Interactor 1: ALKL1 (Q6UXT8)
ALK and LTK ligand 1 (Augmentor beta) (AUG-beta)
Gene: ALKAL1
Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.57 | 1.00 | 0.761 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26418745 |
| Identification Methods | surface plasmon resonance, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, enzyme linked immunosorbent assay |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ALKL1_2~Gly_rich |
| Common GO terms | GO:0005886 - plasma membrane GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway GO:0030298 - receptor signaling protein tyrosine kinase activator activity |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
