Protein: AATM
Aspartate aminotransferase, mitochondrial (mAspAT) (EC 2.6.1.1) (EC 2.6.1.7) (Fatty acid-binding protein) (FABP-1) (Glutamate oxaloacetate transaminase 2) (Kynurenine aminotransferase 4) (Kynurenine aminotransferase IV) (Kynurenine--oxoglutarate transaminase 4) (Kynurenine--oxoglutarate transaminase IV) (Plasma membrane-associated fatty acid-binding protein) (FABPpm) (Transaminase A)

Gene: AATM, GOT2
Organism: Homo sapiens
Interactions: 110
UniProt ID: P00505

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0004069 - L-aspartate:2-oxoglutarate aminotransferase activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

361983

AATM
Aspartate aminotransferase, mitochondrial

1

5

High-throughput

0.618

High

361994

HSP7C
Heat shock cognate 71 kDa protein

2

1

Small-scale

0.595

High

240427

PRKN
E3 ubiquitin-protein ligase parkin

2

3

High-throughput

0.584

High

362020

TERA
Transitional endoplasmic reticulum ATPase

2

1

High-throughput

0.571

High

362012

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

2

High-throughput

0.536

High

362063

KPCD2
Serine/threonine-protein kinase D2

1

1

High-throughput

0.536

High

362003

CDK2
Cyclin-dependent kinase 2

2

1

High-throughput

0.533

High

362049

THOC7
THO complex subunit 7

1

0

High-throughput

0.518

High

213756

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

High-throughput

0.513

High

362030

KPCZ
Protein kinase C zeta type

1

0

High-throughput

0.513

High

362041

MYLK
Myosin light chain kinase, smooth muscle

1

0

High-throughput

0.513

High

361988

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

1

High-throughput

0.508

High

362007

3MG
DNA-3-methyladenine glycosylase

1

0

High-throughput

0.493

High

361987

SAMP
Serum amyloid P-component

1

0

High-throughput

0.486

High

362011

GLRX1
Glutaredoxin-1

1

0

High-throughput

0.486

High

123307

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

1

High-throughput

0.479

High

137905

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

2

Small-scale

0.479

High

254499

EIF1B
Eukaryotic translation initiation factor 1b

1

1

High-throughput

0.479

High

361986

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

2

High-throughput

0.479

High

361989

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.479

High

361992

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

2

High-throughput

0.479

High

361995

EPB41
Protein 4.1

1

1

High-throughput

0.479

High

362001

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

1

High-throughput

0.479

High

362004

U2AF2
Splicing factor U2AF 65 kDa subunit

1

4

High-throughput

0.479

High

362006

CALR
Calreticulin

1

1

High-throughput

0.479

High

362010

FUS
RNA-binding protein FUS

1

1

High-throughput

0.479

High

362013

MDHM
Malate dehydrogenase, mitochondrial

1

3

High-throughput

0.479

High

362016

UTRN
Utrophin

1

3

High-throughput

0.479

High

362018

GDIB
Rab GDP dissociation inhibitor beta

1

1

High-throughput

0.479

High

362019

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

1

Small-scale

0.479

High

362025

ARF6
ADP-ribosylation factor 6

1

1

High-throughput

0.479

High

362026

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

3

Small-scale

0.479

High

362028

EWS
RNA-binding protein EWS

1

1

High-throughput

0.479

High

362031

TADBP
TAR DNA-binding protein 43

1

1

Small-scale

0.479

High

362036

RBM39
RNA-binding protein 39

1

1

High-throughput

0.479

High

362042

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.479

High

362045

PPCEL
Prolyl endopeptidase-like

1

2

High-throughput

0.479

High

362062

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

1

Small-scale

0.479

High

362076

TNIK
TRAF2 and NCK-interacting protein kinase

1

1

High-throughput

0.479

High

361991

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

361999

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

0

High-throughput

0.458

High

362002

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.458

High

362008

5HT7R
5-hydroxytryptamine receptor 7

1

0

High-throughput

0.458

High

362015

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

0

High-throughput

0.458

High

362033

PAK2
Serine/threonine-protein kinase PAK 2

1

0

High-throughput

0.458

High

362050

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

0

High-throughput

0.458

High

362053

SV2A
Synaptic vesicle glycoprotein 2A

1

0

High-throughput

0.458

High

362054

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

362056

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

362071

PD1L1
Programmed cell death 1 ligand 1

1

0

High-throughput

0.458

High

362074

ABCF2
ATP-binding cassette sub-family F member 2

1

0

High-throughput

0.458

High

362077

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

1

0

High-throughput

0.458

High

361990

JUN
Transcription factor Jun

1

1

High-throughput

0.445

High

361993

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.445

High

361998

GDC
Solute carrier family 25 member 16

1

1

High-throughput

0.445

High

362021

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.445

High

362035

DAG1
Dystroglycan 1

1

1

Small-scale

0.445

High

362047

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.445

High

362065

S2532
Solute carrier family 25 member 32

1

1

High-throughput

0.445

High

105054

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

294807

BCAR3
Breast cancer anti-estrogen resistance protein 3

1

1

High-throughput

0.437

High

361997

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

362005

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

362009

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

362014

BCL6
B-cell lymphoma 6 protein

1

1

High-throughput

0.437

High

362017

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

1

High-throughput

0.437

High

362032

RFA4
Replication protein A 30 kDa subunit

1

2

High-throughput

0.437

High

362039

BRD3
Bromodomain-containing protein 3

1

2

High-throughput

0.437

High

362046

BRDT
Bromodomain testis-specific protein

1

1

High-throughput

0.437

High

362051

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

362059

CSN5
COP9 signalosome complex subunit 5

1

2

High-throughput

0.437

High

362066

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.437

High

362070

ANM7
Protein arginine N-methyltransferase 7

1

2

High-throughput

0.437

High

362072

HDAC6
Protein deacetylase HDAC6

1

1

High-throughput

0.437

High

362079

HDAC5
Histone deacetylase 5

1

1

High-throughput

0.437

High

126949

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.426

High

361996

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

362000

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

362022

NAC3
Sodium/calcium exchanger 3

1

0

High-throughput

0.426

High

362023

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

0

High-throughput

0.426

High

362055

S41A1
Solute carrier family 41 member 1

1

0

High-throughput

0.426

High

362048

CP135
Centrosomal protein of 135 kDa

1

1

High-throughput

0.407

High

362078

SHOC2
Leucine-rich repeat protein SHOC-2

2

0

High-throughput

0.298

High

362040

ZMY11
Zinc finger MYND domain-containing protein 11

1

0

High-throughput

0.279

Low

362058

PHOP1
Phosphoethanolamine/phosphocholine phosphatase

1

0

High-throughput

0.279

Low

362068

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

0

High-throughput

0.279

Low

362069

CNBP1
Beta-catenin-interacting protein 1

1

0

High-throughput

0.269

Low

141736

CCL21
C-C motif chemokine 21

1

0

High-throughput

0.265

Low

352816

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

361984

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

361985

SOMA
Somatotropin

1

0

High-throughput

0.249

Low

362024

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

362027

CCNA1
Cyclin-A1

1

0

High-throughput

0.249

Low

362034

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.249

Low

362037

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.249

Low

362038

CUL7
Cullin-7

1

0

High-throughput

0.249

Low

362043

E2F4
Transcription factor E2F4

1

0

High-throughput

0.249

Low

362044

TTLL9
Probable tubulin polyglutamylase TTLL9

1

0

High-throughput

0.249

Low

362052

UBP53
Ubiquitin carboxyl-terminal hydrolase 53

1

0

Small-scale

0.249

Low

362057

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.249

Low

362061

DYH11
Dynein axonemal heavy chain 11

1

0

High-throughput

0.249

Low

362064

ATG5
Autophagy protein 5

1

0

High-throughput

0.249

Low

362073

TRM7
tRNA

1

0

High-throughput

0.249

Low

362075

SEPT9
Septin-9

1

0

Small-scale

0.249

Low

362080

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.249

Low

362081

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.249

Low

362067

ZDHC6
Palmitoyltransferase ZDHHC6

1

0

High-throughput

0.238

Low

362029

P
P protein

1

0

High-throughput

0.232

Low

362060

WNT2B
Protein Wnt-2b

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025