HitPredict

Interactor 1: Q8TBR3 (Q8TBR3)
Fusion (Involved in t(1216) in malignant liposarcoma)
Gene: FUS

Interactor 2: DUX4 (Q9UBX2)
Double homeobox protein 4 (Double homeobox protein 10)
Gene: DUX4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26816005
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 526 Hs			1 424
+	Hs
		727079 FUS_HUMAN (1-526): 1.99e-39: 152: 99.81		DUX4_HUMAN (1-424): 1.09e-57: 196: 100.00
+	Hs
		1164163 Q8TBR3_HUMAN (1-526): 3.42e-39: 151: 100.00		DUX4C_HUMAN (1-374): 2.41e-42: 154: 94.12
+	Hs
		1031485 PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00		DUX4_HUMAN (1-424): 1.09e-57: 196: 100.00
+	Hs
		1153489 Q6IQ30_HUMAN (280-379): 1.33e-12: 72.4: 22.00		DUX4_HUMAN (1-424): 1.09e-57: 196: 100.00
+	Hs
		516726 PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44		DUX4_HUMAN (1-424): 1.09e-57: 196: 100.00
+	Hs
		72219 B3KT93_HUMAN (184-382): 2.61e-12: 71.2: 12.44		DUX4_HUMAN (1-424): 1.09e-57: 196: 100.00
+	Hs
		91465 E7ERJ7_HUMAN (281-391): 3.63e-11: 67.8: 20.72		DUX4_HUMAN (1-424): 1.09e-57: 196: 100.00
+	Mm
		1142779 EWS_MOUSE (3-451): 2.8e-30: 127: 35.37		Q8VD35_MOUSE (13-95): 4.78e-11: 65: 31.33
+	Hs
		516407 PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44		LHX1_HUMAN (59-302): 1.61e-25: 109: 18.90
+	Mm
		665766 PABP1_MOUSE (184-382): 3.6e-12: 70.8: 12.44		Q8VD35_MOUSE (13-95): 4.78e-11: 65: 31.33