3
Tudor domain-containing protein 3

1

2

High-throughput

0.479

High

1336011

MOV10
Helicase MOV-10

1

6

High-throughput

0.479

High

1342892

DCP1A
mRNA-decapping enzyme 1A

1

1

High-throughput

0.479

High

1344416

4ET
Eukaryotic translation initiation factor 4E transporter

1

2

High-throughput

0.479

High

1347627

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

2

High-throughput

0.479

High

1349349

CNOT2
CCR4-NOT transcription complex subunit 2

1

3

High-throughput

0.479

High

1355899

CNOT7
CCR4-NOT transcription complex subunit 7

1

1

High-throughput

0.479

High

1357717

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

4

High-throughput

0.479

High

1357733

FBW1A
F-box/WD repeat-containing protein 1A

1

2

High-throughput

0.479

High

1357734

R3HD2
R3H domain-containing protein 2

1

5

High-throughput

0.479

High

1357736

YTHD2
YTH domain-containing family protein 2

1

6

High-throughput

0.479

High

1357737

RBM8A
RNA-binding protein 8A

1

4

Small-scale

0.479

High

1357738

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

3

High-throughput

0.479

High

308043

ZWINT
ZW10 interactor

1

0

Small-scale

0.458

High

1355409

UBQL2
Ubiquilin-2

1

0

High-throughput

0.458

High

1318143

REN3B
Regulator of nonsense transcripts 3B

1

2

Small-scale

0.445

High

1328752

REN3A
Regulator of nonsense transcripts 3A

1

2

Small-scale

0.445

High

1344838

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

1139895

OBI1
ORC ubiquitin ligase 1

1

1

High-throughput

0.437

High

1242064

RN214
RING finger protein 214

1

1

High-throughput

0.437

High

1357735

RT18C
Small ribosomal subunit protein bS18m

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024