HitPredict

Interactor 1: SMRC2 (Q8TAQ2)
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)
Gene: SMARCC2

Interactor 2: BRD9 (Q9H8M2)
Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS-40.8)
Gene: BRD9

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	28514442, 29374058, 24981860, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling GO:0006357 - regulation of transcription by RNA polymerase II GO:0016514 - SWI/SNF complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1214 Hs			1 597
+	Hs
		1272941 SMRC1_HUMAN (4-1082): 0: 957: 60.83		BRD9_HUMAN (1-597): 1.05e-144: 433: 100.00
+	Mm
		956812 SMRC1_MOUSE (4-1028): 0: 952: 64.13		BRD9_MOUSE (1-596): 1.99e-143: 429: 91.95
+	Hs
		1251634 SMRC2_HUMAN (1-1203): 0: 992: 100.00		BRD7_HUMAN (20-579): 2.88e-110: 346: 33.33
+	Mm
		292067 SMRC1_MOUSE (4-1028): 0: 952: 64.13		BRD7_MOUSE (1-579): 4.06e-113: 353: 34.42
+	Hs
		1272946 SMRC1_HUMAN (4-1082): 0: 957: 60.83		BRD7_HUMAN (20-579): 2.88e-110: 346: 33.33
+	Hs
		1199164 SMRC2_HUMAN (1-1203): 0: 992: 100.00		PB1_HUMAN (94-466): 8.39e-27: 118: 15.30
+	Hs
		1199176 SMRC1_HUMAN (4-1082): 0: 957: 60.83		PB1_HUMAN (94-466): 8.39e-27: 118: 15.30
+	Hs
		998902 SMRC2_HUMAN (1-1203): 0: 992: 100.00		EP300_HUMAN (238-403): 2.5e-10: 65.8: 12.09
+	Hs
		998950 SMRC1_HUMAN (4-1082): 0: 957: 60.83		EP300_HUMAN (238-403): 2.5e-10: 65.8: 12.09
+	Dm
		844327 Q9VF03_DROME (5-1126): 0: 723: 40.84		TAF1_DROME (2-535): 3.95e-55: 204: 13.77
+	Dm
		1362520 Q9VF03_DROME (5-1126): 0: 723: 40.84		Q9VC36_DROME (92-448): 1.2e-22: 105: 14.96
+	Sc
		715346 RSC8_YEAST (336-751): 4.61e-104: 342: 28.30		SPT7_YEAST (9-533): 6.65e-50: 188: 14.00
+	Sc
		728711 RSC8_YEAST (336-751): 4.61e-104: 342: 28.30		BDF1_YEAST (83-508): 6.49e-47: 177: 12.92
+	Sc
		696128 SWI3_YEAST (254-793): 1.23e-96: 329: 26.48		SPT7_YEAST (9-533): 6.65e-50: 188: 14.00
+	Sc
		797934 RSC8_YEAST (336-751): 4.61e-104: 342: 28.30		GCN5_YEAST (68-242): 3.04e-41: 156: 21.35
+	Sc
		696166 SWI3_YEAST (254-793): 1.23e-96: 329: 26.48		GCN5_YEAST (68-242): 3.04e-41: 156: 21.35
+	At
		1195144 SWI3B_ARATH (386-789): 1.61e-87: 293: 23.54		GTE11_ARATH (50-280): 6.94e-38: 150: 22.36
+	At
		1275616 SWI3C_ARATH (383-990): 2.21e-79: 280: 20.82		GTE11_ARATH (50-280): 6.94e-38: 150: 22.36
+	At
		1258938 SWI3A_ARATH (422-725): 1.3e-64: 230: 22.83		GTE11_ARATH (50-280): 6.94e-38: 150: 22.36
+	Hs
		1138818 MYSM1_HUMAN (276-523): 7.61e-53: 202: 22.96		KAT2B_HUMAN (114-229): 3.28e-23: 106: 27.27