HitPredict

Interactor 1: RIN3 (Q8TB24)
Ras and Rab interactor 3 (Ras interaction/interference protein 3)
Gene: RIN3

Interactor 2: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.576

Property	Details
Experiments	25814554, unassigned1126
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 985 Hs			1 1164
+	Hs
		1044795 RIN1_HUMAN (6-327): 3.07e-21: 101: 26.32		TSC1_HUMAN (1-1164): 0: 725: 100.00
+	Hs
		551784 RIN3_HUMAN (1-985): 1.3e-180: 552: 100.00		DESP_HUMAN (570-1151): 1.05e-21: 104: 11.54
+	Hs
		1044786 RIN1_HUMAN (6-327): 3.07e-21: 101: 26.32		Q86WV8_HUMAN (1-343): 3.4e-177: 526: 100.00
+	Hs
		166047 SYNJ2_HUMAN (181-524): 2.35e-51: 199: 19.77		DCTN1_HUMAN (540-1022): 9.26e-59: 223: 16.33
+	Hs
		1051503 RABX5_HUMAN (548-876): 7.79e-51: 189: 15.32		DCTN1_HUMAN (540-1022): 9.26e-59: 223: 16.33
+	Hs
		1051517 MACF1_HUMAN (588-905): 2.12e-44: 178: 15.92		DCTN1_HUMAN (540-1022): 9.26e-59: 223: 16.33
+	Hs
		725073 MACF1_HUMAN (588-905): 2.12e-44: 178: 15.92		MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40
+	Hs
		149428 MACF1_HUMAN (588-905): 2.12e-44: 178: 15.92		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		110636 H3BPE1_HUMAN (588-865): 3.07e-40: 164: 14.68		MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40
+	Hs
		149481 PCLO_HUMAN (183-758): 1.17e-11: 71.6: 12.04		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		148573 SC24C_HUMAN (104-426): 8.78e-10: 64.8: 11.28		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78