Protein: AKT3
RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase B gamma) (PKB gamma) (RAC-PK-gamma) (STK-2)

Gene: AKT3
Organism: Homo sapiens
Interactions: 74
UniProt ID: Q9Y243

Gene Ontology (top 5):
GO:0000002 - mitochondrial genome maintenance
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1083052

CDC37
Hsp90 co-chaperone Cdc37

4

14

Small-scale

0.895

High

432376

HS90A
Heat shock protein HSP 90-alpha

3

20

High-throughput

0.861

High

438633

HS90B
Heat shock protein HSP 90-beta

2

20

High-throughput

0.811

High

682081

AKT1
RAC-alpha serine/threonine-protein kinase

2

17

High-throughput

0.811

High

1035058

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

2

11

High-throughput

0.811

High

836099

GSK3B
Glycogen synthase kinase-3 beta

2

20

Small-scale

0.778

High

983943

KPCZ
Protein kinase C zeta type

1

20

Small-scale

0.756

High

1377010

SNX8
Sorting nexin-8

2

4

High-throughput

0.726

High

1123447

H90B4
Putative heat shock protein HSP 90-beta 4

2

20

High-throughput

0.712

High

1123464

H90B3
Putative heat shock protein HSP 90-beta-3

2

20

High-throughput

0.712

High

1123514

HS905
Putative heat shock protein HSP 90-alpha A5

2

20

High-throughput

0.712

High

1123562

HS904
Putative heat shock protein HSP 90-alpha A4

2

20

High-throughput

0.712

High

624380

MYL9
Myosin regulatory light polypeptide 9

1

3

High-throughput

0.691

High

682218

AKT2
RAC-beta serine/threonine-protein kinase

1

17

High-throughput

0.691

High

863606

COPA
Coatomer subunit alpha

1

5

High-throughput

0.691

High

1078069

HERC1
Probable E3 ubiquitin-protein ligase HERC1

1

20

High-throughput

0.691

High

1120907

PKHO1
Pleckstrin homology domain-containing family O member 1

1

2

Small-scale

0.665

High

1305461

CHP1
Calcineurin B homologous protein 1

1

0

High-throughput

0.656

High

931045

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

2

11

Small-scale

0.629

High

1297038

ANM6
Protein arginine N-methyltransferase 6

2

2

High-throughput

0.628

High

1298808

TOX2
TOX high mobility group box family member 2

2

6

High-throughput

0.628

High

50631

PKHG3
Pleckstrin homology domain-containing family G member 3

1

8

High-throughput

0.618

High

254137

WDR1
WD repeat-containing protein 1

1

7

High-throughput

0.618

High

1234155

AFAP1
Actin filament-associated protein 1

1

3

High-throughput

0.618

High

233019

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

18

Small-scale

0.618

High

538446

ENPL
Endoplasmin

1

20

High-throughput

0.618

High

590239

CCNA2
Cyclin-A2

1

3

Small-scale

0.618

High

1162538

Q6PK50
Heat shock protein HSP 90-beta

1

20

High-throughput

0.618

High

1172970

PHLP2
PH domain leucine-rich repeat-containing protein phosphatase 2

1

15

Small-scale

0.618

High

1356444

DP13A
DCC-interacting protein 13-alpha

1

6

Small-scale

0.618

High

1223306

PIANP
PILR alpha-associated neural protein

2

0

High-throughput

0.602

High

1302424

IWS1
Protein IWS1 homolog

1

2

Small-scale

0.561

High

788236

CASP3
Caspase-3

1

4

Small-scale

0.536

High

808324

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

19

High-throughput

0.536

High

214695

MYO1B
Unconventional myosin-Ib

1

7

High-throughput

0.536

High

358571

CO1A1
Collagen alpha-1(I) chain

1

2

High-throughput

0.536

High

397000

HMGN1
Non-histone chromosomal protein HMG-14

1

2

High-throughput

0.536

High

414117

GELS
Gelsolin

1

1

High-throughput

0.536

High

598381

FLNA
Filamin-A

1

2

High-throughput

0.536

High

670287

MARCS
Myristoylated alanine-rich C-kinase substrate

1

3

High-throughput

0.536

High

804000

NSF
Vesicle-fusing ATPase

1

6

High-throughput

0.536

High

813853

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.536

High

851000

HDGF
Hepatoma-derived growth factor

1

3

High-throughput

0.536

High

926058

AP2B1
AP-2 complex subunit beta

1

5

High-throughput

0.536

High

946334

BASP1
Brain acid soluble protein 1

1

2

High-throughput

0.536

High

957223

DAB2
Disabled homolog 2

1

9

High-throughput

0.536

High

1032824

PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B

1

5

High-throughput

0.536

High

1052513

FLOT2
Flotillin-2

1

2

High-throughput

0.536

High

1166751

ABH15
Protein ABHD15

1

1

High-throughput

0.536

High

1186099

MICA3
[F-actin]-monooxygenase MICAL3

1

3

High-throughput

0.536

High

865097

TTC3
E3 ubiquitin-protein ligase TTC3

1

8

Small-scale

0.534

High

880333

TCL1A
T-cell leukemia/lymphoma protein 1A

1

7

Small-scale

0.515

High

254839

COBL
Protein cordon-bleu

1

0

High-throughput

0.513

High

596493

PTMS
Parathymosin

1

0

High-throughput

0.513

High

900320

RL37A
Large ribosomal subunit protein eL43

1

0

High-throughput

0.513

High

1377011

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.513

High

358932

CRYAA
Alpha-crystallin A chain

1

10

High-throughput

0.501

High

1299664

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

19

High-throughput

0.501

High

1377009

FBX7
F-box only protein 7

1

4

High-throughput

0.501

High

555218

CD44
CD44 antigen

1

2

High-throughput

0.489

High

707403

S10A3
Protein S100-A3

1

11

High-throughput

0.489

High

984683

CALD1
Caldesmon

1

16

High-throughput

0.489

High

1055200

K1H2
Keratin, type I cuticular Ha2

1

8

High-throughput

0.489

High

1298544

DOCK7
Dedicator of cytokinesis protein 7

1

2

High-throughput

0.489

High

932075

TPM4
Tropomyosin alpha-4 chain

1

7

High-throughput

0.479

High

966790

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

2

Small-scale

0.479

High

1041287

CUL1
Cullin-1

1

4

Small-scale

0.479

High

451333

TPM1
Tropomyosin alpha-1 chain

1

7

High-throughput

0.437

High

1138643

OTUD1
OTU domain-containing protein 1

1

4

Small-scale

0.437

High

99847

F5H7S3
Tropomyosin alpha-1 chain

1

7

High-throughput

0.407

High

111618

K7ENT6
Tropomyosin 4

1

7

High-throughput

0.407

High

1241405

SEN2
tRNA-splicing endonuclease subunit Sen2

1

0

High-throughput

0.279

Low

1287630

KCD12
BTB/POZ domain-containing protein KCTD12

1

0

Small-scale

0.249

Low

1301420

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024