HitPredict

Interactor 1: PNPT1 (Q8TCS8)
Polyribonucleotide nucleotidyltransferase 1, mitochondrial (EC 2.7.7.8) (3'-5' RNA exonuclease OLD35) (PNPase old-35) (Polynucleotide phosphorylase 1) (PNPase 1) (Polynucleotide phosphorylase-like protein)
Gene: PNPT1

Interactor 2: FAKD4 (Q969Z0)
FAST kinase domain-containing protein 4 (Cell cycle progression restoration protein 2) (Cell cycle progression protein 2) (Protein TBRG4) (Transforming growth factor beta regulator 4)
Gene: TBRG4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 32877691, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005739 - mitochondrion GO:0005759 - mitochondrial matrix GO:0051726 - regulation of cell cycle
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 783 Hs			1 631
+	Hs
		1253778 PNPT1_HUMAN (1-783): 0: 906: 100.00		FAKD2_HUMAN (30-630): 1.26e-160: 479: 18.79
+	Hs
		1062249 PNPT1_HUMAN (1-783): 0: 906: 100.00		FAKD3_HUMAN (40-623): 1.76e-143: 433: 21.39
+	Hs
		1185319 PNPT1_HUMAN (1-783): 0: 906: 100.00		FAKD5_HUMAN (25-543): 1.43e-129: 400: 18.05