HitPredict

Interactor 1: LNX1 (Q8TBB1)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Interactor 2: TRI39 (Q9HCM9)
E3 ubiquitin-protein ligase TRIM39 (EC 2.3.2.27) (RING finger protein 23) (RING-type E3 ubiquitin transferase TRIM39) (Testis-abundant finger protein) (Tripartite motif-containing protein 39)
Gene: TRIM39

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.871

Property	Details
Experiments	25416956, 32296183, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	zf-B_box~zf-C3HC4
Common GO terms	GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 728 Hs			1 518
+	Hs
		585019 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		RO52_HUMAN (15-513): 3.5e-141: 417: 38.92
+	Hs
		536942 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		TRI27_HUMAN (15-518): 7.9e-137: 407: 37.28
+	Hs
		1115440 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		TRI60_HUMAN (17-518): 1.31e-130: 389: 38.42
+	Hs
		1149890 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		TRI68_HUMAN (16-518): 7.07e-130: 388: 35.45
+	Hs
		1204896 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		TRI50_HUMAN (18-510): 4.67e-112: 342: 26.85
+	Hs
		1252534 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		TRI10_HUMAN (15-502): 1.3e-109: 336: 34.55
+	Hs
		1020183 PTN13_HUMAN (455-725): 4.02e-23: 107: 15.44		TRI72_HUMAN (17-518): 8.71e-100: 311: 24.76