HitPredict

Interactor 1: LNX1 (Q8TBB1)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Interactor 2: BACD1 (Q8WZ19)
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 (hBACURD1) (BTB/POZ domain-containing protein KCTD13) (Polymerase delta-interacting protein 1) (TNFAIP1-like protein)
Gene: KCTD13

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.692

Property	Details
Experiments	16189514, 32296183, 29892012, unassigned1304
Identification Methods	two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0016567 - protein ubiquitination
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 728 Hs			1 329
+	Hs
		1045929 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		BACD2_HUMAN (23-329): 7.29e-132: 379: 64.50
+	Hs
		1174576 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		KCTD1_HUMAN (16-265): 1.65e-56: 185: 20.15
+	Hs
		1252409 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		KCTD7_HUMAN (3-176): 2.07e-41: 147: 31.64
+	Hs
		1235348 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		KCD17_HUMAN (41-192): 1.02e-40: 146: 28.93
+	Hs
		1241184 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		KCTD6_HUMAN (40-215): 1.51e-41: 146: 28.25
+	Hs
		1183868 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		KCTD9_HUMAN (14-166): 7.06e-35: 132: 33.33
+	Hs
		942389 DLG4_HUMAN (581-725): 3.01e-21: 100: 22.22		KCND2_HUMAN (1-237): 1.91e-65: 218: 18.93
+	Hs
		1020242 PTN13_HUMAN (455-725): 4.02e-23: 107: 15.44		KCTD3_HUMAN (24-170): 9.36e-41: 153: 24.32
+	Hs
		1050021 SCRIB_HUMAN (265-624): 2.64e-15: 82.4: 13.52		KCNB2_HUMAN (9-204): 1.69e-41: 155: 22.97
+	Hs
		1057230 DLG3_HUMAN (619-713): 1.3e-14: 79.7: 28.87		KCTD2_HUMAN (6-192): 1.44e-43: 152: 24.49
+	Hs
		1132930 NHRF3_HUMAN (133-355): 1.14e-11: 69.7: 12.56		KCTD3_HUMAN (24-170): 9.36e-41: 153: 24.32
+	Hs
		1057225 NHRF3_HUMAN (133-355): 1.14e-11: 69.7: 12.56		KCTD2_HUMAN (6-192): 1.44e-43: 152: 24.49
+	Hs
		1132926 NHRF3_HUMAN (133-355): 1.14e-11: 69.7: 12.56		KCTD5_HUMAN (34-192): 1.17e-42: 149: 24.55
+	Hs
		1132909 NHRF3_HUMAN (133-355): 1.14e-11: 69.7: 12.56		KCD17_HUMAN (41-192): 1.02e-40: 146: 28.93
+	Hs
		1050010 SCRIB_HUMAN (265-624): 2.64e-15: 82.4: 13.52		SHKB1_HUMAN (23-143): 9.04e-28: 115: 31.97
+	Hs
		1132910 NHRF3_HUMAN (133-355): 1.14e-11: 69.7: 12.56		SHKB1_HUMAN (23-143): 9.04e-28: 115: 31.97