HitPredict

Interactor 1: WWP2 (O00308)
NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (Atrophin-1-interacting protein 2) (AIP2) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2)
Gene: WWP2

Interactor 2: CPSF5 (O43809)
Cleavage and polyadenylation specificity factor subunit 5 (Cleavage and polyadenylation specificity factor 25 kDa subunit) (CPSF 25 kDa subunit) (Cleavage factor Im complex 25 kDa subunit) (CFIm25) (Nucleoside diphosphate-linked moiety X motif 21) (Nudix motif 21) (Nudix hydrolase 21) (Pre-mRNA cleavage factor Im 68 kDa subunit)
Gene: NUDT21

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25071155, 31048545
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 870 Hs			1 227
+	Hs
		215016 ITCH_HUMAN (1-870): 0: 902: 54.26		CPSF5_HUMAN (1-227): 4.65e-152: 423: 100.00
+	Hs
		214877 NEDD4_HUMAN (90-867): 0: 731: 35.94		CPSF5_HUMAN (1-227): 4.65e-152: 423: 100.00
+	Hs
		214975 HUWE1_HUMAN (241-869): 7.77e-179: 575: 30.03		CPSF5_HUMAN (1-227): 4.65e-152: 423: 100.00
+	Hs
		215043 SMUF1_HUMAN (1-385): 1.35e-45: 177: 17.77		CPSF5_HUMAN (1-227): 4.65e-152: 423: 100.00